235786

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 142199..142908 Replicon plasmid unnamed2
Accession NZ_CP092188
Organism Deinococcus sp. KNUC1210

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag MF271_RS01200 Protein ID WP_239048380.1
Coordinates 142199..142525 (-) Length 109 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag MF271_RS01205 Protein ID WP_239048283.1
Coordinates 142522..142908 (-) Length 129 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MF271_RS01170 (MF271_01170) 137645..138313 + 669 WP_239048277.1 hypothetical protein -
MF271_RS01175 (MF271_01175) 138354..138668 + 315 WP_239048278.1 helix-turn-helix transcriptional regulator -
MF271_RS01180 (MF271_01180) 138854..139300 - 447 WP_239048279.1 hypothetical protein -
MF271_RS01185 (MF271_01185) 139454..139732 + 279 WP_239048280.1 helix-turn-helix transcriptional regulator -
MF271_RS01190 (MF271_01190) 140118..140810 - 693 WP_239048281.1 HAD hydrolase family protein -
MF271_RS01195 (MF271_01195) 141082..141381 + 300 WP_239048282.1 hypothetical protein -
MF271_RS01200 (MF271_01200) 142199..142525 - 327 WP_239048380.1 hypothetical protein Toxin
MF271_RS01205 (MF271_01205) 142522..142908 - 387 WP_239048283.1 excisionase family DNA-binding protein Antitoxin
MF271_RS01210 (MF271_01210) 143036..143728 + 693 Protein_137 alpha/beta hydrolase -
MF271_RS01215 (MF271_01215) 143844..145427 - 1584 WP_255807565.1 ABC transporter ATP-binding protein -
MF271_RS01220 (MF271_01220) 145653..147404 - 1752 WP_239048286.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..170208 170208


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Helix-turn-helix domain, group 17

(60-105)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12202.92 Da        Isoelectric Point: 4.3885

>T235786 WP_239048380.1 NZ_CP092188:c142525-142199 [Deinococcus sp. KNUC1210]
MTLVTALYDAGVLYPSLIRNLLVHLATSGLVAARWTEQIQEEWSRNLLQDRPELTPERLARTRRLMDAAVPDALVEDDQA
LIELERFEQVGLIQTAEALASPSNYRIT

Download         Length: 327 bp

>T235786 NZ_LR134354:1832019-1832342 [Bifidobacterium longum subsp. infantis]
ATGAAACGAGGTGAGATTCGGACGTTGCAGGCCGATGGCTACGCCAGCAAGCCACGGCCGGTTGTCATCGTGCAGAGCGA
TGCCGTCGATCGGTTCGATTCCGTCATCACTTGTCTGCTGACCTCATACGATTCCTCCGACATCGACACGCGGGTCCGAT
TGGAACCAAGTCCGGAGAACGGCCTGAACAAAGTGAGTTACGTGATGACGGACAAGATCGTCACCGTCGACCGCAAACTG
CTGGGATACCAAGTCGGCGTGGTTGATGATGCAGCCATGGCGAATATCGGCCGTCAGCTCATGCGGGTTCTAGGTTTGCT
GTGA

Antitoxin


Download         Length: 129 a.a.        Molecular weight: 14108.24 Da        Isoelectric Point: 5.1875

>AT235786 WP_239048283.1 NZ_CP092188:c142908-142522 [Deinococcus sp. KNUC1210]
MTAPFIPTPDDTQAAQLQLDMLRAQAGRLPVRLAEVLDGLLQELAAGRAVQVITLEEEISTQQAAELLNVSRPYLVKLVE
SGALPHRKVGPRRRLHLQDVLAYRARLEAQRQAALQALADDLQELGLD

Download         Length: 387 bp

>AT235786 NZ_LR134354:1831787-1832032 [Bifidobacterium longum subsp. infantis]
ATGAGCATGCAGATTGCCACGCGAGTTGATGACGAGCAGGCTGCGTTGTTTAAGGAGACGACCAGGCAGCTGGGTACCAC
CCCGGCCGATGCCCTGCGTATGTTCATCAGCGCGTTCAATGATTACCGTGGGTTCCCCTATGAGGTGCGTTTGCCACGAA
ATGACGTGGAGCCGTTTGCGTCCGAGCGGGACGCTACTGAGTATGCCAGTCGTCTCGCCTTGAGGATGTCCGATGAAACG
AGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References