Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/Txe-YefM
Location 4519799..4520301 Replicon chromosome
Accession NZ_CP092289
Organism Marinobacter sp. M1C

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag MIH19_RS21230 Protein ID WP_249006759.1
Coordinates 4519799..4520062 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MIH19_RS21235 Protein ID WP_249006760.1
Coordinates 4520059..4520301 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MIH19_RS21205 (MIH19_21205) 4515079..4516545 - 1467 WP_249006754.1 ABC transporter permease -
MIH19_RS21210 (MIH19_21210) 4516563..4517213 - 651 WP_249006755.1 ATP-binding cassette domain-containing protein -
MIH19_RS21215 (MIH19_21215) 4517213..4518061 - 849 WP_249006756.1 putative selenate ABC transporter substrate-binding protein -
MIH19_RS21220 (MIH19_21220) 4518341..4518979 - 639 WP_249006757.1 SGNH/GDSL hydrolase family protein -
MIH19_RS21225 (MIH19_21225) 4519370..4519699 - 330 WP_249006758.1 DHCW motif cupin fold protein -
MIH19_RS21230 (MIH19_21230) 4519799..4520062 - 264 WP_249006759.1 Txe/YoeB family addiction module toxin Toxin
MIH19_RS21235 (MIH19_21235) 4520059..4520301 - 243 WP_249006760.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MIH19_RS21240 (MIH19_21240) 4520541..4521488 - 948 WP_249006761.1 D-hexose-6-phosphate mutarotase -
MIH19_RS21245 (MIH19_21245) 4521899..4522153 - 255 WP_249006762.1 CopG family transcriptional regulator -
MIH19_RS21250 (MIH19_21250) 4522233..4522406 - 174 WP_249006763.1 BrnT family toxin -
MIH19_RS21255 (MIH19_21255) 4522536..4522952 - 417 WP_249006764.1 GFA family protein -
MIH19_RS21260 (MIH19_21260) 4523304..4523600 - 297 WP_249006765.1 type II toxin-antitoxin system RelE/ParE family toxin -
MIH19_RS21265 (MIH19_21265) 4523600..4523854 - 255 WP_249006766.1 type II toxin-antitoxin system ParD family antitoxin -
MIH19_RS21270 (MIH19_21270) 4524468..4524950 - 483 WP_249006768.1 SgcJ/EcaC family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4519370..4567768 48398


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-69)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10073.76 Da        Isoelectric Point: 10.2588

>T235908 WP_249006759.1 NZ_CP092289:c4520062-4519799 [Marinobacter sp. M1C]
VTWKLVYTKQAQKDAKKLAASSLKPKAQGLLALIAEDPYRRPPPFEKLIGDLAGAYSRRINIQHRVVYEVLEDERVVKVL
RLWSHYE

Download         Length: 264 bp

>T235908 NZ_LR134485:1997305-1997408 [Citrobacter youngae]
GGCAGGGTAACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9157.32 Da        Isoelectric Point: 4.1317

>AT235908 WP_249006760.1 NZ_CP092289:c4520301-4520059 [Marinobacter sp. M1C]
MTGITATEARSNLYRLIDETAESHQPIVIMGKRNRAVLVSEEDWSAIQETLYLLSVPGMRESIREGMETPMDQCDEELNW

Download         Length: 243 bp

>AT235908 NZ_LR134485:c1997413-1997203 [Citrobacter youngae]
CACATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTT
GGCATTAATGCAGGCTAAGTTACCCTGCCATTTAAGAATAGATGACAGCGCCAGGTTTTCCAGTCCGCGACTAAAGTGGT
CTGAAAAAAAGGGAGATTGTCACTCGCTACAATGTAAAAACCGCAAGTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References