Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relE-yefM/YoeB-YefM |
| Location | 1183325..1183833 | Replicon | chromosome |
| Accession | NZ_CP092106 | ||
| Organism | Vibrio sp. JC009 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | L3Q72_RS05540 | Protein ID | WP_275131658.1 |
| Coordinates | 1183325..1183585 (-) | Length | 87 a.a. |
Antitoxin (Protein)
| Gene name | yefM | Uniprot ID | - |
| Locus tag | L3Q72_RS05545 | Protein ID | WP_275131659.1 |
| Coordinates | 1183582..1183833 (-) | Length | 84 a.a. |
Genomic Context
Location: 1179396..1179677 (282 bp)
Type: Others
Protein ID: WP_275131653.1
Type: Others
Protein ID: WP_275131653.1
Location: 1179894..1180469 (576 bp)
Type: Others
Protein ID: WP_275131654.1
Type: Others
Protein ID: WP_275131654.1
Location: 1180647..1180727 (81 bp)
Type: Others
Protein ID: Protein_1049
Type: Others
Protein ID: Protein_1049
Location: 1182895..1183275 (381 bp)
Type: Others
Protein ID: WP_275131657.1
Type: Others
Protein ID: WP_275131657.1
Location: 1188478..1188609 (132 bp)
Type: Others
Protein ID: WP_275131662.1
Type: Others
Protein ID: WP_275131662.1
Location: 1178905..1179219 (315 bp)
Type: Others
Protein ID: WP_275131652.1
Type: Others
Protein ID: WP_275131652.1
Location: 1180842..1181093 (252 bp)
Type: Others
Protein ID: WP_275131655.1
Type: Others
Protein ID: WP_275131655.1
Location: 1181250..1182578 (1329 bp)
Type: Others
Protein ID: WP_275131656.1
Type: Others
Protein ID: WP_275131656.1
Location: 1183325..1183585 (261 bp)
Type: Toxin
Protein ID: WP_275131658.1
Type: Toxin
Protein ID: WP_275131658.1
Location: 1183582..1183833 (252 bp)
Type: Antitoxin
Protein ID: WP_275131659.1
Type: Antitoxin
Protein ID: WP_275131659.1
Location: 1184027..1186342 (2316 bp)
Type: Others
Protein ID: WP_275131660.1
Type: Others
Protein ID: WP_275131660.1
Location: 1186566..1188479 (1914 bp)
Type: Others
Protein ID: WP_275131661.1
Type: Others
Protein ID: WP_275131661.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| L3Q72_RS05505 (L3Q72_05500) | 1178905..1179219 | - | 315 | WP_275131652.1 | cupin domain-containing protein | - |
| L3Q72_RS05510 (L3Q72_05505) | 1179396..1179677 | + | 282 | WP_275131653.1 | helix-turn-helix transcriptional regulator | - |
| L3Q72_RS05515 (L3Q72_05510) | 1179894..1180469 | + | 576 | WP_275131654.1 | outer membrane beta-barrel protein | - |
| L3Q72_RS05520 (L3Q72_05515) | 1180647..1180727 | + | 81 | Protein_1049 | CopG family transcriptional regulator | - |
| L3Q72_RS05525 (L3Q72_05520) | 1180842..1181093 | - | 252 | WP_275131655.1 | DUF2999 family protein | - |
