Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafQ-relB/YafQ-RelB
Location 1045059..1045588 Replicon chromosome
Accession NZ_CP092289
Organism Marinobacter sp. M1C

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag MIH19_RS05015 Protein ID WP_249007825.1
Coordinates 1045059..1045331 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MIH19_RS05020 Protein ID WP_249007826.1
Coordinates 1045331..1045588 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MIH19_RS04955 (MIH19_04955) 1040088..1040324 - 237 WP_249007816.1 hypothetical protein -
MIH19_RS04960 (MIH19_04960) 1040577..1041008 - 432 WP_249007817.1 type II toxin-antitoxin system HicB family antitoxin -
MIH19_RS04965 (MIH19_04965) 1041049..1041231 - 183 WP_249007818.1 type II toxin-antitoxin system HicA family toxin -
MIH19_RS04970 (MIH19_04970) 1041336..1041878 - 543 WP_249007819.1 hypothetical protein -
MIH19_RS04975 (MIH19_04975) 1042013..1042279 + 267 WP_249007820.1 YlcI/YnfO family protein -
MIH19_RS04980 (MIH19_04980) 1042276..1042575 + 300 WP_249007821.1 type II toxin-antitoxin system RelE/ParE family toxin -
MIH19_RS04985 (MIH19_04985) 1042605..1042928 + 324 Protein_971 type II toxin-antitoxin system RelE/ParE family toxin -
MIH19_RS04990 (MIH19_04990) 1042930..1043232 + 303 WP_249007822.1 XRE family transcriptional regulator -
MIH19_RS04995 (MIH19_04995) 1043350..1043730 + 381 WP_249007823.1 helix-turn-helix transcriptional regulator -
MIH19_RS05000 (MIH19_05000) 1043762..1043881 - 120 Protein_974 type II toxin-antitoxin system RelE/ParE family toxin -
MIH19_RS05005 (MIH19_05005) 1044024..1044212 + 189 Protein_975 ATP-binding protein -
MIH19_RS05010 (MIH19_05010) 1044322..1044795 - 474 WP_249007824.1 outer membrane protein assembly factor BamE -
MIH19_RS05015 (MIH19_05015) 1045059..1045331 - 273 WP_249007825.1 type II toxin-antitoxin system YafQ family toxin Toxin
MIH19_RS05020 (MIH19_05020) 1045331..1045588 - 258 WP_249007826.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MIH19_RS05025 (MIH19_05025) 1045940..1046434 - 495 WP_249007827.1 MgtC/SapB family protein -
MIH19_RS22405 1046494..1046616 + 123 WP_283164099.1 hypothetical protein -
MIH19_RS05030 (MIH19_05030) 1046785..1047300 + 516 WP_249007828.1 sn-glycerol-3-phosphate transporter -
MIH19_RS05035 (MIH19_05035) 1047610..1047696 - 87 WP_249008946.1 type II toxin-antitoxin system HicB family antitoxin -
MIH19_RS05040 (MIH19_05040) 1047798..1047929 - 132 WP_249007829.1 type II toxin-antitoxin system HicA family toxin -
MIH19_RS05045 (MIH19_05045) 1048209..1048559 + 351 WP_249007830.1 DUF2784 domain-containing protein -
MIH19_RS05050 (MIH19_05050) 1048746..1049003 + 258 WP_249007831.1 helix-turn-helix transcriptional regulator -
MIH19_RS05055 (MIH19_05055) 1049035..1049325 - 291 WP_249007832.1 type II toxin-antitoxin system RelE/ParE family toxin -
MIH19_RS05060 (MIH19_05060) 1049315..1049563 - 249 WP_249007833.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
MIH19_RS05065 (MIH19_05065) 1049742..1049996 - 255 WP_249008947.1 type II toxin-antitoxin system RelE/ParE family toxin -
MIH19_RS05070 (MIH19_05070) 1050023..1050295 - 273 WP_249007834.1 CopG family ribbon-helix-helix protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1030151..1052171 22020


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(5-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-77)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10526.16 Da        Isoelectric Point: 10.2513

>T235899 WP_249007825.1 NZ_CP092289:c1045331-1045059 [Marinobacter sp. M1C]
VLTPVQSTQFKKDVKKARKRGKDLDKLKMSLSLLIRQAPLPEAYQDHPLRGNWKGYRDAHIEPDWLLLYRVTDKELQLAR
TGTHADLFQE

Download         Length: 273 bp

>T235899 NZ_LR134480:2086144-2086569 [Bordetella bronchiseptica]
ATGATCCTGCTCGACACCGACGTGCTGCTCGAGCCGCTGCGGCCGGCCCCCGACCCGGCCGTCGCGGCATGGCTGGATGC
CCAGCACGTCGAAACCCTGTACCTGGCCGCGCCCGGCGCGGCCGAAATCCAGCTCGGGCTGGCCCGCCTGCCGCGCGGCA
AGCGGGCCGAGGCCCTGCGCCACGAATTCGAGCGGCGCGTCCTGCCGCTGTTCATGGGCCATGTCCTGCCCTTCGACACG
GCCGCGGCCGATGCCTACGCCGCCGTCATGATGCGGGCCGCGGCGGCGGGCCATGCGCTGTGCGCAATCGATGGCTGCAT
CGCCGCCATCGCCACCGCGCACGGCCTGGCCATCGCCACGCGCCATCCGGCCAGGTTCGAGGCGGCCGGGCTCGCCGCCG
TCGATCCCTGGCACGCCGCCGCTTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9258.66 Da        Isoelectric Point: 5.8213

>AT235899 WP_249007826.1 NZ_CP092289:c1045588-1045331 [Marinobacter sp. M1C]
MNTDSVVRARIDSDTKARATAALDAMGLSVSDAIRLLMLKIADEQRLPFAVQVPNAKTVKAMEELEAGKGKRFSHEQALF
DDLGL

Download         Length: 258 bp

>AT235899 NZ_LR134480:2085908-2086147 [Bordetella bronchiseptica]
GTGTCTTCGATTACGGTAAGAAATGTTCCCGAGGAAGTGCATCGCGCCTTGCGCGTACGCGCGGCCACGCATGGGCGCAG
CACCGAGGCCGAGATCCGCGCCATCCTGGAAAACGCCGTGCTGCCCGATGGCCGCGTCAAGCTGGGCACCCTGCTCAGCC
ACATCGGCCGCGGCGCGCGCGGCATGGACCTGACCATCGAGCGCAATCCGGCGCCCGCCCGCCCGGCCAGTTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References