Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2779375..2779900 Replicon chromosome
Accession NZ_CP092123
Organism Marinobacterium sediminicola strain 1.7287

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LN244_RS12615 Protein ID WP_239040136.1
Coordinates 2779375..2779659 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LN244_RS12620 Protein ID WP_239040137.1
Coordinates 2779649..2779900 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LN244_RS12590 (LN244_12590) 2775430..2776038 + 609 WP_239040131.1 response regulator transcription factor -
LN244_RS12595 (LN244_12595) 2776035..2777339 - 1305 WP_239040132.1 hypothetical protein -
LN244_RS12600 (LN244_12600) 2777812..2778309 + 498 WP_239040133.1 peptidylprolyl isomerase -
LN244_RS12605 (LN244_12605) 2778388..2778669 + 282 WP_239040134.1 peptidylprolyl isomerase -
LN244_RS12610 (LN244_12610) 2778788..2779135 + 348 WP_239040135.1 FKBP-type peptidyl-prolyl cis-trans isomerase -
LN244_RS12615 (LN244_12615) 2779375..2779659 - 285 WP_239040136.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LN244_RS12620 (LN244_12620) 2779649..2779900 - 252 WP_239040137.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LN244_RS12625 (LN244_12625) 2780143..2782938 - 2796 WP_239040138.1 DEAD/DEAH box helicase family protein -
LN244_RS12630 (LN244_12630) 2782949..2784874 - 1926 WP_239040139.1 site-specific DNA-methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(11-77)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11085.06 Da        Isoelectric Point: 10.4271

>T235734 WP_239040136.1 NZ_CP092123:c2779659-2779375 [Marinobacterium sediminicola]
MTYKIKFIPAALKEWKKLAPSLRDQLKKKLSERAENPHVPASRLRGYESVYKIKMKTAGYRLVYEVEDDEIVIYVLAVGK
RERDAVYKKLAERR

Download         Length: 285 bp

>T235734 NZ_LR134335:3545843-3546139 [Yersinia enterocolitica subsp. palearctica]
ATGGAGAAACGGACTCCGCATACTCGTTTACTAAAAGTAAAAGAATTGGTATTGAAAGGGAATGTTAAATCGACTCGAAC
TGCCAGAGATGGCGCTGAAGAGCTGGGGCTGAGTTTTAGGGATATGTGTGATGTAGTTTGCGAACTGACTAGCGCCGATT
TTTATAAAAGTATGACGACACATCAAGATCATACGATTTGGCAGGATGTTTACCGCCCCATGCTTTCGTGCGGTAGAGTT
TATTTGAAAATCACGGTTATCGATGATGTTTTGATTGTCTCGTTTAAGGAGCTTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9329.51 Da        Isoelectric Point: 4.1813

>AT235734 WP_239040137.1 NZ_CP092123:c2779900-2779649 [Marinobacterium sediminicola]
MQQVLANCSASISELKKNPTALLKESGGETIAILNHNKPAAYLVPAETYEWMMDQLEDQALSQLVEERRQQRDQAIEVSL
DDL

Download         Length: 252 bp

>AT235734 NZ_LR134335:3546139-3546537 [Yersinia enterocolitica subsp. palearctica]
ATGATGAAATGCCCAGTTTGTGGTGGTGCAGAATTAATCCACGAAGCGCGTGACGTCCCCTTTACCTATAAAGGGCGTAA
GTTCATCGTCGAAGGCGTGATAGGACAACATTGCCCGGCATGCGGTGAAACAATCATGACTGAAGCTGAGTCCGATACCT
ATGCCGCAAAAACAATGCTTTTGCGAAAAATGGTTAATACAGAATCGATTGCACCCGCATATATTGTGCAGGTGCGAAAA
AAATTGGGTCTAAACCAGCGGGAAGCTAGTGAGATTTTTGGCGGTGGAGTGAATGCTTTTTCGCGTTACGAAAAGGGTAA
GGCGTTGCCACACCGATCAACGATAAAATTGTTGCAAGTACTTGATAAATATCCTGAGTTATTGAATGAAATCAGGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References