| L3Q72_RS05530 (L3Q72_05525) | 1181250..1182578 | - | 1329 | WP_275131656.1 | guanine deaminase | - |
| L3Q72_RS05535 (L3Q72_05530) | 1182895..1183275 | + | 381 | WP_275131657.1 | CoA-binding protein | - |
| L3Q72_RS05540 (L3Q72_05535) | 1183325..1183585 | - | 261 | WP_275131658.1 | Txe/YoeB family addiction module toxin | Toxin |
| L3Q72_RS05545 (L3Q72_05540) | 1183582..1183833 | - | 252 | WP_275131659.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
| L3Q72_RS05550 (L3Q72_05545) | 1184027..1186342 | - | 2316 | WP_275131660.1 | methyl-accepting chemotaxis protein | - |
| L3Q72_RS05555 (L3Q72_05550) | 1186566..1188479 | - | 1914 | WP_275131661.1 | TRAP transporter permease | - |
| L3Q72_RS05560 | 1188478..1188609 | + | 132 | WP_275131662.1 | hypothetical protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 87 a.a. Molecular weight: 10548.22 Da Isoelectric Point: 9.9315
>T235705 WP_275131658.1 NZ_CP092106:c1183585-1183325 [Vibrio sp. JC009]
MKLTFSAHAWEDYLYWQKTDKKILKRINTLIKDIRREPYEGLGKPEPLKHGLSGYWSRRINDEHRIIYKCKENNILIAQL
RYHYEL
MKLTFSAHAWEDYLYWQKTDKKILKRINTLIKDIRREPYEGLGKPEPLKHGLSGYWSRRINDEHRIIYKCKENNILIAQL
RYHYEL
Download Length: 261 bp
>T235705 NZ_LR134331:c522867-522682 [Lacticaseibacillus rhamnosus]
TTGCAGCGTCAAGGTCATGTAAAATTAGCTTCTCTACATGACCATGCTTTAAAGGGTGCTCACAGCGGCGAACGAGCATT
GCGTGTTGCTCCTGATTGGCTTCTCGTTTATAAAGTCGATGCTGAAGCGTTAATTTTAATGCTTCTTGCAACAGGCACAC
ACCGCGATACATTGAACATTGAGTAA
TTGCAGCGTCAAGGTCATGTAAAATTAGCTTCTCTACATGACCATGCTTTAAAGGGTGCTCACAGCGGCGAACGAGCATT
GCGTGTTGCTCCTGATTGGCTTCTCGTTTATAAAGTCGATGCTGAAGCGTTAATTTTAATGCTTCTTGCAACAGGCACAC
ACCGCGATACATTGAACATTGAGTAA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9167.43 Da Isoelectric Point: 4.4621
>AT235705 WP_275131659.1 NZ_CP092106:c1183833-1183582 [Vibrio sp. JC009]
MDAISYTAARANLASTMKKVCNDHAPVIITRKSEAPVVMISLEDFEAMQETTYLLRAPANARRLLESVAELESGNGEERD
LIE
MDAISYTAARANLASTMKKVCNDHAPVIITRKSEAPVVMISLEDFEAMQETTYLLRAPANARRLLESVAELESGNGEERD
LIE
Download Length: 252 bp
>AT235705 NZ_LR134331:c523167-522895 [Lacticaseibacillus rhamnosus]
ATGACCAAAAAATCCCGCATCAGCGTTAGGATTGATACCAAAACTAAAGAACGAGCGCTCCATGTTCTTAATAGCATGGG
ATTAGATATTTCCTCGGCTATTAACATGTACCTGAAACGGATTGGTGACACCGGTGCATTGCCATTTACACCTCCAATGT
CATTTGTTGATCAGCTTCAAGTTGCAGAAGCTGATGTTAAAGCGGGGCGAATAAAAAGCTTCAAGACTGTCGATGCTTTG
ATGAAGGATTTATACAGTGATGTTGACGATTAA
ATGACCAAAAAATCCCGCATCAGCGTTAGGATTGATACCAAAACTAAAGAACGAGCGCTCCATGTTCTTAATAGCATGGG
ATTAGATATTTCCTCGGCTATTAACATGTACCTGAAACGGATTGGTGACACCGGTGCATTGCCATTTACACCTCCAATGT
CATTTGTTGATCAGCTTCAAGTTGCAGAAGCTGATGTTAAAGCGGGGCGAATAAAAAGCTTCAAGACTGTCGATGCTTTG
ATGAAGGATTTATACAGTGATGTTGACGATTAA