Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /BrnT(toxin) |
| Location | 4521178..4521685 | Replicon | chromosome |
| Accession | NZ_CP092288 | ||
| Organism | Marinobacter sp. M2C | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | MIH17_RS21240 | Protein ID | WP_249006763.1 |
| Coordinates | 4521512..4521685 (-) | Length | 58 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | MIH17_RS21235 | Protein ID | WP_249006762.1 |
| Coordinates | 4521178..4521432 (-) | Length | 85 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MIH17_RS21205 (MIH17_21205) | 4516492..4517340 | - | 849 | WP_249006756.1 | putative selenate ABC transporter substrate-binding protein | - |
| MIH17_RS21210 (MIH17_21210) | 4517620..4518258 | - | 639 | WP_249006757.1 | SGNH/GDSL hydrolase family protein | - |
| MIH17_RS21215 (MIH17_21215) | 4518649..4518978 | - | 330 | WP_249006758.1 | DHCW motif cupin fold protein | - |
| MIH17_RS21220 (MIH17_21220) | 4519078..4519341 | - | 264 | WP_249006759.1 | Txe/YoeB family addiction module toxin | - |
| MIH17_RS21225 (MIH17_21225) | 4519338..4519580 | - | 243 | WP_249006760.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| MIH17_RS21230 (MIH17_21230) | 4519820..4520767 | - | 948 | WP_249006761.1 | D-hexose-6-phosphate mutarotase | - |
| MIH17_RS21235 (MIH17_21235) | 4521178..4521432 | - | 255 | WP_249006762.1 | CopG family transcriptional regulator | Antitoxin |
| MIH17_RS21240 (MIH17_21240) | 4521512..4521685 | - | 174 | WP_249006763.1 | BrnT family toxin | Toxin |
| MIH17_RS21245 (MIH17_21245) | 4521815..4522231 | - | 417 | WP_249006764.1 | GFA family protein | - |
| MIH17_RS21250 (MIH17_21250) | 4522583..4522879 | - | 297 | WP_249006765.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| MIH17_RS21255 (MIH17_21255) | 4522879..4523133 | - | 255 | WP_249006766.1 | type II toxin-antitoxin system ParD family antitoxin | - |
| MIH17_RS21260 (MIH17_21260) | 4523327..4523626 | - | 300 | WP_249006767.1 | hypothetical protein | - |
| MIH17_RS21265 (MIH17_21265) | 4523747..4524229 | - | 483 | WP_249006768.1 | SgcJ/EcaC family oxidoreductase | - |
| MIH17_RS21270 (MIH17_21270) | 4524345..4524626 | - | 282 | WP_249006769.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| MIH17_RS21275 (MIH17_21275) | 4524623..4524895 | - | 273 | WP_249006770.1 | ribbon-helix-helix protein, CopG family | - |
| MIH17_RS21280 (MIH17_21280) | 4525099..4525344 | + | 246 | WP_249006771.1 | type II toxin-antitoxin system CcdA family antitoxin | - |
| MIH17_RS21285 (MIH17_21285) | 4525344..4525661 | + | 318 | WP_072795464.1 | CcdB family protein | - |
| MIH17_RS21290 (MIH17_21290) | 4525754..4526242 | - | 489 | WP_249006772.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 4518649..4567047 | 48398 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 58 a.a. Molecular weight: 6676.57 Da Isoelectric Point: 5.0495
>T235892 WP_249006763.1 NZ_CP092288:c4521685-4521512 [Marinobacter sp. M2C]
MDEFEFDETKSQTNLDKHGIDFVAARVLWKDPYLLEIRAKSEGEPRFVLIGKIGERH
MDEFEFDETKSQTNLDKHGIDFVAARVLWKDPYLLEIRAKSEGEPRFVLIGKIGERH
Download Length: 174 bp
>T235892 NZ_LR134478:c4315468-4315046 [Serratia plymuthica]
GTGGCCCAGTGGCGATGTAATGTCCGCATTTCCTGGCGCACCCAGTTACTCTCGCTGCTGACCCATGGCGTTCTGATCCT
GCTGATTCTGATTGCGCCTTGGCCGGAAGGCTACGGCCCGATCTGGCTGGTGATGCTGACGCTGGTGGTGTTTGAATGCA
TTCGCAGCCAGAAGCGCATTGCGTCACTGCAGGGCGAATTGCGCCTGCTGGCGAATAAGCGTTTGAGCTGGCACGGACAG
GAATGGTTGCTGGTAAAGCAACCCTGGATGCCGCGTTACGGAATTCTGCTGACGCTGCAGCCGATACAGGGCAAAAAGCC
CCGCCGGCTGTGGCTGGCCTCCGACAGCATGGGCAAAGCCGAATGGCGGCATCTGCGCCAGCTGTTGCAGTACCCGTCGG
CCGATGATGACGAGGAACCCTGA
GTGGCCCAGTGGCGATGTAATGTCCGCATTTCCTGGCGCACCCAGTTACTCTCGCTGCTGACCCATGGCGTTCTGATCCT
GCTGATTCTGATTGCGCCTTGGCCGGAAGGCTACGGCCCGATCTGGCTGGTGATGCTGACGCTGGTGGTGTTTGAATGCA
TTCGCAGCCAGAAGCGCATTGCGTCACTGCAGGGCGAATTGCGCCTGCTGGCGAATAAGCGTTTGAGCTGGCACGGACAG
GAATGGTTGCTGGTAAAGCAACCCTGGATGCCGCGTTACGGAATTCTGCTGACGCTGCAGCCGATACAGGGCAAAAAGCC
CCGCCGGCTGTGGCTGGCCTCCGACAGCATGGGCAAAGCCGAATGGCGGCATCTGCGCCAGCTGTTGCAGTACCCGTCGG
CCGATGATGACGAGGAACCCTGA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9814.09 Da Isoelectric Point: 5.8726
>AT235892 WP_249006762.1 NZ_CP092288:c4521432-4521178 [Marinobacter sp. M2C]
MKARDFDKKFEEGQDDIVDDLDLSTVRRVNQEQKRINVDFPAWVVESLDREAARIGVTRQSIIKVWLVERLQAESANKCV
TRTH
MKARDFDKKFEEGQDDIVDDLDLSTVRRVNQEQKRINVDFPAWVVESLDREAARIGVTRQSIIKVWLVERLQAESANKCV
TRTH
Download Length: 255 bp
>AT235892 NZ_LR134478:c4315715-4315449 [Serratia plymuthica]
ATGGATATTAATAATAAAGCACGTATTCACTGGGCCTGCCGCCGTGGCATGCGTGAGCTGGACATCTCAATCATGCCGTT
TTTCGAGCATGAGTACGATCGCTTGAATGACACAGACAAAGCGTTGTTTATCCGCCTGCTTGAAAGCGACGATCCCGATC
TGTTCAACTGGTTGATGAATCATGGCGCTCCGCAAGACAGTGAACTGCAGAGAATGGTGACACTGATTCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCGATGTAA
ATGGATATTAATAATAAAGCACGTATTCACTGGGCCTGCCGCCGTGGCATGCGTGAGCTGGACATCTCAATCATGCCGTT
TTTCGAGCATGAGTACGATCGCTTGAATGACACAGACAAAGCGTTGTTTATCCGCCTGCTTGAAAGCGACGATCCCGATC
TGTTCAACTGGTTGATGAATCATGGCGCTCCGCAAGACAGTGAACTGCAGAGAATGGTGACACTGATTCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCGATGTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|