Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafQ-relB/YafQ-RelB
Location 1653553..1654082 Replicon chromosome
Accession NZ_CP092284
Organism Marinobacter sp. M3C

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag MIH18_RS07595 Protein ID WP_249007825.1
Coordinates 1653810..1654082 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MIH18_RS07590 Protein ID WP_249007826.1
Coordinates 1653553..1653810 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MIH18_RS07540 (MIH18_07535) 1648850..1649122 + 273 WP_249007834.1 CopG family ribbon-helix-helix protein -
MIH18_RS07545 (MIH18_07540) 1649149..1649403 + 255 WP_249008947.1 type II toxin-antitoxin system RelE/ParE family toxin -
MIH18_RS07550 (MIH18_07545) 1649582..1649830 + 249 WP_249007833.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
MIH18_RS07555 (MIH18_07550) 1649820..1650110 + 291 WP_249014239.1 type II toxin-antitoxin system RelE/ParE family toxin -
MIH18_RS07560 (MIH18_07555) 1650142..1650399 - 258 WP_249014240.1 helix-turn-helix transcriptional regulator -
MIH18_RS07565 (MIH18_07560) 1650586..1650978 - 393 WP_283164144.1 DUF2784 domain-containing protein -
MIH18_RS07570 (MIH18_07565) 1651167..1651346 + 180 WP_249014602.1 type II toxin-antitoxin system HicA family toxin -
MIH18_RS07575 (MIH18_07570) 1651412..1651534 + 123 Protein_1490 type II toxin-antitoxin system HicB family antitoxin -
MIH18_RS07580 (MIH18_07575) 1651844..1652359 - 516 WP_249007828.1 sn-glycerol-3-phosphate transporter -
MIH18_RS07585 (MIH18_07580) 1652707..1653201 + 495 WP_249007827.1 MgtC/SapB family protein -
MIH18_RS07590 (MIH18_07585) 1653553..1653810 + 258 WP_249007826.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MIH18_RS07595 (MIH18_07590) 1653810..1654082 + 273 WP_249007825.1 type II toxin-antitoxin system YafQ family toxin Toxin
MIH18_RS07600 (MIH18_07595) 1654346..1654819 + 474 WP_249007824.1 outer membrane protein assembly factor BamE -
MIH18_RS07605 (MIH18_07600) 1654929..1655117 - 189 Protein_1496 ATP-binding protein -
MIH18_RS07610 (MIH18_07605) 1655260..1655379 + 120 Protein_1497 type II toxin-antitoxin system RelE/ParE family toxin -
MIH18_RS07615 (MIH18_07610) 1655411..1655791 - 381 WP_249007823.1 helix-turn-helix transcriptional regulator -
MIH18_RS07620 (MIH18_07615) 1655909..1656211 - 303 WP_249007822.1 XRE family transcriptional regulator -
MIH18_RS07625 (MIH18_07620) 1656213..1656536 - 324 Protein_1500 type II toxin-antitoxin system RelE/ParE family toxin -
MIH18_RS07630 (MIH18_07625) 1656566..1656865 - 300 WP_249014241.1 type II toxin-antitoxin system RelE/ParE family toxin -
MIH18_RS07635 (MIH18_07630) 1656862..1657128 - 267 WP_249007820.1 YlcI/YnfO family protein -
MIH18_RS07640 (MIH18_07635) 1657263..1657805 + 543 WP_249007819.1 hypothetical protein -
MIH18_RS07645 (MIH18_07640) 1657910..1658092 + 183 WP_249007818.1 type II toxin-antitoxin system HicA family toxin -
MIH18_RS07650 (MIH18_07645) 1658133..1658564 + 432 WP_249014242.1 type II toxin-antitoxin system HicB family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(5-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-77)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10526.16 Da        Isoelectric Point: 10.2513

>T235872 WP_249007825.1 NZ_CP092284:1653810-1654082 [Marinobacter sp. M3C]
VLTPVQSTQFKKDVKKARKRGKDLDKLKMSLSLLIRQAPLPEAYQDHPLRGNWKGYRDAHIEPDWLLLYRVTDKELQLAR
TGTHADLFQE

Download         Length: 273 bp

>T235872 NZ_LR134475:836170-836580 [Klebsiella aerogenes]
GTGGTCCTGTGGCAATCTGATTTACGTATTTCCTGGCGTTCGCAGTGGTTCTCGCTGCTGCTGCACGGGGTGGTGGCGGC
GATAGTGCTGCTCATGCCCTGGCCGTTAAGCTACACCCCGATTTGGCTCCTGTTGCTATCGCTGGTGGTGTTTGACTGCG
TGCGCAGCCAGCGGCGGATCCACGCCTGCCAGGGAGAAATTAAGCTGTTGATCGATTCCCGTTTACGGTGGCAAAAAACG
GAATGGGATATCGTCGGGACGCCATGGGTTATCAGCAGCGGGATGCTGCTGCGCCTGAAGCATGCGGAAACCGGCCGTAG
CCAGCATTTGTGGGTGGCGGCGGATAGCATGGATGCGGGGGAATGGCGGGATTTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCACGACTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9258.66 Da        Isoelectric Point: 5.8213

>AT235872 WP_249007826.1 NZ_CP092284:1653553-1653810 [Marinobacter sp. M3C]
MNTDSVVRARIDSDTKARATAALDAMGLSVSDAIRLLMLKIADEQRLPFAVQVPNAKTVKAMEELEAGKGKRFSHEQALF
DDLGL

Download         Length: 258 bp

>AT235872 NZ_LR134475:835923-836189 [Klebsiella aerogenes]
ATGGACATTAACAACAAAGCTCGCATCCACTGGGCATGCCGCCGCGGTATGCGCGAACTCGATATCTCCATCATGCCGTT
TTTCGAGTATGAGTACGACACGCTCAGCGATGACGACAAGCGCCTGTTCATCCGTTTGCTGGAGAACGATGATCCGGATC
TGTTTAACTGGCTGATGAATCACGGCAAGCCGGCAGATGCGCAACTTCAACGGATGATTAATTTAATCCAGACTCGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References