Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YefM
Location 795740..796320 Replicon chromosome
Accession NZ_CP092284
Organism Marinobacter sp. M3C

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MIH18_RS03525 Protein ID WP_249006798.1
Coordinates 796018..796320 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MIH18_RS03520 Protein ID WP_249012538.1
Coordinates 795740..796021 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MIH18_RS03495 (MIH18_03500) 791222..791857 + 636 WP_249013947.1 hypothetical protein -
MIH18_RS03500 (MIH18_03505) 791946..792323 + 378 WP_249013948.1 hypothetical protein -
MIH18_RS03505 (MIH18_03510) 792486..794057 + 1572 WP_249013949.1 transposase -
MIH18_RS03510 (MIH18_03515) 794298..794882 + 585 WP_249013950.1 hypothetical protein -
MIH18_RS03515 (MIH18_03520) 794982..795566 + 585 WP_249013951.1 hypothetical protein -
MIH18_RS03520 (MIH18_03525) 795740..796021 + 282 WP_249012538.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MIH18_RS03525 (MIH18_03530) 796018..796320 + 303 WP_249006798.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MIH18_RS03530 (MIH18_03535) 796463..796741 + 279 WP_249008559.1 type II toxin-antitoxin system RelE/ParE family toxin -
MIH18_RS03535 (MIH18_03540) 796752..797066 + 315 WP_249008558.1 HigA family addiction module antitoxin -
MIH18_RS03540 (MIH18_03545) 797444..798091 + 648 WP_283164826.1 glutathione S-transferase -
MIH18_RS03545 (MIH18_03550) 798285..799331 - 1047 WP_249008557.1 ACP S-malonyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 785411..813696 28285
- inside Integron - - 785131..791857 6726
- inside Integron - - 794982..796741 1759


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-74)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11496.18 Da        Isoelectric Point: 4.6583

>T235868 WP_249006798.1 NZ_CP092284:796018-796320 [Marinobacter sp. M3C]
MKIIWSPLALERIEDISRYIAEDNPDAALQWVNDLFATVERLADFPKSGRMVPEVGAPRIRELIFGTYRVIYSVKDQVNI
LTVRRSSQLLRMSEVGDDET

Download         Length: 303 bp

>T235868 NZ_LR134451:c93062-92688 [Tsukamurella tyrosinosolvens]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10647.17 Da        Isoelectric Point: 6.7300

>AT235868 WP_249012538.1 NZ_CP092284:795740-796021 [Marinobacter sp. M3C]
MSRVRVDEDIRPLSEFRAGVATFIKQLHETRRPMVLTQRGRGVAVLLGVHEYERMQERLEMLEEVYKAEEQIASGDGVAH
EDAKARVLSRLGQ

Download         Length: 282 bp

>AT235868 NZ_LR134451:c93328-93074 [Tsukamurella tyrosinosolvens]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References