Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-YafN |
| Location | 1649582..1650110 | Replicon | chromosome |
| Accession | NZ_CP092284 | ||
| Organism | Marinobacter sp. M3C | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | MIH18_RS07555 | Protein ID | WP_249014239.1 |
| Coordinates | 1649820..1650110 (+) | Length | 97 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | MIH18_RS07550 | Protein ID | WP_249007833.1 |
| Coordinates | 1649582..1649830 (+) | Length | 83 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MIH18_RS07510 (MIH18_07505) | 1644678..1645478 | + | 801 | WP_249007839.1 | dienelactone hydrolase family protein | - |
| MIH18_RS07515 (MIH18_07510) | 1645519..1645704 | - | 186 | WP_249007838.1 | hypothetical protein | - |
| MIH18_RS07520 (MIH18_07515) | 1645931..1646641 | - | 711 | Protein_1479 | acyl-CoA dehydrogenase family protein | - |
| MIH18_RS07525 (MIH18_07520) | 1646974..1647717 | + | 744 | WP_249007837.1 | ParA family protein | - |
| MIH18_RS07530 (MIH18_07525) | 1647866..1648072 | + | 207 | WP_249007836.1 | hypothetical protein | - |
| MIH18_RS07535 (MIH18_07530) | 1648105..1648689 | + | 585 | WP_249007835.1 | histidine phosphatase family protein | - |
| MIH18_RS07540 (MIH18_07535) | 1648850..1649122 | + | 273 | WP_249007834.1 | CopG family ribbon-helix-helix protein | - |
| MIH18_RS07545 (MIH18_07540) | 1649149..1649403 | + | 255 | WP_249008947.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| MIH18_RS07550 (MIH18_07545) | 1649582..1649830 | + | 249 | WP_249007833.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| MIH18_RS07555 (MIH18_07550) | 1649820..1650110 | + | 291 | WP_249014239.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| MIH18_RS07560 (MIH18_07555) | 1650142..1650399 | - | 258 | WP_249014240.1 | helix-turn-helix transcriptional regulator | - |
| MIH18_RS07565 (MIH18_07560) | 1650586..1650978 | - | 393 | WP_283164144.1 | DUF2784 domain-containing protein | - |
| MIH18_RS07570 (MIH18_07565) | 1651167..1651346 | + | 180 | WP_249014602.1 | type II toxin-antitoxin system HicA family toxin | - |
| MIH18_RS07575 (MIH18_07570) | 1651412..1651534 | + | 123 | Protein_1490 | type II toxin-antitoxin system HicB family antitoxin | - |
| MIH18_RS07580 (MIH18_07575) | 1651844..1652359 | - | 516 | WP_249007828.1 | sn-glycerol-3-phosphate transporter | - |
| MIH18_RS07585 (MIH18_07580) | 1652707..1653201 | + | 495 | WP_249007827.1 | MgtC/SapB family protein | - |
| MIH18_RS07590 (MIH18_07585) | 1653553..1653810 | + | 258 | WP_249007826.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | - |
| MIH18_RS07595 (MIH18_07590) | 1653810..1654082 | + | 273 | WP_249007825.1 | type II toxin-antitoxin system YafQ family toxin | - |
| MIH18_RS07600 (MIH18_07595) | 1654346..1654819 | + | 474 | WP_249007824.1 | outer membrane protein assembly factor BamE | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 11098.03 Da Isoelectric Point: 10.6072
>T235871 WP_249014239.1 NZ_CP092284:1649820-1650110 [Marinobacter sp. M3C]
MSSKYALEFKPSALKEWKKLAPALQAQFKKKLKQRLDDPHVPPDALSDLKNCYKIKLRSAGYRLVYEVEDERIVVTVVAV
GKRERGAVYSRAHRRI
MSSKYALEFKPSALKEWKKLAPALQAQFKKKLKQRLDDPHVPPDALSDLKNCYKIKLRSAGYRLVYEVEDERIVVTVVAV
GKRERGAVYSRAHRRI
Download Length: 291 bp
>T235871 NZ_LR134475:310451-310819 [Klebsiella aerogenes]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCGGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCTGC
AGCGGGGCAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGCGGATGA
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCGGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCTGC
AGCGGGGCAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGCGGATGA
Antitoxin
Download Length: 83 a.a. Molecular weight: 9139.49 Da Isoelectric Point: 4.5357
>AT235871 WP_249007833.1 NZ_CP092284:1649582-1649830 [Marinobacter sp. M3C]
MTQPIYTEIAASISELKKNPMAAVSAGEGFPIVVLNRNKPAFYCVPADVYEAMLDRLDDQELARLVESRRSERSIPVSLN
EL
MTQPIYTEIAASISELKKNPMAAVSAGEGFPIVVLNRNKPAFYCVPADVYEAMLDRLDDQELARLVESRRSERSIPVSLN
EL
Download Length: 249 bp
>AT235871 NZ_LR134475:310233-310454 [Klebsiella aerogenes]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTGCCTGTGAC
AATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGGCGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTGCCTGTGAC
AATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGGCGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|