Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1051423..1051976 Replicon chromosome
Accession NZ_CP092283
Organism Marinobacter sp. M4C

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MIH16_RS05070 Protein ID WP_249008947.1
Coordinates 1051423..1051677 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MIH16_RS05075 Protein ID WP_249007834.1
Coordinates 1051704..1051976 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MIH16_RS05020 (MIH16_05020) 1046740..1047012 - 273 WP_249007825.1 type II toxin-antitoxin system YafQ family toxin -
MIH16_RS05025 (MIH16_05025) 1047012..1047269 - 258 WP_249007826.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
MIH16_RS05030 (MIH16_05030) 1047621..1048115 - 495 WP_249007827.1 MgtC/SapB family protein -
MIH16_RS22400 1048175..1048297 + 123 WP_283164099.1 hypothetical protein -
MIH16_RS05035 (MIH16_05035) 1048466..1048981 + 516 WP_249007828.1 sn-glycerol-3-phosphate transporter -
MIH16_RS05040 (MIH16_05040) 1049291..1049377 - 87 WP_249008946.1 type II toxin-antitoxin system HicB family antitoxin -
MIH16_RS05045 (MIH16_05045) 1049479..1049610 - 132 WP_249007829.1 type II toxin-antitoxin system HicA family toxin -
MIH16_RS05050 (MIH16_05050) 1049848..1050240 + 393 WP_283164144.1 DUF2784 domain-containing protein -
MIH16_RS05055 (MIH16_05055) 1050427..1050684 + 258 WP_249007831.1 helix-turn-helix transcriptional regulator -
MIH16_RS05060 (MIH16_05060) 1050716..1051006 - 291 WP_249007832.1 type II toxin-antitoxin system RelE/ParE family toxin -
MIH16_RS05065 (MIH16_05065) 1050996..1051244 - 249 WP_249007833.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
MIH16_RS05070 (MIH16_05070) 1051423..1051677 - 255 WP_249008947.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MIH16_RS05075 (MIH16_05075) 1051704..1051976 - 273 WP_249007834.1 CopG family ribbon-helix-helix protein Antitoxin
MIH16_RS05080 (MIH16_05080) 1052137..1052721 - 585 WP_249007835.1 histidine phosphatase family protein -
MIH16_RS05085 (MIH16_05085) 1052754..1052960 - 207 WP_249007836.1 hypothetical protein -
MIH16_RS05090 (MIH16_05090) 1053109..1053852 - 744 WP_249007837.1 ParA family protein -
MIH16_RS05095 (MIH16_05095) 1054185..1054895 + 711 Protein_994 acyl-CoA dehydrogenase family protein -
MIH16_RS05100 (MIH16_05100) 1055122..1055307 + 186 WP_249007838.1 hypothetical protein -
MIH16_RS05105 (MIH16_05105) 1055349..1056149 - 801 WP_249007839.1 dienelactone hydrolase family protein -
MIH16_RS05110 (MIH16_05110) 1056309..1056881 + 573 WP_249007840.1 glutathione S-transferase N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9508.87 Da        Isoelectric Point: 7.3581

>T235853 WP_249008947.1 NZ_CP092283:c1051677-1051423 [Marinobacter sp. M4C]
MERCRKFLAAKAPEASRRAGQTIERHFLFLETATGIGRPFAEMPELRELVIAFGNSGYVALYHHEPADDAVYVLAFRHQK
EAGF

Download         Length: 255 bp

>T235853 NZ_LR134418:c249383-249096 [Legionella adelaidensis]
ATGCATATTATAACTAGAAGAAGAATTACCGAAGCAAAAGCACTTTATCCACAATGCGCATCAGCTCTAGCTGGGTGGTT
GAAAGTTGTTGAGGAGAATGAGTTTAAGAGTTTTGGTGAGTTAAAGGCTGTATTTAATAGTATTGATAGAGTGGGTGGCT
TATTTGTCTTTGATATTGGGGGTAATAAACTCCGTTTGATAGCCAGCATCCATTTTAATCGGAAAAAATTGTATATACGT
CATATCTTAACCCATCAAGAATATGACAAAAATAAGTGGAAGGAGTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10545.71 Da        Isoelectric Point: 6.9791

>AT235853 WP_249007834.1 NZ_CP092283:c1051976-1051704 [Marinobacter sp. M4C]
MATSLKIDNTLKSRVHHIANQRRRSPHWIMLEAIQQYVEREEARESFKQEALASWSAYKETGRHLTGQEARAWLNTWGND
DEKAAPECHE

Download         Length: 273 bp

>AT235853 NZ_LR134418:c249093-248668 [Legionella adelaidensis]
ATGACTGCTTTAGCATACAACGATTATTTAGAAGAGACAATCCAACACTGGAAACATATCTCCCCCATTATTCATGATCC
TCAAAATGATGATGAATATGAGAAACTTGCCAGCATGCTCGATCAATTATTAGATGTTGTTGGTGACAATGAATCTCATG
ATTTAATGGGGTTGGTTGATGTAATCAGCCATATGATCACTATGTATGATGAAAATCATGATGAACAACTACAAAAAGGA
AGTGGCATTGATGCTTTAAAATTTCTCATGGAGCAGCATGGTTTAGATCAAAGTGATCTTAAAGATGAAATTGGAAGCCA
AGGTGTTGTTTCTGAAATTCTAAACGGGAAACGTCAACTTAATCTCTCCCATATTAAGAAATTGGCAAAGCGATTTCATG
TTACTCCAGCTACTTTTATAGATTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References