Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1281842..1282337 Replicon chromosome
Accession NZ_CP092106
Organism Vibrio sp. JC009

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag L3Q72_RS05890 Protein ID WP_275131727.1
Coordinates 1281842..1282108 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag L3Q72_RS05895 Protein ID WP_275131728.1
Coordinates 1282095..1282337 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L3Q72_RS05870 (L3Q72_05860) 1277043..1277294 + 252 WP_275131723.1 DUF1289 domain-containing protein -
L3Q72_RS05875 (L3Q72_05865) 1277457..1279124 + 1668 WP_275131724.1 methyl-accepting chemotaxis protein -
L3Q72_RS05880 (L3Q72_05870) 1279581..1280285 + 705 WP_275131725.1 fibrobacter succinogenes major paralogous domain-containing protein -
L3Q72_RS05885 (L3Q72_05875) 1280366..1281292 + 927 WP_275131726.1 SDR family NAD(P)-dependent oxidoreductase -
L3Q72_RS05890 (L3Q72_05880) 1281842..1282108 + 267 WP_275131727.1 BrnT family toxin Toxin
L3Q72_RS05895 (L3Q72_05885) 1282095..1282337 + 243 WP_275131728.1 CopG family transcriptional regulator Antitoxin
L3Q72_RS05900 (L3Q72_05895) 1282726..1284555 - 1830 WP_275131729.1 [Fe-Fe] hydrogenase large subunit C-terminal domain-containing protein -
L3Q72_RS05905 (L3Q72_05900) 1284783..1285745 + 963 WP_275131730.1 ABC transporter substrate-binding protein -
L3Q72_RS05910 (L3Q72_05905) 1285735..1286469 + 735 WP_275131731.1 ABC transporter permease subunit -
L3Q72_RS05915 (L3Q72_05910) 1286456..1287178 + 723 WP_275131732.1 ATP-binding cassette domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10174.44 Da        Isoelectric Point: 6.4647

>T235706 WP_275131727.1 NZ_CP092106:1281842-1282108 [Vibrio sp. JC009]
MITFEFDENKSRTNLEKHGIDFYTAQGLWNDSDLIEIPANTSDEPRYLVIGLLNGKHWSGVITYRGTNIRIISVRRSRKV
EVNLYESA

Download         Length: 267 bp

>T235706 NZ_LR134331:c2500395-2500048 [Lacticaseibacillus rhamnosus]
ATGACATATAAGGCTAAGCAAGGTGATGTGGTGTGGCTTGATTTTGATCCGTCCGAGGGTCATGAAATTAGAAAAAGATG
CCCAGCTGTTGTTTTAAGCAGTAACGCATACAATCGTGCAACCGGATTTGTGATTGTCGCACCAATTACCTCAACAATTC
GGACACTACCTGGTTATGTTGATATTGTATCCAATAAAATTCGTGGTCAGGTTGTCACTTCGCAGGTTTATTCTCTGGAT
GTCACTGAACAAGGCAACCGAAAAATCGATTTTATTGAAAGAATGAACATTGAAGATTTTTATACAGTCGCTCAATTCAC
CAAAATGAATTTTGATTTTAAATTTTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9272.55 Da        Isoelectric Point: 6.8808

>AT235706 WP_275131728.1 NZ_CP092106:1282095-1282337 [Vibrio sp. JC009]
MKAHEFDAKFESDEDILGDLDLSKAKRPMQKQKRVNVDFPAWMLESLDREASRVGVTRQSIIKIWLAERLESVAHHHTAN

Download         Length: 243 bp

>AT235706 NZ_LR134331:c2500610-2500395 [Lacticaseibacillus rhamnosus]
ATGGATGTGAAAGTTGTAAAACGTGGAAACTCGTTAGCTTTATCACTTCCGAGCAGTGCGGGTTTCAAACGAGGCGAGGC
GTTTTTGCTGATTTCAGATGAAAAAGGTGGTTATCTGTTGATCCCAAAGGTAAAAAATCCCTATACCAAAGCAAAACCAT
TATCATTCCATCAAGAAGAAGCTTGGCCGGATTTTGACTATGAGGATATTGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References