Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /BrnT(toxin) |
| Location | 4523674..4524181 | Replicon | chromosome |
| Accession | NZ_CP092283 | ||
| Organism | Marinobacter sp. M4C | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | MIH16_RS21245 | Protein ID | WP_249006763.1 |
| Coordinates | 4524008..4524181 (-) | Length | 58 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | MIH16_RS21240 | Protein ID | WP_249006762.1 |
| Coordinates | 4523674..4523928 (-) | Length | 85 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MIH16_RS21210 (MIH16_21210) | 4518988..4519836 | - | 849 | WP_249006756.1 | putative selenate ABC transporter substrate-binding protein | - |
| MIH16_RS21215 (MIH16_21215) | 4520116..4520754 | - | 639 | WP_249006757.1 | SGNH/GDSL hydrolase family protein | - |
| MIH16_RS21220 (MIH16_21220) | 4521145..4521474 | - | 330 | WP_249006758.1 | DHCW motif cupin fold protein | - |
| MIH16_RS21225 (MIH16_21225) | 4521574..4521837 | - | 264 | WP_249006759.1 | Txe/YoeB family addiction module toxin | - |
| MIH16_RS21230 (MIH16_21230) | 4521834..4522076 | - | 243 | WP_249006760.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| MIH16_RS21235 (MIH16_21235) | 4522316..4523263 | - | 948 | WP_249006761.1 | D-hexose-6-phosphate mutarotase | - |
| MIH16_RS21240 (MIH16_21240) | 4523674..4523928 | - | 255 | WP_249006762.1 | CopG family transcriptional regulator | Antitoxin |
| MIH16_RS21245 (MIH16_21245) | 4524008..4524181 | - | 174 | WP_249006763.1 | BrnT family toxin | Toxin |
| MIH16_RS21250 (MIH16_21250) | 4524311..4524727 | - | 417 | WP_249006764.1 | GFA family protein | - |
| MIH16_RS21255 (MIH16_21255) | 4525079..4525375 | - | 297 | WP_249006765.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| MIH16_RS21260 (MIH16_21260) | 4525375..4525629 | - | 255 | WP_249006766.1 | type II toxin-antitoxin system ParD family antitoxin | - |
| MIH16_RS21265 (MIH16_21265) | 4526243..4526725 | - | 483 | WP_249006768.1 | SgcJ/EcaC family oxidoreductase | - |
| MIH16_RS21270 (MIH16_21270) | 4526841..4527122 | - | 282 | WP_249006769.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| MIH16_RS21275 (MIH16_21275) | 4527119..4527391 | - | 273 | WP_249006770.1 | ribbon-helix-helix protein, CopG family | - |
| MIH16_RS21280 (MIH16_21280) | 4527595..4527840 | + | 246 | WP_249006771.1 | type II toxin-antitoxin system CcdA family antitoxin | - |
| MIH16_RS21285 (MIH16_21285) | 4527840..4528157 | + | 318 | WP_072795464.1 | CcdB family protein | - |
| MIH16_RS21290 (MIH16_21290) | 4528250..4528738 | - | 489 | WP_249006772.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 4521574..4530131 | 8557 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 58 a.a. Molecular weight: 6676.57 Da Isoelectric Point: 5.0495
>T235861 WP_249006763.1 NZ_CP092283:c4524181-4524008 [Marinobacter sp. M4C]
MDEFEFDETKSQTNLDKHGIDFVAARVLWKDPYLLEIRAKSEGEPRFVLIGKIGERH
MDEFEFDETKSQTNLDKHGIDFVAARVLWKDPYLLEIRAKSEGEPRFVLIGKIGERH
Download Length: 174 bp
>T235861 NZ_LR134442:585443-585703 [Propionibacterium australiense]
GTGCTCCTCGTCTGGGACGAGAACGCCTGGGACGACTATCTGTGGTGGCGGGCCCAGGACCGCACGGGGCTCAAGCGCAT
CAACCGTCTCATCGTCGACGTGGCGCGCAACGGCAACGAGGGCATCGGCAAGCCCGAGGCACTGCGGCACGGCCTCGCCG
GCTACTGGTCGCGGCGGATCACCGACGAGCACCGGCTCGTCTACAGGATCGACGGTGAACGCATCCTCGTCGCTGCCTGT
CGCTACCACTACGGACGTTGA
GTGCTCCTCGTCTGGGACGAGAACGCCTGGGACGACTATCTGTGGTGGCGGGCCCAGGACCGCACGGGGCTCAAGCGCAT
CAACCGTCTCATCGTCGACGTGGCGCGCAACGGCAACGAGGGCATCGGCAAGCCCGAGGCACTGCGGCACGGCCTCGCCG
GCTACTGGTCGCGGCGGATCACCGACGAGCACCGGCTCGTCTACAGGATCGACGGTGAACGCATCCTCGTCGCTGCCTGT
CGCTACCACTACGGACGTTGA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9814.09 Da Isoelectric Point: 5.8726
>AT235861 WP_249006762.1 NZ_CP092283:c4523928-4523674 [Marinobacter sp. M4C]
MKARDFDKKFEEGQDDIVDDLDLSTVRRVNQEQKRINVDFPAWVVESLDREAARIGVTRQSIIKVWLVERLQAESANKCV
TRTH
MKARDFDKKFEEGQDDIVDDLDLSTVRRVNQEQKRINVDFPAWVVESLDREAARIGVTRQSIIKVWLVERLQAESANKCV
TRTH
Download Length: 255 bp
>AT235861 NZ_LR134442:585183-585440 [Propionibacterium australiense]
ATGAAGACGATCAGCTACACCGAATCACGGGCGCGGTACGCCGAGGTGCTTGATGCGGTCACCGACAACCGCGAGGAGGT
CATCATCACCCGGGCCGGGCACGAGCCAGTCGTCATGATCTCGCTCGCCGATTACGAATCGCTGCGCGAGACGGCCTGTC
TGATGCGTTCCCCGGAGAACTCCAGGCGGCTGCTCGACGCGGTGGAACGTCTCGAGTCCGGTGGCGGGCGCCCGCACGAG
CTCCTCCCCGGGGACTGA
ATGAAGACGATCAGCTACACCGAATCACGGGCGCGGTACGCCGAGGTGCTTGATGCGGTCACCGACAACCGCGAGGAGGT
CATCATCACCCGGGCCGGGCACGAGCCAGTCGTCATGATCTCGCTCGCCGATTACGAATCGCTGCGCGAGACGGCCTGTC
TGATGCGTTCCCCGGAGAACTCCAGGCGGCTGCTCGACGCGGTGGAACGTCTCGAGTCCGGTGGCGGGCGCCCGCACGAG
CTCCTCCCCGGGGACTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|