Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1381691..1382255 Replicon chromosome
Accession NZ_CP092182
Organism Alcaligenes faecalis strain T17

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MF263_RS06320 Protein ID WP_239055311.1
Coordinates 1381929..1382255 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MF263_RS06315 Protein ID WP_239055310.1
Coordinates 1381691..1381942 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MF263_RS06290 (MF263_06290) 1377833..1378168 - 336 WP_239055307.1 flagellar protein FliT -
MF263_RS06295 (MF263_06295) 1378247..1378678 - 432 WP_026484537.1 flagellar export chaperone FliS -
MF263_RS06300 (MF263_06300) 1378685..1380073 - 1389 WP_239055308.1 flagellar filament capping protein FliD -
MF263_RS06305 (MF263_06305) 1380163..1380564 - 402 WP_239055309.1 flagellar protein FlaG -
MF263_RS06310 (MF263_06310) 1380802..1381563 + 762 WP_197314352.1 RNA polymerase sigma factor FliA -
MF263_RS06315 (MF263_06315) 1381691..1381942 + 252 WP_239055310.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
MF263_RS06320 (MF263_06320) 1381929..1382255 + 327 WP_239055311.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MF263_RS06325 (MF263_06325) 1382604..1383779 - 1176 WP_239055312.1 FliC/FljB family flagellin -
MF263_RS06330 (MF263_06330) 1384238..1386253 - 2016 WP_239055313.1 PhoX family phosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(13-92)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-72)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12465.60 Da        Isoelectric Point: 10.2255

>T235760 WP_239055311.1 NZ_CP092182:1381929-1382255 [Alcaligenes faecalis]
MSSSERQPTKYKLKFLPEALQERGRLDGSVKTTFKTLLRKRLDALRVPGSALRGDLQHCYKIKLLKQGYRLVYTVEDDVL
VVLVLAVNKREDMAVYRVAIQRLSEDLD

Download         Length: 327 bp

>T235760 NZ_LR134348:1203236-1203529 [Bifidobacterium breve]
ATGCTCAAACCGGATTACACAGCGGCATTCCAGCGAGATATCAAGAAACTCAAACGCAAGCACGCTGATTTACGCCCGCT
GAAAGAAGTCATTCGTCTGGTGCTTGAGGACACGGCGGACTCCAAGGAAGCATTGAGGCGTAGGCATCGCGCCCACACAC
TTACCGGTGATCTAAACGGCGTACTGGAATGCCACATCGGCAATGCCGGCGACTGGCTGCTTCTATGGATTCGCGATGAT
GGTACCGCCATGTTCATGCGAACCGGCAGCCATGACGAACTGTTGGGCAGATAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9548.94 Da        Isoelectric Point: 5.1133

>AT235760 WP_239055310.1 NZ_CP092182:1381691-1381942 [Alcaligenes faecalis]
MDAIYADYSISMSEFKKNPAQVLRTAGEKPVAVLHHNRPAFYMVTPRLFEALVEEMANRDLDELVRRRQAVKDTAVEVDL
EQL

Download         Length: 252 bp

>AT235760 NZ_LR134348:1202963-1203232 [Bifidobacterium breve]
GTGAGCATGGCATCCGTCACAGTCCGCGTGGATGCGGACACCAAGCAGAAAGCCGCAAACATAGCCGAGGATCTCGGTCT
GGACTTGTCTTCGGTCACCCGCGCCTTCTACAAGCAGATTGTCCGGGAGAGGCGCATTCCTCTAAACCTTTCCTATACGA
CCGTGCCGCCTGAAACCATGGAGGCCCTTGACGAGGCGAAAAACAGGCTCGCCGACGGCAAACCTCGTTTCAACAGTGCC
GATGAGATGTTCGATTCGTTGGGAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References