235767

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1787739..1788264 Replicon chromosome
Accession NZ_CP092184
Organism Serratia marcescens strain YHYF1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MF265_RS08635 Protein ID WP_015377296.1
Coordinates 1787739..1788023 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8B4GIN1
Locus tag MF265_RS08640 Protein ID WP_004928423.1
Coordinates 1788013..1788264 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MF265_RS08610 (MF265_08610) 1782999..1784132 + 1134 WP_033640832.1 putrescine ABC transporter ATP-binding subunit PotG -
MF265_RS08615 (MF265_08615) 1784157..1785119 + 963 WP_016928361.1 putrescine ABC transporter permease PotH -
MF265_RS08620 (MF265_08620) 1785116..1785961 + 846 WP_016928360.1 putrescine ABC transporter permease PotI -
MF265_RS08625 (MF265_08625) 1786066..1786545 + 480 WP_028127974.1 YbjO family protein -
MF265_RS08630 (MF265_08630) 1786615..1787742 + 1128 WP_239044402.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
MF265_RS08635 (MF265_08635) 1787739..1788023 - 285 WP_015377296.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MF265_RS08640 (MF265_08640) 1788013..1788264 - 252 WP_004928423.1 prevent-host-death protein Antitoxin
MF265_RS08645 (MF265_08645) 1788366..1789100 - 735 WP_016928355.1 arginine ABC transporter substrate-binding protein -
MF265_RS08650 (MF265_08650) 1789300..1789968 - 669 WP_033637817.1 arginine ABC transporter permease ArtM -
MF265_RS08655 (MF265_08655) 1789968..1790684 - 717 WP_028127976.1 arginine ABC transporter permease ArtQ -
MF265_RS08660 (MF265_08660) 1790694..1791425 - 732 WP_004928409.1 arginine ABC transporter substrate-binding protein -
MF265_RS08665 (MF265_08665) 1791458..1792186 - 729 WP_016928352.1 arginine ABC transporter ATP-binding protein ArtP -
MF265_RS08670 (MF265_08670) 1792450..1792992 - 543 WP_049299045.1 lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10803.94 Da        Isoelectric Point: 10.6941

>T235767 WP_015377296.1 NZ_CP092184:c1788023-1787739 [Serratia marcescens]
MTYKLEFEEHALKEFKKLSPVIREQFKKKLASVLVNPHIPANKLAGLPDCYKIKLRASGFRLVYRVMETEIVVLVLSVGK
RERSAAYTAAKKRL

Download         Length: 285 bp

>T235767 NZ_LR134351:1641702-1641797 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9108.39 Da        Isoelectric Point: 4.5203

>AT235767 WP_004928423.1 NZ_CP092184:c1788264-1788013 [Serratia marcescens]
MTVQPILADSAVSISDFKKSPNAALKEAQGQPVAVLTNGKISGYYVSPETWEAIAEYLEDIELAEIVRSRMNGKRIKVNL
DDL

Download         Length: 252 bp

>AT235767 NZ_LR134351:c1641882-1641825 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A8B4GIN1

References