Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | yoeB-relB/Txe-YefM |
| Location | 4519078..4519580 | Replicon | chromosome |
| Accession | NZ_CP092288 | ||
| Organism | Marinobacter sp. M2C | ||
Toxin (Protein)
| Gene name | yoeB | Uniprot ID | - |
| Locus tag | MIH17_RS21220 | Protein ID | WP_249006759.1 |
| Coordinates | 4519078..4519341 (-) | Length | 88 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | MIH17_RS21225 | Protein ID | WP_249006760.1 |
| Coordinates | 4519338..4519580 (-) | Length | 81 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MIH17_RS21195 (MIH17_21195) | 4514358..4515824 | - | 1467 | WP_249006754.1 | ABC transporter permease | - |
| MIH17_RS21200 (MIH17_21200) | 4515842..4516492 | - | 651 | WP_249006755.1 | ATP-binding cassette domain-containing protein | - |
| MIH17_RS21205 (MIH17_21205) | 4516492..4517340 | - | 849 | WP_249006756.1 | putative selenate ABC transporter substrate-binding protein | - |
| MIH17_RS21210 (MIH17_21210) | 4517620..4518258 | - | 639 | WP_249006757.1 | SGNH/GDSL hydrolase family protein | - |
| MIH17_RS21215 (MIH17_21215) | 4518649..4518978 | - | 330 | WP_249006758.1 | DHCW motif cupin fold protein | - |
| MIH17_RS21220 (MIH17_21220) | 4519078..4519341 | - | 264 | WP_249006759.1 | Txe/YoeB family addiction module toxin | Toxin |
| MIH17_RS21225 (MIH17_21225) | 4519338..4519580 | - | 243 | WP_249006760.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| MIH17_RS21230 (MIH17_21230) | 4519820..4520767 | - | 948 | WP_249006761.1 | D-hexose-6-phosphate mutarotase | - |
| MIH17_RS21235 (MIH17_21235) | 4521178..4521432 | - | 255 | WP_249006762.1 | CopG family transcriptional regulator | - |
| MIH17_RS21240 (MIH17_21240) | 4521512..4521685 | - | 174 | WP_249006763.1 | BrnT family toxin | - |
| MIH17_RS21245 (MIH17_21245) | 4521815..4522231 | - | 417 | WP_249006764.1 | GFA family protein | - |
| MIH17_RS21250 (MIH17_21250) | 4522583..4522879 | - | 297 | WP_249006765.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| MIH17_RS21255 (MIH17_21255) | 4522879..4523133 | - | 255 | WP_249006766.1 | type II toxin-antitoxin system ParD family antitoxin | - |
| MIH17_RS21260 (MIH17_21260) | 4523327..4523626 | - | 300 | WP_249006767.1 | hypothetical protein | - |
| MIH17_RS21265 (MIH17_21265) | 4523747..4524229 | - | 483 | WP_249006768.1 | SgcJ/EcaC family oxidoreductase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 4518649..4567047 | 48398 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 88 a.a. Molecular weight: 10073.76 Da Isoelectric Point: 10.2588
>T235891 WP_249006759.1 NZ_CP092288:c4519341-4519078 [Marinobacter sp. M2C]
VTWKLVYTKQAQKDAKKLAASSLKPKAQGLLALIAEDPYRRPPPFEKLIGDLAGAYSRRINIQHRVVYEVLEDERVVKVL
RLWSHYE
VTWKLVYTKQAQKDAKKLAASSLKPKAQGLLALIAEDPYRRPPPFEKLIGDLAGAYSRRINIQHRVVYEVLEDERVVKVL
RLWSHYE
Download Length: 264 bp
>T235891 NZ_LR134478:4246071-4246415 [Serratia plymuthica]
ATGTGGCAGGTCGTAACCGTCGAACGATTCGACGACTGGTTTTTATCACTGAACAGCGATGAACAAAAAAGCCTGTTGGC
AGGAATATTCAAATTGCAGGAATTCGGCCCGCTGTTGGCGCGTCCGCATGCCGACACTCTGCATTTTTCAGGCTCAATAA
GGCATCTTAAAGAGCTGCGCATTCAGCACCACGGCCGCCCGTTTCGAGTATTTTTCGCCTTTGATCCGCAACGGCAGGCG
GTACTGCTATGCGGTGGCGATAAAACCGGCGATAAACGCTTTTACCAGCGCCTGTTGCCTATCGCCGCCATGGAATTTTC
ACATTATCTGGCAACCCAGAGGTAA
ATGTGGCAGGTCGTAACCGTCGAACGATTCGACGACTGGTTTTTATCACTGAACAGCGATGAACAAAAAAGCCTGTTGGC
AGGAATATTCAAATTGCAGGAATTCGGCCCGCTGTTGGCGCGTCCGCATGCCGACACTCTGCATTTTTCAGGCTCAATAA
GGCATCTTAAAGAGCTGCGCATTCAGCACCACGGCCGCCCGTTTCGAGTATTTTTCGCCTTTGATCCGCAACGGCAGGCG
GTACTGCTATGCGGTGGCGATAAAACCGGCGATAAACGCTTTTACCAGCGCCTGTTGCCTATCGCCGCCATGGAATTTTC
ACATTATCTGGCAACCCAGAGGTAA
Antitoxin
Download Length: 81 a.a. Molecular weight: 9157.32 Da Isoelectric Point: 4.1317
>AT235891 WP_249006760.1 NZ_CP092288:c4519580-4519338 [Marinobacter sp. M2C]
MTGITATEARSNLYRLIDETAESHQPIVIMGKRNRAVLVSEEDWSAIQETLYLLSVPGMRESIREGMETPMDQCDEELNW
MTGITATEARSNLYRLIDETAESHQPIVIMGKRNRAVLVSEEDWSAIQETLYLLSVPGMRESIREGMETPMDQCDEELNW
Download Length: 243 bp
>AT235891 NZ_LR134478:4246421-4246723 [Serratia plymuthica]
ATGGCCAAGCCTTTATCAAATCTGATCGATAAACTCGATCCCACCGTCGTTGCGGCAGCCCGGCAAAAGGCGGAGAAAGA
AATTTTTGAACTGCGTCTGGCGATGCTGCGGGAAGAACTTGCGGTGTCTCAGGTCGAGCTGGCGAAACGGCTTGGCATCA
GCCAGCCGTCGGTCGCTAATCTGGAAAAGCGCGGTAGCGAAATCAAACTCTCTTCACTGAAACGCTACATTGAAGCCATG
GGCGGCACGCTTTCGTTAGAGGTTGAGCTGCCCAACGGCCAGCATCGGCGGATGACACTCTGA
ATGGCCAAGCCTTTATCAAATCTGATCGATAAACTCGATCCCACCGTCGTTGCGGCAGCCCGGCAAAAGGCGGAGAAAGA
AATTTTTGAACTGCGTCTGGCGATGCTGCGGGAAGAACTTGCGGTGTCTCAGGTCGAGCTGGCGAAACGGCTTGGCATCA
GCCAGCCGTCGGTCGCTAATCTGGAAAAGCGCGGTAGCGAAATCAAACTCTCTTCACTGAAACGCTACATTGAAGCCATG
GGCGGCACGCTTTCGTTAGAGGTTGAGCTGCCCAACGGCCAGCATCGGCGGATGACACTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|