Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1049742..1050295 Replicon chromosome
Accession NZ_CP092289
Organism Marinobacter sp. M1C

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MIH19_RS05065 Protein ID WP_249008947.1
Coordinates 1049742..1049996 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MIH19_RS05070 Protein ID WP_249007834.1
Coordinates 1050023..1050295 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MIH19_RS05015 (MIH19_05015) 1045059..1045331 - 273 WP_249007825.1 type II toxin-antitoxin system YafQ family toxin -
MIH19_RS05020 (MIH19_05020) 1045331..1045588 - 258 WP_249007826.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
MIH19_RS05025 (MIH19_05025) 1045940..1046434 - 495 WP_249007827.1 MgtC/SapB family protein -
MIH19_RS22405 1046494..1046616 + 123 WP_283164099.1 hypothetical protein -
MIH19_RS05030 (MIH19_05030) 1046785..1047300 + 516 WP_249007828.1 sn-glycerol-3-phosphate transporter -
MIH19_RS05035 (MIH19_05035) 1047610..1047696 - 87 WP_249008946.1 type II toxin-antitoxin system HicB family antitoxin -
MIH19_RS05040 (MIH19_05040) 1047798..1047929 - 132 WP_249007829.1 type II toxin-antitoxin system HicA family toxin -
MIH19_RS05045 (MIH19_05045) 1048209..1048559 + 351 WP_249007830.1 DUF2784 domain-containing protein -
MIH19_RS05050 (MIH19_05050) 1048746..1049003 + 258 WP_249007831.1 helix-turn-helix transcriptional regulator -
MIH19_RS05055 (MIH19_05055) 1049035..1049325 - 291 WP_249007832.1 type II toxin-antitoxin system RelE/ParE family toxin -
MIH19_RS05060 (MIH19_05060) 1049315..1049563 - 249 WP_249007833.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
MIH19_RS05065 (MIH19_05065) 1049742..1049996 - 255 WP_249008947.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MIH19_RS05070 (MIH19_05070) 1050023..1050295 - 273 WP_249007834.1 CopG family ribbon-helix-helix protein Antitoxin
MIH19_RS05075 (MIH19_05075) 1050456..1051040 - 585 WP_249007835.1 histidine phosphatase family protein -
MIH19_RS05080 (MIH19_05080) 1051073..1051279 - 207 WP_249007836.1 hypothetical protein -
MIH19_RS05085 (MIH19_05085) 1051428..1052171 - 744 WP_249007837.1 ParA family protein -
MIH19_RS05090 (MIH19_05090) 1052504..1053214 + 711 Protein_993 acyl-CoA dehydrogenase family protein -
MIH19_RS05095 (MIH19_05095) 1053441..1053626 + 186 WP_249007838.1 hypothetical protein -
MIH19_RS05100 (MIH19_05100) 1053668..1054468 - 801 WP_249007839.1 dienelactone hydrolase family protein -
MIH19_RS05105 (MIH19_05105) 1054628..1055200 + 573 WP_249007840.1 glutathione S-transferase N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1030151..1052171 22020


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9508.87 Da        Isoelectric Point: 7.3581

>T235901 WP_249008947.1 NZ_CP092289:c1049996-1049742 [Marinobacter sp. M1C]
MERCRKFLAAKAPEASRRAGQTIERHFLFLETATGIGRPFAEMPELRELVIAFGNSGYVALYHHEPADDAVYVLAFRHQK
EAGF

Download         Length: 255 bp

>T235901 NZ_LR134481:c1605495-1605112 [Haemophilus parainfluenzae]
ATGAAACAAGAATGGGAAGTAATTTTACAAGACCCACTTTTAAACTGGTTAAAAATGCTGGCAGAAGATGACGTATTAAA
AATCTATGCGGCGTTGGAATTACTATCAACAGAAGGTCCACAATTAAGCAGACCTTATGCGGATACGCTGCAAAGCTCTA
AATATACCAATTTAAAAGAATTGCGAGTACAGTCTAAATTATCGGTATTCCGTTTATTTTATATTTTCGATCCTGTCAGA
CAAGCGATTGTTTTGTGTGGCGGAGATAAGAAAGGCAAGAAAGAAAAGCTCTTTTACAAAGAGATGATTGCCCTAGCGGA
ACAAACCTATGATGATTACCTTTCTGAATTAACTAAGGAGCAAGAGAATGAGCGTAAAATTTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10545.71 Da        Isoelectric Point: 6.9791

>AT235901 WP_249007834.1 NZ_CP092289:c1050295-1050023 [Marinobacter sp. M1C]
MATSLKIDNTLKSRVHHIANQRRRSPHWIMLEAIQQYVEREEARESFKQEALASWSAYKETGRHLTGQEARAWLNTWGND
DEKAAPECHE

Download         Length: 273 bp

>AT235901 NZ_LR134481:c1605128-1604826 [Haemophilus parainfluenzae]
ATGAGCGTAAAATTTAAAGATCTGATGAATAATCTTCCAGCTGAAAAGCAAGCGAAAGTGAAAGCTATGGCAGACGATAT
GCGAATGGAGTTACAACTTTACCGTATTCGTGAAGAATTAGAGCTTTCACAAAAGCAAATGGCAGAAGCATTAAGTATTT
CTCAGCCGTCAGTTGTCGCCCTTGAAAAACGTGGCAATGACATTAAATTATCATCAGTTAAACGTTACATTGAAGCAATG
GGTGGTGTGTTAAATTTATCGGTTGAATTACCCACAGGAAAGACAGTTACTTTCAACTTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References