Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1114862..1115493 Replicon chromosome
Accession NZ_CP092104
Organism Flagellatimonas centrodinii strain R2A-3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JN531_RS05320 Protein ID WP_228347822.1
Coordinates 1114862..1115263 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JN531_RS05325 Protein ID WP_228347823.1
Coordinates 1115263..1115493 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JN531_RS05295 (JN531_005295) 1110779..1111858 - 1080 WP_228347817.1 alkene reductase -
JN531_RS05300 (JN531_005300) 1111921..1112406 - 486 WP_228347818.1 hypothetical protein -
JN531_RS05305 (JN531_005305) 1112396..1112794 - 399 WP_228347819.1 hypothetical protein -
JN531_RS05310 (JN531_005310) 1112944..1113819 - 876 WP_228347820.1 hypothetical protein -
JN531_RS05315 (JN531_005315) 1113947..1114813 + 867 WP_228347821.1 TauD/TfdA family dioxygenase -
JN531_RS05320 (JN531_005320) 1114862..1115263 - 402 WP_228347822.1 tRNA(fMet)-specific endonuclease VapC Toxin
JN531_RS05325 (JN531_005325) 1115263..1115493 - 231 WP_228347823.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
JN531_RS05330 (JN531_005330) 1115789..1116028 + 240 WP_228347824.1 hypothetical protein -
JN531_RS05335 (JN531_005335) 1116256..1116600 + 345 WP_239795350.1 type II toxin-antitoxin system ParD family antitoxin -
JN531_RS05340 (JN531_005340) 1116587..1116880 + 294 WP_228347826.1 type II toxin-antitoxin system RelE/ParE family toxin -
JN531_RS05345 (JN531_005345) 1117120..1117719 - 600 WP_228347827.1 porin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14725.84 Da        Isoelectric Point: 7.4735

>T235699 WP_228347822.1 NZ_CP092104:c1115263-1114862 [Flagellatimonas centrodinii]
MLRYLLDTNLCIETIRHRPAGLRAAFNRHHGHMGISAVTVMELLYGVELSAQTQRNLADVEGFIARLDVLDYDAAAAAHT
AQIRAELKVAGTQIGPYDQMIAGHARSRGLVVVTNNTKEFQRVAGLRIEDWTT

Download         Length: 402 bp

>T235699 NZ_LR134330:c718018-717740 [Pseudomonas aeruginosa]
ATGATTCTGACCTTTCGCTGCGACGAGACTCGTCAGCTTTTTGAGACGGGTCTTTCGAGGCGGTGGGGAGCGATCCTCAC
AGTCGCTACGCGTAAGCTCGCAATGCATCATGCGGCTACGGAGCTTCGAGACTTGCGCTCTCCACCTGGAAACCGGTTGG
AGCCGTTGCAGGGAAAGCGGGTGGGCCAACATAGCATCAGGATCAATGACCAGTGGCGTGTCTGTTTCGTCTGGACGGAT
GCGGGTCCCGAAGAAGTCGAAATAGTTGATTACCACTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8308.25 Da        Isoelectric Point: 4.7247

>AT235699 WP_228347823.1 NZ_CP092104:c1115493-1115263 [Flagellatimonas centrodinii]
MEQGAVFKSNRSQAIRLSKAAALPDDVKRVDVVSIGRTRIITPAGEAWDSWFEGAGVSADYLAEREQPAAQERDAF

Download         Length: 231 bp

>AT235699 NZ_LR134330:c717728-717423 [Pseudomonas aeruginosa]
ATGGCTACCAATGGTATGCGCCCCATCCATCCTGGGGAAATATTACGCGATGAGTTTCTGATGGAGTTGGATATCTCTCC
AGCTGCCCTAGCACGCGCTTTGAAAGTCTCCGCTCCGACAGTGAACGATATCGTTCGTGAGCAGCGTGGTATCTCCGCAG
ATATGGCGATTCGTCTGGGGCGTTACTTTGATACGTCCGCTCAGTTCTGGATGAATCTCCAGAGTGAGTACTCGTTAGCA
ACTGCTTATGCGGCGAATGGCGAGCAGATCGAACATGAGATTGAGCCGCTGCTTGCTCACGGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References