Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 2184759..2185284 Replicon chromosome
Accession NZ_CP092264
Organism Levilactobacillus brevis strain YSJ3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MD222_RS10935 Protein ID WP_043023228.1
Coordinates 2184759..2185022 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MD222_RS10940 Protein ID WP_043023227.1
Coordinates 2185015..2185284 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MD222_RS10925 (MD222_10925) 2181608..2182660 - 1053 WP_087609247.1 alpha/beta hydrolase fold domain-containing protein -
MD222_RS10930 (MD222_10930) 2182722..2184101 - 1380 WP_043022289.1 MFS transporter -
MD222_RS10935 (MD222_10935) 2184759..2185022 - 264 WP_043023228.1 Txe/YoeB family addiction module toxin Toxin
MD222_RS10940 (MD222_10940) 2185015..2185284 - 270 WP_043023227.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MD222_RS10945 (MD222_10945) 2185813..2187456 + 1644 WP_239309539.1 peptide ABC transporter substrate-binding protein -
MD222_RS10950 (MD222_10950) 2187647..2188147 - 501 WP_225350422.1 hypothetical protein -
MD222_RS10955 (MD222_10955) 2188164..2188652 - 489 WP_047021140.1 hypothetical protein -
MD222_RS10960 (MD222_10960) 2188887..2189885 - 999 WP_108477375.1 LacI family DNA-binding transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10259.70 Da        Isoelectric Point: 9.8184

>T235848 WP_043023228.1 NZ_CP092264:c2185022-2184759 [Levilactobacillus brevis]
MNKLFTENAWQDYLWLLKNDRRALKRVNLLLQDISRTPFSGIGKPESLHGDFTGYWSRRVNEKDRLVYAADEKTITILAC
RTHYGDK

Download         Length: 264 bp

>T235848 NZ_LR134406:c2759671-2759309 [Arachnia propionica]
GTGATCCTCGTCGACACCTCCGTCTGGATCGACCACTTCCGTCGCAGCGACCTGCGTCTGGTGCGCCTGCTGCGCGGAGA
CGAGGCAGGCTGCCACGCCATGGTCATCGGGGAGCTGTCGCTGAGTTCCATGCCCGCCCGCACGGTGCGGATGTCATACC
TGTCGAACCTGTACCGGTTCCCCAGCCTCCACGACGACGAACTGCTGCACCTCGTCGAGACCAGACGGTTGTGGGGTCGC
GGCCTCAGCCTGGTTGACGTCAACCTCATCGGCTCCGTCCTGGTGGTCCCGGGGGCCTGCCTGTGGACCCGCGACAAACG
CCTCCGGGCGGTCGCCAAGGAGCTGGAGATCGCCTTCGAGTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10329.45 Da        Isoelectric Point: 4.8500

>AT235848 WP_043023227.1 NZ_CP092264:c2185284-2185015 [Levilactobacillus brevis]
MEATTYTDFRKNLKKYMDKATGDFEPITITRKDHQNAVLISEEEYNNMLENRYILDNPTNREWLQASLKQAKDGQVAAHH
LVTPSADDE

Download         Length: 270 bp

>AT235848 NZ_LR134406:c2759874-2759668 [Arachnia propionica]
ATGAGAACCACCGTTACCCTGGACGACGACTTGGTGGCACGCGCCCAGGAACTGACCGGCGTCAAGGAACGTTCCGTCCT
GCTCCGTGAGGGCCTCGAGACGCTGATTCGCGTCGAGAGCGCCCGCCGCTTGGCCGCGCTCGGCGGCACCGAACCGGAGG
CGCAGATATCGTCGCGGACCCGGGACCTCGGGGACCTCGCGAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References