Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-YafN |
| Location | 1049035..1049563 | Replicon | chromosome |
| Accession | NZ_CP092289 | ||
| Organism | Marinobacter sp. M1C | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | MIH19_RS05055 | Protein ID | WP_249007832.1 |
| Coordinates | 1049035..1049325 (-) | Length | 97 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | MIH19_RS05060 | Protein ID | WP_249007833.1 |
| Coordinates | 1049315..1049563 (-) | Length | 83 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MIH19_RS05010 (MIH19_05010) | 1044322..1044795 | - | 474 | WP_249007824.1 | outer membrane protein assembly factor BamE | - |
| MIH19_RS05015 (MIH19_05015) | 1045059..1045331 | - | 273 | WP_249007825.1 | type II toxin-antitoxin system YafQ family toxin | - |
| MIH19_RS05020 (MIH19_05020) | 1045331..1045588 | - | 258 | WP_249007826.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | - |
| MIH19_RS05025 (MIH19_05025) | 1045940..1046434 | - | 495 | WP_249007827.1 | MgtC/SapB family protein | - |
| MIH19_RS22405 | 1046494..1046616 | + | 123 | WP_283164099.1 | hypothetical protein | - |
| MIH19_RS05030 (MIH19_05030) | 1046785..1047300 | + | 516 | WP_249007828.1 | sn-glycerol-3-phosphate transporter | - |
| MIH19_RS05035 (MIH19_05035) | 1047610..1047696 | - | 87 | WP_249008946.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| MIH19_RS05040 (MIH19_05040) | 1047798..1047929 | - | 132 | WP_249007829.1 | type II toxin-antitoxin system HicA family toxin | - |
| MIH19_RS05045 (MIH19_05045) | 1048209..1048559 | + | 351 | WP_249007830.1 | DUF2784 domain-containing protein | - |
| MIH19_RS05050 (MIH19_05050) | 1048746..1049003 | + | 258 | WP_249007831.1 | helix-turn-helix transcriptional regulator | - |
| MIH19_RS05055 (MIH19_05055) | 1049035..1049325 | - | 291 | WP_249007832.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| MIH19_RS05060 (MIH19_05060) | 1049315..1049563 | - | 249 | WP_249007833.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| MIH19_RS05065 (MIH19_05065) | 1049742..1049996 | - | 255 | WP_249008947.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| MIH19_RS05070 (MIH19_05070) | 1050023..1050295 | - | 273 | WP_249007834.1 | CopG family ribbon-helix-helix protein | - |
| MIH19_RS05075 (MIH19_05075) | 1050456..1051040 | - | 585 | WP_249007835.1 | histidine phosphatase family protein | - |
| MIH19_RS05080 (MIH19_05080) | 1051073..1051279 | - | 207 | WP_249007836.1 | hypothetical protein | - |
| MIH19_RS05085 (MIH19_05085) | 1051428..1052171 | - | 744 | WP_249007837.1 | ParA family protein | - |
| MIH19_RS05090 (MIH19_05090) | 1052504..1053214 | + | 711 | Protein_993 | acyl-CoA dehydrogenase family protein | - |
| MIH19_RS05095 (MIH19_05095) | 1053441..1053626 | + | 186 | WP_249007838.1 | hypothetical protein | - |
| MIH19_RS05100 (MIH19_05100) | 1053668..1054468 | - | 801 | WP_249007839.1 | dienelactone hydrolase family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1030151..1052171 | 22020 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 11097.04 Da Isoelectric Point: 10.7120
>T235900 WP_249007832.1 NZ_CP092289:c1049325-1049035 [Marinobacter sp. M1C]
MSSKYALEFKPSALKEWKKLAPALQAQFKKKLKQRLDDPHVPPDALSDLKNCYKIKLRSAGYRLVYEVENERIVVTVVAV
GKRERGAVYSRAHRRI
MSSKYALEFKPSALKEWKKLAPALQAQFKKKLKQRLDDPHVPPDALSDLKNCYKIKLRSAGYRLVYEVENERIVVTVVAV
GKRERGAVYSRAHRRI
Download Length: 291 bp
>T235900 NZ_LR134480:2382950-2383216 [Bordetella bronchiseptica]
ATGGATATCACCTACGACCCCGCCAAGAACGACAAGAACATTGCCGATCGCGGCCTGTCGTTCGAGTTGGTGTGTGGCTT
CGAGTGGGCCAGCGCGCTGGTGGTTGAGGATACCCGCCAGGTCTACGCCGAAACGCGCTATCAGGCGCTGGGCAAAATCG
ATGGCCGGCTCCATATGGTGGTATTCACGGTGCGCGGCGAGTCGCTGCGCATCATCAGCCTGCGTAAGGCAAATGCTCGT
GAGGTAGCTCGTTATGAAAAAGCCTGA
ATGGATATCACCTACGACCCCGCCAAGAACGACAAGAACATTGCCGATCGCGGCCTGTCGTTCGAGTTGGTGTGTGGCTT
CGAGTGGGCCAGCGCGCTGGTGGTTGAGGATACCCGCCAGGTCTACGCCGAAACGCGCTATCAGGCGCTGGGCAAAATCG
ATGGCCGGCTCCATATGGTGGTATTCACGGTGCGCGGCGAGTCGCTGCGCATCATCAGCCTGCGTAAGGCAAATGCTCGT
GAGGTAGCTCGTTATGAAAAAGCCTGA
Antitoxin
Download Length: 83 a.a. Molecular weight: 9139.49 Da Isoelectric Point: 4.5357
>AT235900 WP_249007833.1 NZ_CP092289:c1049563-1049315 [Marinobacter sp. M1C]
MTQPIYTEIAASISELKKNPMAAVSAGEGFPIVVLNRNKPAFYCVPADVYEAMLDRLDDQELARLVESRRSERSIPVSLN
EL
MTQPIYTEIAASISELKKNPMAAVSAGEGFPIVVLNRNKPAFYCVPADVYEAMLDRLDDQELARLVESRRSERSIPVSLN
EL
Download Length: 249 bp
>AT235900 NZ_LR134480:2383203-2383481 [Bordetella bronchiseptica]
ATGAAAAAGCCTGACCCCGAAAAGATTGACCGCGACAACCCCGAATGGACGGACGCGGAATTTCGGCGGGCCAAGCCGGC
CGCCGAAGTACTGCCCGAGTCGGTGCACGCGATGCTCGGCATTCGTCGCCGTGGGCCTCAAAAGACACCCACCAAACAGG
TCGTCACCATCCGGCTATCGCCTGACGTGGTAGAAGCCTTCAAGGCCTCCGGCACCGGTTGGCAGACTCGCGTGGATGCA
GCCCTGCGGGATTGGCTGAAGACGCACCAGCCTGGCTAG
ATGAAAAAGCCTGACCCCGAAAAGATTGACCGCGACAACCCCGAATGGACGGACGCGGAATTTCGGCGGGCCAAGCCGGC
CGCCGAAGTACTGCCCGAGTCGGTGCACGCGATGCTCGGCATTCGTCGCCGTGGGCCTCAAAAGACACCCACCAAACAGG
TCGTCACCATCCGGCTATCGCCTGACGTGGTAGAAGCCTTCAAGGCCTCCGGCACCGGTTGGCAGACTCGCGTGGATGCA
GCCCTGCGGGATTGGCTGAAGACGCACCAGCCTGGCTAG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|