Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 300839..301404 Replicon chromosome
Accession NZ_CP092107
Organism Vibrio sp. JC009

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag L3Q72_RS16305 Protein ID WP_275132846.1
Coordinates 300839..301126 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L3Q72_RS16310 Protein ID WP_275132845.1
Coordinates 301123..301404 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L3Q72_RS16290 (L3Q72_16280) 296314..297291 - 978 WP_275133219.1 GTP-binding protein -
L3Q72_RS16295 (L3Q72_16285) 297777..299120 + 1344 WP_275133220.1 H(+)/Cl(-) exchange transporter ClcA -
L3Q72_RS16300 (L3Q72_16290) 299495..300517 - 1023 WP_275129409.1 IS110 family transposase -
L3Q72_RS16305 (L3Q72_16295) 300839..301126 - 288 WP_275132846.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L3Q72_RS16310 (L3Q72_16300) 301123..301404 - 282 WP_275132845.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
L3Q72_RS16315 (L3Q72_16305) 302119..302649 - 531 Protein_281 DsbE family thiol:disulfide interchange protein -
L3Q72_RS16320 (L3Q72_16310) 302702..303217 - 516 WP_275133221.1 DUF3299 domain-containing protein -
L3Q72_RS16325 (L3Q72_16315) 303219..303920 - 702 WP_275133222.1 DUF4405 domain-containing protein -
L3Q72_RS16330 (L3Q72_16320) 303921..304550 - 630 WP_275133223.1 flavodoxin -
L3Q72_RS16335 (L3Q72_16325) 304808..305695 + 888 WP_275133224.1 DUF4437 domain-containing protein -
L3Q72_RS16340 (L3Q72_16330) 305769..306314 + 546 WP_275133225.1 disulfide bond formation protein DsbB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-74)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10922.67 Da        Isoelectric Point: 5.6851

>T235711 WP_275132846.1 NZ_CP092107:c301126-300839 [Vibrio sp. JC009]
MKVVWSPLALQKLGDAAEFISLDNPSAARKWVDEVFDKAELLASMPEMGRMVPEMPNTNYREVIFGHYRIIYSISHEIRV
LTVRNCRQILTDDAL

Download         Length: 288 bp

>T235711 NZ_LR134333:4672794-4673012 [Klebsiella oxytoca]
ATGTCTGATAAAACATTAACCAAAATAGACTATTTGATGCGCTTACGACGTTGTCAGACAATTGATACGCTGGAGCGCGT
AATTGAAAAAAATAAATATGAACTTTCTGATAATGAACTGGCGGTATTTTACTCAGCAGCCGATCATCGTCTTGCTGAAC
TGACGATGAATAAACTGTATGACAAGATCCCGCCATCGGTCTGGAAATTCATCCGCTAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10457.97 Da        Isoelectric Point: 5.1881

>AT235711 WP_275132845.1 NZ_CP092107:c301404-301123 [Vibrio sp. JC009]
MSRIHFDKDIQPLSEFRAGVTSFIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLSVSN
EDARAQVLGRIKE

Download         Length: 282 bp

>AT235711 NZ_LR134333:4672393-4672767 [Klebsiella oxytoca]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCGCAGCTTAAATTTCTCTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTTAATGACCCAACCTCTGCTGTCAATCTTCAGCTTAATGAATTGATCGAGC
ACATTGCCGCGTTCGCACTTAATTATAAAATTAAGTATGCTGAGGATAATAAGCTGGTGACTCAGCTTGACGAATATCTG
GATGACACTTTCGTGTTGTTCAGCAACTACGGCATTAACACTGCAGATCTGCAGAAATGGCGTAAATCAGGCAACAGGTT
ATTCCGCTGCTTTGTGAACGCCAGTCGGGAAAACCCGGCCAGTCTTTCTTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References