Detailed information of TA system TA235715

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1760801..1761366
• Replicon: chromosome
• Accession: NZ_CP092107
• Organism: Vibrio sp. JC009

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: L3Q72_RS22790
• Protein ID: WP_275132846.1
• Coordinates: 1761079..1761366 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: L3Q72_RS22785
• Protein ID: WP_275132845.1
• Coordinates: 1760801..1761082 (+)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L3Q72_RS22770 (L3Q72_22750)	1756405..1757313	+	909	WP_275132842.1	alpha/beta hydrolase	-
L3Q72_RS22775 (L3Q72_22755)	1758184..1759197	+	1014	WP_275132843.1	hypothetical protein	-
L3Q72_RS22780 (L3Q72_22760)	1759735..1760328	+	594	WP_275132844.1	Fic family protein	-
L3Q72_RS22785 (L3Q72_22765)	1760801..1761082	+	282	WP_275132845.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
L3Q72_RS22790 (L3Q72_22770)	1761079..1761366	+	288	WP_275132846.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
L3Q72_RS22795 (L3Q72_22775)	1761494..1761913	-	420	WP_275132847.1	YlcI/YnfO family protein	-
L3Q72_RS22800 (L3Q72_22780)	1761998..1762309	-	312	WP_275132848.1	hypothetical protein	-
L3Q72_RS22805 (L3Q72_22785)	1762306..1763484	-	1179	WP_275132849.1	site-specific integrase	-
L3Q72_RS22810 (L3Q72_22790)	1763496..1763708	-	213	WP_275132850.1	hypothetical protein	-
L3Q72_RS22815 (L3Q72_22795)	1763826..1764041	+	216	WP_275132851.1	helix-turn-helix transcriptional regulator	-
L3Q72_RS22825 (L3Q72_22805)	1764502..1765419	-	918	WP_275132852.1	pseudouridine-5'-phosphate glycosidase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1717601..1761913	44312

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (10-74)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10922.67 Da
• Isoelectric Point: 5.6851

>T235715 WP_275132846.1 NZ_CP092107:1761079-1761366 [Vibrio sp. JC009]
MKVVWSPLALQKLGDAAEFISLDNPSAARKWVDEVFDKAELLASMPEMGRMVPEMPNTNYREVIFGHYRIIYSISHEIRV
LTVRNCRQILTDDAL

Nucleotide

• Length: 288 bp

>T235715 NZ_LR134334:4493364-4493546 [Pseudomonas chlororaphis]
ATGCGCAGTCGGGAACTGATCAGGATGATCGAGGAGGACGGGTGGTATCTGATCGCGGTCAAAGGCAGTCATCACCAGTA
CAAGCATCTGCACAAGCCGGGGCGGGTCACTATCCCTCACCCGGATGCGGATCTGCCCAGGGGCACGATCCACAGCATCT
TGAAACAGGCGGGCCTGAAATGA

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10457.97 Da
• Isoelectric Point: 5.1881

>AT235715 WP_275132845.1 NZ_CP092107:1760801-1761082 [Vibrio sp. JC009]
MSRIHFDKDIQPLSEFRAGVTSFIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLSVSN
EDARAQVLGRIKE

Nucleotide

• Length: 282 bp

>AT235715 NZ_LR134334:4493576-4493977 [Pseudomonas chlororaphis]
ATGAAATTCCCGGTCGTGCTGCACAAGGATGCCGACTCCGGATATGGAGTGATCGTCCCCGATGTGCCGGGCTGTTTTTC
CGCCGGTCATACCGCTGCGCAAGCCTTCGAGAATGTGAAAGAAGCCTTGTCGCTGCACTACGAAGGCCTGGTCGCCGATG
GTGAGCCGCTGCCCCAGGTACATGAGGTTGATGTGCATATCGACAATCCCGATTACGCCGGCGGTGTATGGGGGGTGGTC
GATTTCGATATCACGCCTTACTTCGGCAAGGCGGTGCGTTTTAATGCGACGTTGCCGGAGCAACTGTTGGAGCGCATCGA
CCAGACAGTGAAGCGCGACCAGCGCTACCGTTCGCGCTCGGGTTTTCTCGCCGCGGCGGCACTACGCGAGCTCTCCGCCT
AG