Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 1393624..1394420 Replicon chromosome
Accession NZ_CP092107
Organism Vibrio sp. JC009

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag L3Q72_RS21175 Protein ID WP_275132542.1
Coordinates 1393890..1394420 (+) Length 177 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag L3Q72_RS21170 Protein ID WP_275132541.1
Coordinates 1393624..1393893 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L3Q72_RS21155 (L3Q72_21140) 1389923..1390798 - 876 WP_275132538.1 radical SAM protein -
L3Q72_RS21160 (L3Q72_21145) 1390969..1391214 - 246 WP_275132539.1 YdcH family protein -
L3Q72_RS21165 (L3Q72_21150) 1391351..1393258 - 1908 WP_275132540.1 methyl-accepting chemotaxis protein -
L3Q72_RS21170 (L3Q72_21155) 1393624..1393893 + 270 WP_275132541.1 DUF1778 domain-containing protein Antitoxin
L3Q72_RS21175 (L3Q72_21160) 1393890..1394420 + 531 WP_275132542.1 GNAT family N-acetyltransferase Toxin
L3Q72_RS21180 (L3Q72_21165) 1394435..1395340 + 906 WP_275132543.1 LysR family transcriptional regulator -
L3Q72_RS21185 (L3Q72_21170) 1395477..1396886 + 1410 WP_275132544.1 dihydrolipoyl dehydrogenase -
L3Q72_RS21190 (L3Q72_21175) 1396940..1398589 - 1650 WP_275132546.1 methyl-accepting chemotaxis protein -
L3Q72_RS21195 (L3Q72_21180) 1398970..1399221 + 252 WP_275132547.1 HPr family phosphocarrier protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(97-153)

Antitoxin

Vibrio phage ICP1, Orf50

(5-81)


Sequences

Toxin        


Download         Length: 177 a.a.        Molecular weight: 20007.30 Da        Isoelectric Point: 9.1189

>T235712 WP_275132542.1 NZ_CP092107:1393890-1394420 [Vibrio sp. JC009]
VSWGKEFVELSKSEHDRSSFDCGEQELNTFIRTQAAKHMQAGISRTMILPGVQPLLNQKYAICAFYSIAPSSISRETLPK
QLSKKLPGYPVPVFLLAQLAVHKEFHGSGLGKISLIRALKYLWEINHHMRAYAIVVDCLTDSAQTFYAKFGFEILCEHNG
RIRMFLPMKTVEQIFN

Download         Length: 531 bp

>T235712 NZ_LR134333:c4917074-4916817 [Klebsiella oxytoca]
ATGAATCTATCCCGTCAGGAACAACGTACCTTACACGTTCTCGCTAAAGGTGGCCGGATCGCGCATATTCGCGATGCATC
AGGCCGCGTAACCTCTGTTGAATGCTACAGCCGCGAAGGGCTCCTGCTCAGCGACTGCACGCTCGCCGTTTTCAAAAAAC
TCAAAACCAAAAAACTCATTAAGTCCGTCAACGGGCAGCCCTACCGTATCAATACCACCGGGCTGAACAACGTTCGCGCT
CAGCTGGACAACCGCTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9880.27 Da        Isoelectric Point: 4.2881

>AT235712 WP_275132541.1 NZ_CP092107:1393624-1393893 [Vibrio sp. JC009]
MATARLDIRLDEEIKIKAEKASALLGLKSLTEYVVRLMDEDATQVIEEHESIVVKDDVFDEFIAACDKAKAPNQALLDAA
KFADESNIK

Download         Length: 270 bp

>AT235712 NZ_LR134333:c4916806-4916255 [Klebsiella oxytoca]
ATGACAAACCATAACTTCACCTTTCACATCACCTCAGAGCGTGATGCTGATGATATTCGCGAAGTTGAAACCCGGGCCTT
CGGCTTTAGCAAAGAGGCCGATCTGGTTGCCGCTTTGCTCAACGATGAAAGTGCTCACCCGAGCTTATCTCTGCTGGCCA
AACATAATGGAAAAGCCGTTGGGCATATTTTGTTCACCCTGGCGACGTTCAAAGGGGAGTCTGACTCTCCGATGATGCAT
ATCCTTGCCCCCCTGGCGGTGGTGCCGGAATACCAGGGCGTGGGCGTAGGCGGATTGCTTATCCAGCGCGGTATTGAGCA
TCTGAAGGCAATGGGGAGCCTGGCGGTATTCGTTCTGGGACATGCCACTTATTACCCGCGGCATGGCTTTGAACCCTGTG
CCGGAGATAAAGGCTATCCGGCGCCTTATCCCATTCCCGAGGAGCATAAAGCCTGCTGGATGCTGCAGCGGCTTTCGTCC
CGGCCGCTGGGGAGAACCGGTCAGATACAGTGCGCCCGGGCGTTAATGAAACCCGAGCACTGGCGCGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References