Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DhiAT/-
Location 254156..254934 Replicon chromosome
Accession NZ_CP092106
Organism Vibrio sp. JC009

Toxin (Protein)


Gene name dhiT Uniprot ID -
Locus tag L3Q72_RS01200 Protein ID WP_275130885.1
Coordinates 254156..254419 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name dhiA Uniprot ID -
Locus tag L3Q72_RS01205 Protein ID WP_275130886.1
Coordinates 254419..254934 (+) Length 172 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L3Q72_RS01180 (L3Q72_01180) 249157..251031 + 1875 WP_275130882.1 argininosuccinate lyase -
L3Q72_RS01185 (L3Q72_01185) 251343..251597 - 255 WP_275130883.1 DUF3624 domain-containing protein -
L3Q72_RS01190 (L3Q72_01190) 251888..252178 + 291 WP_031493033.1 co-chaperone GroES -
L3Q72_RS01195 (L3Q72_01195) 252225..253871 + 1647 WP_275130884.1 chaperonin GroEL -
L3Q72_RS01200 (L3Q72_01200) 254156..254419 + 264 WP_275130885.1 DUF4160 domain-containing protein Toxin
L3Q72_RS01205 (L3Q72_01205) 254419..254934 + 516 WP_275130886.1 transcriptional regulator Antitoxin
L3Q72_RS01210 (L3Q72_01210) 255232..255915 - 684 WP_275130887.1 DNA-3-methyladenine glycosylase I -
L3Q72_RS01215 (L3Q72_01215) 256267..256899 - 633 WP_004410522.1 cAMP-activated global transcriptional regulator CRP -
L3Q72_RS01220 (L3Q72_01220) 257144..258013 - 870 WP_275130888.1 phosphoribulokinase -
L3Q72_RS01225 (L3Q72_01225) 258045..258257 - 213 WP_275130889.1 YheU family protein -
L3Q72_RS01230 (L3Q72_01230) 258273..259244 - 972 WP_275130890.1 hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF4160

(10-74)

Antitoxin

Uncharacterized protein HI1420

(82-159)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10090.65 Da        Isoelectric Point: 6.4825

>T235703 WP_275130885.1 NZ_CP092106:254156-254419 [Vibrio sp. JC009]
MPEILKRLLGLKFQMRYEDNDFHNRPHIHVSFGEYEASIAIDDIEVLAGFLPPKKRKLAEFYIDKHRDELLLAWDGAVIG
QGIGRIN

Download         Length: 264 bp

>T235703 NZ_LR134330:5537840-5538418 [Pseudomonas aeruginosa]
ATGTCCCTCGAACTGCTGAGCAACCGCCTCGAATTCCTCCGCGAAGCCGAACGCCTGAAAGACGTCCTGCGCTCCGCGCA
CACCTCCTCCGGCCGCCCGGAAAGCACCGCCGAACATAGCTGGCGGCTTTGCCTGATGGCACTGGCCTTCGAGGACCAAC
TGGCCGGCCTGGACCTCGGCAAGGTTCTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCC
GCCGTCGAGCAAGCGGCGCACCCGGACAAGGGCGAACAGGAACGCGCCGACCTGTTGCAGCTGACCCGTCATCTGGACAC
ACCGCTGCGCGATCGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGTCCGCCGAAGCCCTGGCAGTGAAAGCGC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGCCGTCGCTATACCGACCGCGCACCGCTGTTCAAGACCCTGCGCGAGTTACTCGACGCCAGGACCCGACAGCGCCTCGC
AGCTCGGCGCGACGCCTAG

Antitoxin


Download         Length: 172 a.a.        Molecular weight: 19284.81 Da        Isoelectric Point: 4.6424

>AT235703 WP_275130886.1 NZ_CP092106:254419-254934 [Vibrio sp. JC009]
MLKIVDLDWLSGYLLELEFSDGFKGIVDLEEVFNSEPYKQIQDFSAFSLEGTYLDWDGVELSANILRKMAAGKGHYTDRP
CVSASNMEDVLKQAAWDAIVSNRPDIFQAAIKGFVEEYGIQKIQQHTNLKSRPSIYKALSSNKSPKLDTLIQLGHAAFEL
EFESREISQKG

Download         Length: 516 bp

>AT235703 NZ_LR134330:5537198-5537752 [Pseudomonas aeruginosa]
ATGACCGAGCCTCTCCCTTCTTCGTCCCTGGGCCCCGCCCTGCGTCGCTGGCGCCTGCTGCACCGGGTCAAGCAAACGCA
TGCCGCCGAATTGCTCGGCGTGGCGCAATCGACCATCTCGCGCTGGGAGTCCGGTACCCAGGCGCTGCTGGTGGAGGAAC
GGGCACGCCTGGAGCGTCTGCTCGGCGCCCGCCTGGAAAGCGCCGCCGACCAGGCACTGGCCCGCCTGGTCGAGGCCAAC
CCGCAACCCGTGCACCTGATCTGCGACCTCACCCATCGCTTGCTGGCCTGTTCGCCGGCACGCGCCGCGCAATTCGGCGT
GCCCCTCGGCGAACTGCTCGACCGTTCGCTGTGGCCCTATTGCAGCGAGGAAATCCTCCGCCAGGAAGCCACCCTCGAGG
AACTCGGCTGGCGCGAACTGCTGGCACCGCCGGCGCTGGAGTTCGCCAGCGGAGCGAACGCCTCGGCCATCGTGCCGATC
CGGCGCAGCCGTTGCCGCTGGACCCGCATGACCCTCTCGGACGGACGCGCGGTGCGCCTGGTGGAAACCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References