Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafQ-relB/YafQ-RelB
Location 1046740..1047269 Replicon chromosome
Accession NZ_CP092283
Organism Marinobacter sp. M4C

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag MIH16_RS05020 Protein ID WP_249007825.1
Coordinates 1046740..1047012 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MIH16_RS05025 Protein ID WP_249007826.1
Coordinates 1047012..1047269 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MIH16_RS04960 (MIH16_04960) 1041769..1042005 - 237 WP_249007816.1 hypothetical protein -
MIH16_RS04965 (MIH16_04965) 1042258..1042689 - 432 WP_249007817.1 type II toxin-antitoxin system HicB family antitoxin -
MIH16_RS04970 (MIH16_04970) 1042730..1042912 - 183 WP_249007818.1 type II toxin-antitoxin system HicA family toxin -
MIH16_RS04975 (MIH16_04975) 1043017..1043559 - 543 WP_249007819.1 hypothetical protein -
MIH16_RS04980 (MIH16_04980) 1043694..1043960 + 267 WP_249007820.1 YlcI/YnfO family protein -
MIH16_RS04985 (MIH16_04985) 1043957..1044256 + 300 WP_249007821.1 type II toxin-antitoxin system RelE/ParE family toxin -
MIH16_RS04990 (MIH16_04990) 1044286..1044609 + 324 Protein_972 type II toxin-antitoxin system RelE/ParE family toxin -
MIH16_RS04995 (MIH16_04995) 1044611..1044913 + 303 WP_249007822.1 XRE family transcriptional regulator -
MIH16_RS05000 (MIH16_05000) 1045031..1045411 + 381 WP_249007823.1 helix-turn-helix transcriptional regulator -
MIH16_RS05005 (MIH16_05005) 1045443..1045562 - 120 Protein_975 type II toxin-antitoxin system RelE/ParE family toxin -
MIH16_RS05010 (MIH16_05010) 1045705..1045893 + 189 Protein_976 ATP-binding protein -
MIH16_RS05015 (MIH16_05015) 1046003..1046476 - 474 WP_249007824.1 outer membrane protein assembly factor BamE -
MIH16_RS05020 (MIH16_05020) 1046740..1047012 - 273 WP_249007825.1 type II toxin-antitoxin system YafQ family toxin Toxin
MIH16_RS05025 (MIH16_05025) 1047012..1047269 - 258 WP_249007826.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MIH16_RS05030 (MIH16_05030) 1047621..1048115 - 495 WP_249007827.1 MgtC/SapB family protein -
MIH16_RS22400 1048175..1048297 + 123 WP_283164099.1 hypothetical protein -
MIH16_RS05035 (MIH16_05035) 1048466..1048981 + 516 WP_249007828.1 sn-glycerol-3-phosphate transporter -
MIH16_RS05040 (MIH16_05040) 1049291..1049377 - 87 WP_249008946.1 type II toxin-antitoxin system HicB family antitoxin -
MIH16_RS05045 (MIH16_05045) 1049479..1049610 - 132 WP_249007829.1 type II toxin-antitoxin system HicA family toxin -
MIH16_RS05050 (MIH16_05050) 1049848..1050240 + 393 WP_283164144.1 DUF2784 domain-containing protein -
MIH16_RS05055 (MIH16_05055) 1050427..1050684 + 258 WP_249007831.1 helix-turn-helix transcriptional regulator -
MIH16_RS05060 (MIH16_05060) 1050716..1051006 - 291 WP_249007832.1 type II toxin-antitoxin system RelE/ParE family toxin -
MIH16_RS05065 (MIH16_05065) 1050996..1051244 - 249 WP_249007833.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
MIH16_RS05070 (MIH16_05070) 1051423..1051677 - 255 WP_249008947.1 type II toxin-antitoxin system RelE/ParE family toxin -
MIH16_RS05075 (MIH16_05075) 1051704..1051976 - 273 WP_249007834.1 CopG family ribbon-helix-helix protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(5-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-77)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10526.16 Da        Isoelectric Point: 10.2513

>T235851 WP_249007825.1 NZ_CP092283:c1047012-1046740 [Marinobacter sp. M4C]
VLTPVQSTQFKKDVKKARKRGKDLDKLKMSLSLLIRQAPLPEAYQDHPLRGNWKGYRDAHIEPDWLLLYRVTDKELQLAR
TGTHADLFQE

Download         Length: 273 bp

>T235851 NZ_LR134406:c3069533-3069198 [Arachnia propionica]
CTGACCGCCGACGAACCCTTCGGGGTGTCCGAACTGATCTTGTCGGGTTTTCTGCGAATCGTGACGAACCACCGGGTCTA
CCGCGAACCGACTTCGCCGCAGGTGGCGCTGGACTTCTGTCAGACGGTGTTGAGCGCCTCGTCGGCGGTCCGCATCCGCC
CAGGGCGGGGGCATTGGCGCATCTTCGAGAGCCTGTGCCGGAACCTCGGGGCGCGCGGCAACGTGGTTCCCGACGCCTAT
CTGGCGGCCATGGCCATTGAGGCCGACGCCACCTTCATCACCATGGACGCGGGATTCGCCCGGTTTCCTGGACTCACCTG
GCGGCGCGCTCTGTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9258.66 Da        Isoelectric Point: 5.8213

>AT235851 WP_249007826.1 NZ_CP092283:c1047269-1047012 [Marinobacter sp. M4C]
MNTDSVVRARIDSDTKARATAALDAMGLSVSDAIRLLMLKIADEQRLPFAVQVPNAKTVKAMEELEAGKGKRFSHEQALF
DDLGL

Download         Length: 258 bp

>AT235851 NZ_LR134406:c3069857-3069609 [Arachnia propionica]
ATGCGCACCACGGTGAATCTGGACGATGAACTGCTGCGCCGGGCCAAGGAGCGGGCGGCTCGTCAGGGAAGGACCTTGAG
CGAGGTGGTCTCCGACGCCCTACGGGTTTCACTCGCTGAGCAGGCCGGGCCACGCCGTGAGGTCACCCTGCCCACCTTCG
GCGGCAGCGGGTTGAAGCCGGGCGTCGACCTCGAGGACAAGGACGCCCTCGCAGCGCTTCTCGGCGAAGACGATCGTGCT
GCTCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References