Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mosAT/AbiEii-AbiEi |
| Location | 1704782..1706484 | Replicon | chromosome |
| Accession | NZ_CP092107 | ||
| Organism | Vibrio sp. JC009 | ||
Toxin (Protein)
| Gene name | mosT | Uniprot ID | - |
| Locus tag | L3Q72_RS22535 | Protein ID | WP_275132802.1 |
| Coordinates | 1705561..1706484 (+) | Length | 308 a.a. |
Antitoxin (Protein)
| Gene name | mosA | Uniprot ID | - |
| Locus tag | L3Q72_RS22530 | Protein ID | WP_275132801.1 |
| Coordinates | 1704782..1705558 (+) | Length | 259 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| L3Q72_RS22510 (L3Q72_22490) | 1700830..1701669 | + | 840 | WP_275132797.1 | SWIM zinc finger family protein | - |
| L3Q72_RS22515 (L3Q72_22495) | 1701710..1701994 | + | 285 | WP_275132798.1 | hypothetical protein | - |
| L3Q72_RS22520 (L3Q72_22500) | 1702225..1702557 | + | 333 | WP_275132799.1 | helix-turn-helix domain-containing protein | - |
| L3Q72_RS22525 (L3Q72_22505) | 1702550..1703956 | + | 1407 | WP_275132800.1 | HipA domain-containing protein | - |
| L3Q72_RS22530 (L3Q72_22510) | 1704782..1705558 | + | 777 | WP_275132801.1 | type IV toxin-antitoxin system AbiEi family antitoxin | Antitoxin |
| L3Q72_RS22535 (L3Q72_22515) | 1705561..1706484 | + | 924 | WP_275132802.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| L3Q72_RS22540 (L3Q72_22520) | 1706512..1707765 | + | 1254 | WP_275132803.1 | hypothetical protein | - |
| L3Q72_RS22545 (L3Q72_22525) | 1707678..1708193 | + | 516 | WP_275132804.1 | hypothetical protein | - |
| L3Q72_RS22550 (L3Q72_22530) | 1708429..1708779 | - | 351 | WP_275130849.1 | hypothetical protein | - |
| L3Q72_RS22555 (L3Q72_22535) | 1708983..1710479 | + | 1497 | WP_275130850.1 | IS21 family transposase | - |
| L3Q72_RS22560 (L3Q72_22540) | 1710469..1711227 | + | 759 | WP_275130851.1 | IS21-like element helper ATPase IstB | - |
| L3Q72_RS22565 (L3Q72_22545) | 1711227..1711403 | + | 177 | WP_275130852.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 308 a.a. Molecular weight: 35209.26 Da Isoelectric Point: 4.5890
>T235714 WP_275132802.1 NZ_CP092107:1705561-1706484 [Vibrio sp. JC009]
MNKNSIYYQQVKLLIRMLPVVAKEQVFALKGGTAINLFIRDFPRLSVDIDLAYLPLEPREEALENAKAALQRITDNINSQ
PDVKAKFQANKPDELRIVVSNSTATVKIEVSPVARGTLHEPEVLEVAESVEDEFGYAEIPVVSLPDLYGGKICAAMDRQH
PRDLFDVNMLLEAEGISREIFVGFLTYALGHPRPINEVMAPNWQPLETKFHEEFEGMTFRTVELQDLEETRSEMLNALKV
QFTERDRDFLLSFKQGEPDWSLFDVPSIEELPAIRWKLINLNKLKSQNPDKHQELFSKLNQVTEEWL
MNKNSIYYQQVKLLIRMLPVVAKEQVFALKGGTAINLFIRDFPRLSVDIDLAYLPLEPREEALENAKAALQRITDNINSQ
