Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) shpA-brnA/BrnT_toxin-BrnA
Location 1116272..1116782 Replicon chromosome
Accession NZ_CP092288
Organism Marinobacter sp. M2C

Toxin (Protein)


Gene name shpA Uniprot ID -
Locus tag MIH17_RS05405 Protein ID WP_249007892.1
Coordinates 1116272..1116544 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag MIH17_RS05410 Protein ID WP_249007893.1
Coordinates 1116528..1116782 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MIH17_RS05385 (MIH17_05385) 1111988..1113388 + 1401 WP_249007888.1 threonine synthase -
MIH17_RS05390 (MIH17_05390) 1113394..1115124 + 1731 WP_249007889.1 single-stranded-DNA-specific exonuclease RecJ -
MIH17_RS05395 (MIH17_05395) 1115190..1115525 - 336 WP_249007890.1 putative addiction module antidote protein -
MIH17_RS05400 (MIH17_05400) 1115538..1115834 - 297 WP_249007891.1 type II toxin-antitoxin system RelE/ParE family toxin -
MIH17_RS05405 (MIH17_05405) 1116272..1116544 + 273 WP_249007892.1 BrnT family toxin Toxin
MIH17_RS05410 (MIH17_05410) 1116528..1116782 + 255 WP_249007893.1 BrnA antitoxin family protein Antitoxin
MIH17_RS05415 (MIH17_05415) 1116841..1118250 + 1410 WP_249007894.1 plasmid pRiA4b ORF-3 family protein -
MIH17_RS05420 (MIH17_05420) 1118402..1118668 + 267 WP_249007895.1 type II toxin-antitoxin system HicA family toxin -
MIH17_RS05425 (MIH17_05425) 1118665..1119006 + 342 WP_249007896.1 type II toxin-antitoxin system HicB family antitoxin -
MIH17_RS05430 (MIH17_05430) 1119141..1121288 - 2148 WP_249007897.1 flagellin -
MIH17_RS05435 (MIH17_05435) 1121457..1121711 + 255 WP_249007898.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-82)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(37-77)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10694.23 Da        Isoelectric Point: 5.7237

>T235885 WP_249007892.1 NZ_CP092288:1116272-1116544 [Marinobacter sp. M2C]
MYFEWDDSKNAANISKHGIDFRDAIDMFNHPMLTAIDECFMYGEERWTAIGLMREMVGVVVYTERRESVVRIISARKATR
REVRLYEQNI

Download         Length: 273 bp

>T235885 NZ_LR134478:2055989-2056085 [Serratia plymuthica]
AACAAGCCCTGCACAAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9964.32 Da        Isoelectric Point: 5.8560

>AT235885 WP_249007893.1 NZ_CP092288:1116528-1116782 [Marinobacter sp. M2C]
MSKTSKTDWKRLTEMEDDAIDTSDISELDDKFFQNAELLIPTKQPVTLRIDEDVLVWFKAQGRGYQTRINKLLRHYMESQ
VTKR

Download         Length: 255 bp

>AT235885 NZ_LR134478:c2056093-2055945 [Serratia plymuthica]
AACAAGTTAAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAA
GTTGGCATTTTGTGCAGGGCTTGTTCAGCCATGCACTTTAAGAGTAGCTTACCGCGCTAGTTTTGCCAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References