Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-YafN |
| Location | 1050716..1051244 | Replicon | chromosome |
| Accession | NZ_CP092288 | ||
| Organism | Marinobacter sp. M2C | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | MIH17_RS05060 | Protein ID | WP_249007832.1 |
| Coordinates | 1050716..1051006 (-) | Length | 97 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | MIH17_RS05065 | Protein ID | WP_249007833.1 |
| Coordinates | 1050996..1051244 (-) | Length | 83 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MIH17_RS05015 (MIH17_05015) | 1046003..1046476 | - | 474 | WP_249007824.1 | outer membrane protein assembly factor BamE | - |
| MIH17_RS05020 (MIH17_05020) | 1046740..1047012 | - | 273 | WP_249007825.1 | type II toxin-antitoxin system YafQ family toxin | - |
| MIH17_RS05025 (MIH17_05025) | 1047012..1047269 | - | 258 | WP_249007826.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | - |
| MIH17_RS05030 (MIH17_05030) | 1047621..1048115 | - | 495 | WP_249007827.1 | MgtC/SapB family protein | - |
| MIH17_RS22395 | 1048175..1048297 | + | 123 | WP_283164099.1 | hypothetical protein | - |
| MIH17_RS05035 (MIH17_05035) | 1048466..1048981 | + | 516 | WP_249007828.1 | sn-glycerol-3-phosphate transporter | - |
| MIH17_RS05040 (MIH17_05040) | 1049291..1049377 | - | 87 | WP_249008946.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| MIH17_RS05045 (MIH17_05045) | 1049479..1049610 | - | 132 | WP_249007829.1 | type II toxin-antitoxin system HicA family toxin | - |
| MIH17_RS05050 (MIH17_05050) | 1049848..1050240 | + | 393 | WP_283164144.1 | DUF2784 domain-containing protein | - |
| MIH17_RS05055 (MIH17_05055) | 1050427..1050684 | + | 258 | WP_249007831.1 | helix-turn-helix transcriptional regulator | - |
| MIH17_RS05060 (MIH17_05060) | 1050716..1051006 | - | 291 | WP_249007832.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| MIH17_RS05065 (MIH17_05065) | 1050996..1051244 | - | 249 | WP_249007833.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| MIH17_RS05070 (MIH17_05070) | 1051423..1051677 | - | 255 | WP_249008947.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| MIH17_RS05075 (MIH17_05075) | 1051704..1051976 | - | 273 | WP_249007834.1 | CopG family ribbon-helix-helix protein | - |
| MIH17_RS05080 (MIH17_05080) | 1052137..1052721 | - | 585 | WP_249007835.1 | histidine phosphatase family protein | - |
| MIH17_RS05085 (MIH17_05085) | 1052754..1052960 | - | 207 | WP_249007836.1 | hypothetical protein | - |
| MIH17_RS05090 (MIH17_05090) | 1053109..1053852 | - | 744 | WP_249007837.1 | ParA family protein | - |
| MIH17_RS05095 (MIH17_05095) | 1054185..1054895 | + | 711 | Protein_994 | acyl-CoA dehydrogenase family protein | - |
| MIH17_RS05100 (MIH17_05100) | 1055122..1055307 | + | 186 | WP_249007838.1 | hypothetical protein | - |
| MIH17_RS05105 (MIH17_05105) | 1055349..1056149 | - | 801 | WP_249007839.1 | dienelactone hydrolase family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 11097.04 Da Isoelectric Point: 10.7120
>T235883 WP_249007832.1 NZ_CP092288:c1051006-1050716 [Marinobacter sp. M2C]
MSSKYALEFKPSALKEWKKLAPALQAQFKKKLKQRLDDPHVPPDALSDLKNCYKIKLRSAGYRLVYEVENERIVVTVVAV
GKRERGAVYSRAHRRI
MSSKYALEFKPSALKEWKKLAPALQAQFKKKLKQRLDDPHVPPDALSDLKNCYKIKLRSAGYRLVYEVENERIVVTVVAV
GKRERGAVYSRAHRRI
Download Length: 291 bp
>T235883 NZ_LR134478:c1706891-1706607 [Serratia plymuthica]
ATGACTTATAGCCTTGAATTCGAAGAACATGCACTAAAGGAATTTAAGAAACTGGCCCCGGTACTTCGGGATCAATTCAA
GAAAAAACTGGCAACAGTATTAGAAAATCCCTGTATTCCCGCCAATAGACTCTCTGGCCTATCGGATTGCTATAAAATAA
AACTTAAGGCTTCCGGTTACCGTCTGGTCTATCGCGTCATCGACGAGGAGATTGTGGTGCTGGTACTTTCGATAGGTAAG
CGTGAGCGCTCAGAGGCCTATACGGCTGCCAAAAAACGCCTTTAA
ATGACTTATAGCCTTGAATTCGAAGAACATGCACTAAAGGAATTTAAGAAACTGGCCCCGGTACTTCGGGATCAATTCAA
GAAAAAACTGGCAACAGTATTAGAAAATCCCTGTATTCCCGCCAATAGACTCTCTGGCCTATCGGATTGCTATAAAATAA
AACTTAAGGCTTCCGGTTACCGTCTGGTCTATCGCGTCATCGACGAGGAGATTGTGGTGCTGGTACTTTCGATAGGTAAG
CGTGAGCGCTCAGAGGCCTATACGGCTGCCAAAAAACGCCTTTAA
Antitoxin
Download Length: 83 a.a. Molecular weight: 9139.49 Da Isoelectric Point: 4.5357
>AT235883 WP_249007833.1 NZ_CP092288:c1051244-1050996 [Marinobacter sp. M2C]
MTQPIYTEIAASISELKKNPMAAVSAGEGFPIVVLNRNKPAFYCVPADVYEAMLDRLDDQELARLVESRRSERSIPVSLN
EL
MTQPIYTEIAASISELKKNPMAAVSAGEGFPIVVLNRNKPAFYCVPADVYEAMLDRLDDQELARLVESRRSERSIPVSLN
EL
Download Length: 249 bp
>AT235883 NZ_LR134478:c1707132-1706881 [Serratia plymuthica]
ATGATCGTTCAGCCTATCCTCGCAAACTCAGCCGTCAGCATCAGTGATTTTAAAAAATCGCCTAACACTGCGCTCAAAGA
AGCCAACGGGCAACCTGTGGCAGTACTTACCAATGGAAAGATCTCCGGCTATTACGTCTCTCCGGAAACGTGGGAAGCAA
TCTCTGAATACCTGGAAGATATCGAACTCGCAAAAATAGCCCGCTCACGGATGAGTGGCAAACGTATTAAGGTCAATCTG
GATGACTTATAG
ATGATCGTTCAGCCTATCCTCGCAAACTCAGCCGTCAGCATCAGTGATTTTAAAAAATCGCCTAACACTGCGCTCAAAGA
AGCCAACGGGCAACCTGTGGCAGTACTTACCAATGGAAAGATCTCCGGCTATTACGTCTCTCCGGAAACGTGGGAAGCAA
TCTCTGAATACCTGGAAGATATCGAACTCGCAAAAATAGCCCGCTCACGGATGAGTGGCAAACGTATTAAGGTCAATCTG
GATGACTTATAG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|