PDVKAKFQANKPDELRIVVSNSTATVKIEVSPVARGTLHEPEVLEVAESVEDEFGYAEIPVVSLPDLYGGKICAAMDRQH
PRDLFDVNMLLEAEGISREIFVGFLTYALGHPRPINEVMAPNWQPLETKFHEEFEGMTFRTVELQDLEETRSEMLNALKV
QFTERDRDFLLSFKQGEPDWSLFDVPSIEELPAIRWKLINLNKLKSQNPDKHQELFSKLNQVTEEWL
Download Length: 924 bp
>T235714 NZ_LR134334:1524644-1524994 [Pseudomonas chlororaphis]
ATGGACGCACTTTTTATTGAGCTGCCCCCGTTCCAACGCCATCGACAGGACTACCTGGACGACGAGCTTTTTCGTAGCTT
GCAGCTTGAATTGCTGAAAGCCCCCGAAGCCGGAGATCTCATCGAGGGAGTCGGTGGCTTGCGCAAGATCCGCTTTGTCG
ATGAGCGACGGCACAAGGGCAAACGCGGCGGGATCCGGGTGATTTATTACTGGTGGTCCGGAGGCGCCCAGTTCTGGCTC
TTCACCCTTTACGCAAAGAACGAGCAGAACGACCTGACATCCCATCAGAAAAAACTGCTCAAGCAACTGCTGAACAGAGA
AGTCGAGGCGAGAACCCATCATGAAACGTGA
ATGGACGCACTTTTTATTGAGCTGCCCCCGTTCCAACGCCATCGACAGGACTACCTGGACGACGAGCTTTTTCGTAGCTT
GCAGCTTGAATTGCTGAAAGCCCCCGAAGCCGGAGATCTCATCGAGGGAGTCGGTGGCTTGCGCAAGATCCGCTTTGTCG
ATGAGCGACGGCACAAGGGCAAACGCGGCGGGATCCGGGTGATTTATTACTGGTGGTCCGGAGGCGCCCAGTTCTGGCTC
TTCACCCTTTACGCAAAGAACGAGCAGAACGACCTGACATCCCATCAGAAAAAACTGCTCAAGCAACTGCTGAACAGAGA
AGTCGAGGCGAGAACCCATCATGAAACGTGA
Antitoxin
Download Length: 259 a.a. Molecular weight: 29716.70 Da Isoelectric Point: 8.6872
>AT235714 WP_275132801.1 NZ_CP092107:1704782-1705558 [Vibrio sp. JC009]
MNNQSKINWLVNHTAPGSLVLQPWLVENGISHSLTQRYAQSGWLYRLMNGVYYRPDMKTNRQPDWADALQALSEQLHFDI
HLSGLTSLTYQGLSHYLVLSSEKVWVGTKEKASLPKWFREFPNQEWLYCRNSRLSEVTEKDFTVLVVDGKELTASSPELA
AYEVVDAIGKHISFEHAAELFQGLVNLSPRKVQSLLNRSKAVQTNRVFLYLGHHHDHQWVKRLDETQIELGSGKRQVVPN
GRYDEKYKITVPESLSIR
MNNQSKINWLVNHTAPGSLVLQPWLVENGISHSLTQRYAQSGWLYRLMNGVYYRPDMKTNRQPDWADALQALSEQLHFDI
HLSGLTSLTYQGLSHYLVLSSEKVWVGTKEKASLPKWFREFPNQEWLYCRNSRLSEVTEKDFTVLVVDGKELTASSPELA
AYEVVDAIGKHISFEHAAELFQGLVNLSPRKVQSLLNRSKAVQTNRVFLYLGHHHDHQWVKRLDETQIELGSGKRQVVPN
GRYDEKYKITVPESLSIR
Download Length: 777 bp
>AT235714 NZ_LR134334:1524984-1525298 [Pseudomonas chlororaphis]
ATGAAACGTGACATCTTTTCCGAACTGGTCGAAGGTTTCGACACCCTGGCCAAAGAGCGCCAAGGCAAGCTCACGCTGCG
CACCCACAAGGTCAAGCTGAACGCACTGCTACCGATCACCGCTGAAGAAGTGCTGGCCGTGCGCGAACAGCTGAACCTGT
CCAGATCGGTATTTGCCATGTACCTGCGCACCAATACTCGGACCCTGGAGAACTGGGAGCAAGGACGGGCAAAACCCAAC
GCCCAGGCCACCACCCTGATCCGCCTGGTACAGCGTTTTCCCGATACGGTGGAGCGGCTGGCAGCCCTTGCCTGA
ATGAAACGTGACATCTTTTCCGAACTGGTCGAAGGTTTCGACACCCTGGCCAAAGAGCGCCAAGGCAAGCTCACGCTGCG
CACCCACAAGGTCAAGCTGAACGCACTGCTACCGATCACCGCTGAAGAAGTGCTGGCCGTGCGCGAACAGCTGAACCTGT
CCAGATCGGTATTTGCCATGTACCTGCGCACCAATACTCGGACCCTGGAGAACTGGGAGCAAGGACGGGCAAAACCCAAC
GCCCAGGCCACCACCCTGATCCGCCTGGTACAGCGTTTTCCCGATACGGTGGAGCGGCTGGCAGCCCTTGCCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|