Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | DhiAT/- |
| Location | 254156..254934 | Replicon | chromosome |
| Accession | NZ_CP092106 | ||
| Organism | Vibrio sp. JC009 | ||
Toxin (Protein)
| Gene name | dhiT | Uniprot ID | - |
| Locus tag | L3Q72_RS01200 | Protein ID | WP_275130885.1 |
| Coordinates | 254156..254419 (+) | Length | 88 a.a. |
Antitoxin (Protein)
| Gene name | dhiA | Uniprot ID | - |
| Locus tag | L3Q72_RS01205 | Protein ID | WP_275130886.1 |
| Coordinates | 254419..254934 (+) | Length | 172 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| L3Q72_RS01180 (L3Q72_01180) | 249157..251031 | + | 1875 | WP_275130882.1 | argininosuccinate lyase | - |
| L3Q72_RS01185 (L3Q72_01185) | 251343..251597 | - | 255 | WP_275130883.1 | DUF3624 domain-containing protein | - |
| L3Q72_RS01190 (L3Q72_01190) | 251888..252178 | + | 291 | WP_031493033.1 | co-chaperone GroES | - |
| L3Q72_RS01195 (L3Q72_01195) | 252225..253871 | + | 1647 | WP_275130884.1 | chaperonin GroEL | - |
| L3Q72_RS01200 (L3Q72_01200) | 254156..254419 | + | 264 | WP_275130885.1 | DUF4160 domain-containing protein | Toxin |
| L3Q72_RS01205 (L3Q72_01205) | 254419..254934 | + | 516 | WP_275130886.1 | transcriptional regulator | Antitoxin |
| L3Q72_RS01210 (L3Q72_01210) | 255232..255915 | - | 684 | WP_275130887.1 | DNA-3-methyladenine glycosylase I | - |
| L3Q72_RS01215 (L3Q72_01215) | 256267..256899 | - | 633 | WP_004410522.1 | cAMP-activated global transcriptional regulator CRP | - |
| L3Q72_RS01220 (L3Q72_01220) | 257144..258013 | - | 870 | WP_275130888.1 | phosphoribulokinase | - |
| L3Q72_RS01225 (L3Q72_01225) | 258045..258257 | - | 213 | WP_275130889.1 | YheU family protein | - |
| L3Q72_RS01230 (L3Q72_01230) | 258273..259244 | - | 972 | WP_275130890.1 | hydrolase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 88 a.a. Molecular weight: 10090.65 Da Isoelectric Point: 6.4825
>T235703 WP_275130885.1 NZ_CP092106:254156-254419 [Vibrio sp. JC009]
MPEILKRLLGLKFQMRYEDNDFHNRPHIHVSFGEYEASIAIDDIEVLAGFLPPKKRKLAEFYIDKHRDELLLAWDGAVIG
QGIGRIN
MPEILKRLLGLKFQMRYEDNDFHNRPHIHVSFGEYEASIAIDDIEVLAGFLPPKKRKLAEFYIDKHRDELLLAWDGAVIG
QGIGRIN
Download Length: 264 bp
>T235703 NZ_LR134330:5537840-5538418 [Pseudomonas aeruginosa]
ATGTCCCTCGAACTGCTGAGCAACCGCCTCGAATTCCTCCGCGAAGCCGAACGCCTGAAAGACGTCCTGCGCTCCGCGCA
CACCTCCTCCGGCCGCCCGGAAAGCACCGCCGAACATAGCTGGCGGCTTTGCCTGATGGCACTGGCCTTCGAGGACCAAC
TGGCCGGCCTGGACCTCGGCAAGGTTCTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCC
GCCGTCGAGCAAGCGGCGCACCCGGACAAGGGCGAACAGGAACGCGCCGACCTGTTGCAGCTGACCCGTCATCTGGACAC
ACCGCTGCGCGATCGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGTCCGCCGAAGCCCTGGCAGTGAAAGCGC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGCCGTCGCTATACCGACCGCGCACCGCTGTTCAAGACCCTGCGCGAGTTACTCGACGCCAGGACCCGACAGCGCCTCGC
AGCTCGGCGCGACGCCTAG
ATGTCCCTCGAACTGCTGAGCAACCGCCTCGAATTCCTCCGCGAAGCCGAACGCCTGAAAGACGTCCTGCGCTCCGCGCA
CACCTCCTCCGGCCGCCCGGAAAGCACCGCCGAACATAGCTGGCGGCTTTGCCTGATGGCACTGGCCTTCGAGGACCAAC
TGGCCGGCCTGGACCTCGGCAAGGTTCTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCC
GCCGTCGAGCAAGCGGCGCACCCGGACAAGGGCGAACAGGAACGCGCCGACCTGTTGCAGCTGACCCGTCATCTGGACAC
ACCGCTGCGCGATCGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGTCCGCCGAAGCCCTGGCAGTGAAAGCGC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGCCGTCGCTATACCGACCGCGCACCGCTGTTCAAGACCCTGCGCGAGTTACTCGACGCCAGGACCCGACAGCGCCTCGC
AGCTCGGCGCGACGCCTAG
Antitoxin
Download Length: 172 a.a. Molecular weight: 19284.81 Da Isoelectric Point: 4.6424
>AT235703 WP_275130886.1 NZ_CP092106:254419-254934 [Vibrio sp. JC009]
MLKIVDLDWLSGYLLELEFSDGFKGIVDLEEVFNSEPYKQIQDFSAFSLEGTYLDWDGVELSANILRKMAAGKGHYTDRP
CVSASNMEDVLKQAAWDAIVSNRPDIFQAAIKGFVEEYGIQKIQQHTNLKSRPSIYKALSSNKSPKLDTLIQLGHAAFEL
EFESREISQKG
MLKIVDLDWLSGYLLELEFSDGFKGIVDLEEVFNSEPYKQIQDFSAFSLEGTYLDWDGVELSANILRKMAAGKGHYTDRP
CVSASNMEDVLKQAAWDAIVSNRPDIFQAAIKGFVEEYGIQKIQQHTNLKSRPSIYKALSSNKSPKLDTLIQLGHAAFEL
EFESREISQKG
Download Length: 516 bp
>AT235703 NZ_LR134330:5537198-5537752 [Pseudomonas aeruginosa]
ATGACCGAGCCTCTCCCTTCTTCGTCCCTGGGCCCCGCCCTGCGTCGCTGGCGCCTGCTGCACCGGGTCAAGCAAACGCA
TGCCGCCGAATTGCTCGGCGTGGCGCAATCGACCATCTCGCGCTGGGAGTCCGGTACCCAGGCGCTGCTGGTGGAGGAAC
GGGCACGCCTGGAGCGTCTGCTCGGCGCCCGCCTGGAAAGCGCCGCCGACCAGGCACTGGCCCGCCTGGTCGAGGCCAAC
CCGCAACCCGTGCACCTGATCTGCGACCTCACCCATCGCTTGCTGGCCTGTTCGCCGGCACGCGCCGCGCAATTCGGCGT
GCCCCTCGGCGAACTGCTCGACCGTTCGCTGTGGCCCTATTGCAGCGAGGAAATCCTCCGCCAGGAAGCCACCCTCGAGG
AACTCGGCTGGCGCGAACTGCTGGCACCGCCGGCGCTGGAGTTCGCCAGCGGAGCGAACGCCTCGGCCATCGTGCCGATC
CGGCGCAGCCGTTGCCGCTGGACCCGCATGACCCTCTCGGACGGACGCGCGGTGCGCCTGGTGGAAACCCTCTGA
ATGACCGAGCCTCTCCCTTCTTCGTCCCTGGGCCCCGCCCTGCGTCGCTGGCGCCTGCTGCACCGGGTCAAGCAAACGCA
TGCCGCCGAATTGCTCGGCGTGGCGCAATCGACCATCTCGCGCTGGGAGTCCGGTACCCAGGCGCTGCTGGTGGAGGAAC
GGGCACGCCTGGAGCGTCTGCTCGGCGCCCGCCTGGAAAGCGCCGCCGACCAGGCACTGGCCCGCCTGGTCGAGGCCAAC
CCGCAACCCGTGCACCTGATCTGCGACCTCACCCATCGCTTGCTGGCCTGTTCGCCGGCACGCGCCGCGCAATTCGGCGT
GCCCCTCGGCGAACTGCTCGACCGTTCGCTGTGGCCCTATTGCAGCGAGGAAATCCTCCGCCAGGAAGCCACCCTCGAGG
AACTCGGCTGGCGCGAACTGCTGGCACCGCCGGCGCTGGAGTTCGCCAGCGGAGCGAACGCCTCGGCCATCGTGCCGATC
CGGCGCAGCCGTTGCCGCTGGACCCGCATGACCCTCTCGGACGGACGCGCGGTGCGCCTGGTGGAAACCCTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|