Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 232806..233325 Replicon chromosome
Accession NZ_CP092106
Organism Vibrio sp. JC009

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag L3Q72_RS01115 Protein ID WP_275130870.1
Coordinates 233041..233325 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag L3Q72_RS01110 Protein ID WP_275130869.1
Coordinates 232806..233048 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L3Q72_RS01095 (L3Q72_01095) 228468..228788 - 321 WP_275130866.1 met regulon transcriptional regulator MetJ -
L3Q72_RS01100 (L3Q72_01100) 229080..230246 + 1167 WP_275130867.1 O-succinylhomoserine (thiol)-lyase -
L3Q72_RS01105 (L3Q72_01105) 230247..232652 + 2406 WP_275130868.1 bifunctional aspartate kinase/homoserine dehydrogenase II -
L3Q72_RS01110 (L3Q72_01110) 232806..233048 + 243 WP_275130869.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
L3Q72_RS01115 (L3Q72_01115) 233041..233325 + 285 WP_275130870.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L3Q72_RS01120 (L3Q72_01120) 233501..234388 + 888 WP_275130871.1 methylenetetrahydrofolate reductase -
L3Q72_RS01125 (L3Q72_01125) 234443..234982 - 540 WP_275130872.1 PadR family transcriptional regulator -
L3Q72_RS01130 (L3Q72_01130) 235425..238058 - 2634 WP_275130873.1 phosphoenolpyruvate carboxylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - wbtL / manB / ugd 173637..233325 59688


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-88)

Antitoxin

Antitoxin ParD

(1-71)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11343.07 Da        Isoelectric Point: 7.3199

>T235702 WP_275130870.1 NZ_CP092106:233041-233325 [Vibrio sp. JC009]
MYKLSLRAVKDIESIYEYTLLNFGECRADKYTNDLESCLEILAESPFIGRESNEIRKGIRRHDFQKHSIFYRVRELDVFI
IRILHQQMYPALHF

Download         Length: 285 bp

>T235702 NZ_LR134330:3709019-3709606 [Pseudomonas aeruginosa]
ATGTCGAGGAGGGCGCCCATGTTCAAGCCGCTACCGATCACCCTGCAGCGCGGAGCCTTGCGTCTCGAGCCGCTGGTGGA
AGCGGACATTCCCGAGCTGGTGAGCCTCGCCGAAGCCAACCGCGAGGCGCTGCAGTACATGGACGGACCGACGCGGCCGG
ACTGGTACCGCCAGAGCCTCGCCGAGCAGCGCGAGGGCAGGGCGTTGCCGCTCGCCGTCCGCCTCGGCGTGCAACTGGTC
GGGACCACGCGCTTCGCCGAATTCCTTCCCGCCTTGCCGGCCTGCGAGATCGGCTGGACCTGGCTCGACCAGGCCCAGCA
CGGCAGCGGCCTGAACCGCATGATCAAGTACCTGATGCTCAAGCATGCCTTCGACAACCTGCGCATGGTCCGCGTGCAGC
TCAGCACGGCGGCGAGCAACCTGCGCGCCCAGGGCGCCATCGACAAGCTCGGCGCGCAGCGCGAGGGCGTGCTGCGCAAC
CACCGGCGGCTGGCCGGCGGGCGGCTAGACGACACCTTCGTCTACAGCATCACCGACCACGAATGGCCGCAGGTCAAGGC
GGCGCTGGAAGCCAGCTTCACCGGCTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8917.16 Da        Isoelectric Point: 6.4696

>AT235702 WP_275130869.1 NZ_CP092106:232806-233048 [Vibrio sp. JC009]
MARTTSVTIGEPLEKFVNRMLESGRYGSASEVMRSALRLLEQQENQLEHLRNAIDEGELSGESTLSVKEIVAKKKASMHV

Download         Length: 243 bp

>AT235702 NZ_LR134330:3709669-3710523 [Pseudomonas aeruginosa]
GTGCCGGACGAGACGAGCGGAGAACACACGCATTTCTGGCGCGCCGCCGAACTGGGCGGCGTCGAACTGCTGCACGCGCG
CTATGTGGAGCAGCGCTTCGCGCCGCACGTGCACAGCAGCTTCGCCCTGGTCATCATCGAGCAGGGCGCGCAGCGCTTCC
GCCATCGTGGCGGCGAGCACCTGGCCCCGCTGGGCAGCATGGTGCTGATCAACCCCGACGAAGTGCACACCGGCTCCAAG
GCCCATGATGCCGGTTGGCTCTATCGCGGCTACTACCCGGAGATGGAGCAGATCGACGGGATTCTCGACGAGCTGGAAAT
CCATCATGGCGGCGTGCCGCGTTTCGCCGACAGCGTGATCCACGACCAGCCCCTGGCACGCGCCTTCGTCCACTTGCACC
GCCTGCTGGCCGAGCATGCCGGCAGCCTGGAAACCCAGACCCGCTGGCGCGAGACGGTGCTCGCCCTGTTCCGTCGCCAC
GCCCGCCTGCCAGAAGCGCCGAAGGCCGGGCAGGAGCCGTTGGCGGTGGCCCGCGCCCGCGAACTGCTGGCGGCGCGGTT
GCTCGATCCGCCTTCGCTGGAGGAACTGGCGGCGGCGGTCAATCTGTCCCCGTTCCATTTTGCCCGGGTCTTCCGTCGCG
CCACCGGCATGCCGCCCCACGCCTGGCTCAGACAGCGCCGCCTGGAGCAGGCCAGGGCACTGCTCAAGAGCGGCCGGGCG
CCGCTGGAGGTGGCCCTGGAGCTGGGCTTCGCCGACCAGAGCCACCTCGGTCGCCAGTTCAAGCAGGCCTACGGGGTGGC
ACCGGGTGAATACCGCTCGGCCTGCGCGCGCTCGTCCTTGACGACATACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References