Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /GNAT-DUF1778
Location 1694129..1694901 Replicon chromosome
Accession NZ_CP092107
Organism Vibrio sp. JC009

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag L3Q72_RS22485 Protein ID WP_275132792.1
Coordinates 1694129..1694632 (-) Length 168 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag L3Q72_RS22490 Protein ID WP_275132793.1
Coordinates 1694629..1694901 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L3Q72_RS22465 (L3Q72_22445) 1690414..1690866 - 453 WP_275132788.1 cytochrome c3 family protein -
L3Q72_RS22470 (L3Q72_22450) 1690892..1692433 - 1542 WP_275132789.1 flavocytochrome c -
L3Q72_RS22475 (L3Q72_22455) 1692778..1693638 - 861 WP_275132790.1 helix-turn-helix transcriptional regulator -
L3Q72_RS22480 (L3Q72_22460) 1693853..1694095 + 243 WP_275132791.1 hypothetical protein -
L3Q72_RS22485 (L3Q72_22465) 1694129..1694632 - 504 WP_275132792.1 GNAT family N-acetyltransferase Toxin
L3Q72_RS22490 (L3Q72_22470) 1694629..1694901 - 273 WP_275132793.1 DUF1778 domain-containing protein Antitoxin
L3Q72_RS22495 (L3Q72_22475) 1695194..1695940 - 747 WP_275132794.1 potassium channel family protein -
L3Q72_RS22500 (L3Q72_22480) 1696230..1697636 + 1407 WP_275132795.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(86-150)

Antitoxin

Vibrio phage ICP1, Orf50

(7-86)


Sequences

Toxin        


Download         Length: 168 a.a.        Molecular weight: 19025.67 Da        Isoelectric Point: 7.9878

>T235713 WP_275132792.1 NZ_CP092107:c1694632-1694129 [Vibrio sp. JC009]
MMNSVLLDKSKHNRNRFNCGIEALNNYLKVMANQQAKKDNTRTFVLEDENDNSYIIGFYTLTMTPINLEALPDKLQKKHQ
SSTSGGLIARLAIDERYKGKGFGEWLLIDALRKLLTASDSVAFPVVIVDAKDGAKQFYERYGFQAFQSAENKLFITISDV
RESLEYQ

Download         Length: 504 bp

>T235713 NZ_LR134333:c5456685-5456344 [Klebsiella oxytoca]
ATGAAAACTCTACCTGCAACAAATCCGCAGGCGGCGACGCTATGTCTGCCACCCGTGGCAGGCTGGCAAATGCTGCTTGC
ACGCCTGCTGGAACAACATTATGGCCTAACACTCAACGACACACCATTCAGTGATGAAAAGGTAATTCAGGAACATATCG
ATGCCGGTATATCTTTGGCCGATGCCGCTAATTTTCTGGTGGAAAAGTACGGGCTGGTTCGTATTGATCGCAGGGGATTC
GACTGGCAAGAACAGTCCCCATATCTGCGGGCAGTCGATATTCTGCGGGCGCGACAGGCAACTGGTTTATTGAAAAGAAA
TCGTATTAGCGCGGCACGGTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9816.46 Da        Isoelectric Point: 10.3418

>AT235713 WP_275132793.1 NZ_CP092107:c1694901-1694629 [Vibrio sp. JC009]
MAATLPRITARVDVDTQDLLTKAAAIAGMSSINSFVLSAAIEKAKEVIEREQALRLSQKDALLLMEALDRPAKPNAKLKA
AAKRYEHKTQ

Download         Length: 273 bp

>AT235713 NZ_LR134333:c5457047-5456706 [Klebsiella oxytoca]
ATGAAATCTACTGACTCAGAGAACGATTCATTTCTAAAATGGGGACTGAATCGTAATGTGACACCTTGCTTTGGCGCTCG
TCTGGTACAGGAGGGAAACCGGCTGCACTATCTGGCTGACCGGGCCAGTATCACTGGTAAGTTCAGCGAAGCAGAATGTT
TTAAGCTGGATGTGGCATTCCCGCATTTTATCAGCCAGATGGAATCGATGCTGACTACTGGTGAAATGAATCCTCGCCAT
GCCCACTGTGTCACCCTGTACCACAATGGTTTCACCTGCGAAGCCGATACCCTTGGCAGTTGCGGCTACGTATACATCGC
CGTTTACTCCACCCATCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References