235777

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 3457114..3457636 Replicon chromosome
Accession NZ_CP092184
Organism Serratia marcescens strain YHYF1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MF265_RS16765 Protein ID WP_239043696.1
Coordinates 3457355..3457636 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MF265_RS16760 Protein ID WP_239043695.1
Coordinates 3457114..3457365 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MF265_RS16730 (MF265_16730) 3452858..3453049 - 192 Protein_3263 RHS repeat-associated core domain-containing protein -
MF265_RS16735 (MF265_16735) 3453681..3454718 - 1038 WP_239043690.1 RHS repeat-associated core domain-containing protein -
MF265_RS16740 (MF265_16740) 3455049..3455237 - 189 WP_239043691.1 hypothetical protein -
MF265_RS16745 (MF265_16745) 3455410..3455739 - 330 WP_239043692.1 type II toxin-antitoxin system RelE/ParE family toxin -
MF265_RS16750 (MF265_16750) 3455708..3455944 - 237 WP_239043693.1 ParD-like family protein -
MF265_RS16755 (MF265_16755) 3456129..3456779 - 651 WP_239043694.1 ORF6N domain-containing protein -
MF265_RS16760 (MF265_16760) 3457114..3457365 + 252 WP_239043695.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MF265_RS16765 (MF265_16765) 3457355..3457636 + 282 WP_239043696.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MF265_RS16770 (MF265_16770) 3457777..3458196 - 420 WP_239043697.1 antiterminator Q family protein -
MF265_RS16775 (MF265_16775) 3458248..3458505 - 258 WP_239043698.1 hypothetical protein -
MF265_RS16780 (MF265_16780) 3458511..3458696 - 186 WP_239043699.1 hypothetical protein -
MF265_RS16785 (MF265_16785) 3458973..3459497 - 525 WP_239043700.1 hypothetical protein -
MF265_RS16790 (MF265_16790) 3459494..3459745 - 252 WP_239043701.1 DUF4222 domain-containing protein -
MF265_RS16795 (MF265_16795) 3460731..3460874 + 144 WP_239044587.1 ash family protein -
MF265_RS16800 (MF265_16800) 3460882..3461238 + 357 Protein_3277 phage antirepressor N-terminal domain-containing protein -
MF265_RS16805 (MF265_16805) 3461750..3462133 + 384 WP_239043702.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3441280..3467533 26253


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10930.71 Da        Isoelectric Point: 10.6469

>T235777 WP_239043696.1 NZ_CP092184:3457355-3457636 [Serratia marcescens]
MTYKLKFDSRALKEWRKLGDPIREQLKKKLAERLDNPHVPAARLSGRTNRYKIKLRSSGYRLVYEVNDNEITLLVIAIGK
RDGDKVYELADKR

Download         Length: 282 bp

>T235777 NZ_LR134352:220095-220463 [Nocardia asteroides]
GTGACCTGGGAGATTGTCCTGCATCCGGAGGTGGAGTCATGGTTCTTGGCAATCTGCGGCACGGACCCCGAGACGGGTGA
CCTGATCGAGCGGGCAATCGATCACCTCGCATCGGAAGGACCGAGCCTGGGCCGACCGCTGGTCGACCGCATCAAAGGCA
GCCGATATCACAATATGAAGGAGTTACGGCCGGCCTCGACCGGCACGACCGAGGTCCGGATACTGTTCGCCTTCGACCCC
GCCCGTGCCGCTGCGATGCTGGTGGCCGGGGACAAATCCAATTTCTGGCAGGGTTGGTACAGCGAGGCGATACCGCTGGC
CGACAAACGCTTCACCGAGCACCTGGAAGCGTTGAAGGAGCAGTCATGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9122.21 Da        Isoelectric Point: 3.9147

>AT235777 WP_239043695.1 NZ_CP092184:3457114-3457365 [Serratia marcescens]
MTYQILTTTAASITDLKKNPMGTVADGEGEAVAILNRNEPAFYCVPPALYAYYQELAEDAALNHIADERLKDAEFVDVNI
NDL

Download         Length: 252 bp

>AT235777 NZ_LR134352:220460-220792 [Nocardia asteroides]
ATGAGCACCGAATTCAGCAAGTGGACCGACGTCAAAGCCAGGGCCCGGCAGCAGGATCCGAGGTCGGAAGCGGAGCAGAC
GGCAGGCGCGCTTCGCGCGGACGAGCGCCACGAGTCGTACCTGCGCGGACATCAGCTCGCGGAAATTCGCAAAGCCATGG
GAATGACCCAGGTGGCGCTCGCCGAAGCCCTCGGAGTCACACAGGCACGGGTGTCGAAGATCGAGCGAGGCGAGATCTCG
GGGATAGACGCGATTCGGGCGTATGTGACCGCACTCGGCGGATCGGTCGATGTGGTCGTGCGGCTTGGCGATCGGACCTG
GAACGTAGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References