Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1749393..1749936 Replicon chromosome
Accession NZ_CP092106
Organism Vibrio sp. JC009

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag L3Q72_RS07985 Protein ID WP_275129427.1
Coordinates 1749664..1749936 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L3Q72_RS07980 Protein ID WP_275129426.1
Coordinates 1749393..1749677 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L3Q72_RS07960 (L3Q72_07950) 1744910..1745566 - 657 WP_275129423.1 multiheme c-type cytochrome -
L3Q72_RS07965 (L3Q72_07955) 1746242..1747648 + 1407 WP_275132088.1 ammonia-forming nitrite reductase cytochrome c552 subunit -
L3Q72_RS07970 (L3Q72_07960) 1747869..1748552 + 684 WP_275129424.1 hypothetical protein -
L3Q72_RS07975 (L3Q72_07965) 1748527..1749168 - 642 WP_275129425.1 hypothetical protein -
L3Q72_RS07980 (L3Q72_07970) 1749393..1749677 + 285 WP_275129426.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
L3Q72_RS07985 (L3Q72_07975) 1749664..1749936 + 273 WP_275129427.1 type II toxin-antitoxin system YafQ family toxin Toxin
L3Q72_RS07990 (L3Q72_07980) 1749994..1752609 - 2616 WP_275129428.1 DNA topoisomerase (ATP-hydrolyzing) subunit A -
L3Q72_RS07995 (L3Q72_07985) 1752922..1753635 + 714 WP_275129429.1 bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG -
L3Q72_RS08000 (L3Q72_07990) 1754274..1754636 + 363 WP_275129430.1 endonuclease domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-84)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10460.07 Da        Isoelectric Point: 8.0643

>T235708 WP_275129427.1 NZ_CP092106:1749664-1749936 [Vibrio sp. JC009]
MYALEYSTQFKKDFKKVTKKPISDIMEVGYVVSKLQRGETLEEKFVDHPLTSNWAGFRDCHVKPDLVLIYRIEHSTLQLA
RIGTHSELFG

Download         Length: 273 bp

>T235708 NZ_LR134331:2782666-2782926 [Lacticaseibacillus rhamnosus]
ATGATTAAAACCTGGACCGATGATGCTTGGGCGGACTACATGTATTGGCATGATCAAAACGACAAGCGGACAATCAAACG
AATTAATCAACTCATTCAAGCCATTGACCGTGACCCTTATAAAGGCATCGGAAAACCTGAGCCACTTAGATATGCGCTAA
CCGGAAAATGGTCACGTCGGATTGATCAGGAAAATCGCATCATCTACAGCATTGAAAAGAACCACATTAATATTTTCGCC
TGCCGCACTCACTACAGTTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10192.64 Da        Isoelectric Point: 6.4764

>AT235708 WP_275129426.1 NZ_CP092106:1749393-1749677 [Vibrio sp. JC009]
MKTEMLSTRIDHDTKMAFTQICDDVGLSPSQALKLFAKAVINHGGIPFEIKAPQPNTTTVQAMEELAQGKGHKAESVDAL
ISELTDSKVSHVRS

Download         Length: 285 bp

>AT235708 NZ_LR134331:2782404-2782673 [Lacticaseibacillus rhamnosus]
ATGGAAGCAACGAATTATAGTGATTTCCGCCGCAACCTTAAGCATTATATGAGTCAAGTCAACGAAGACGCCGAACCGCT
ACTGGTTACCGCTAAAGATGATGATGACAATGTGGTGGTTATGAGCAAGCACGATTTTGACGCCATCGAAGAAACCCTGT
ATTTACTCAGCAATCCCAAGCTGATGGCCAAAATCAAACGTGGTGATGCCCAAATTGCCGCTGGAAAGGCTAAACAGCAC
GAGTTGTTAACGGACTTCGATCATGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References