Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1886418..1886563 Replicon chromosome
Accession NZ_CP092077
Organism Klebsiella pneumoniae strain P1-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1886454..1886556 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1886418..1886563 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MDE60_RS09030 (MDE60_09020) 1881548..1883608 + 2061 WP_004148850.1 oligopeptidase B -
MDE60_RS09035 (MDE60_09025) 1883612..1884271 - 660 WP_032435029.1 exodeoxyribonuclease X -
MDE60_RS09040 (MDE60_09030) 1884350..1884580 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MDE60_RS09045 (MDE60_09035) 1884693..1885067 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MDE60_RS09050 (MDE60_09040) 1885071..1885940 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
MDE60_RS09055 (MDE60_09045) 1885957..1886295 + 339 WP_180812522.1 YebY family protein -
- 1886418..1886563 - 146 - - Antitoxin
- 1886454..1886556 + 103 - - Toxin
MDE60_RS09060 (MDE60_09050) 1886931..1887074 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MDE60_RS09065 (MDE60_09055) 1887179..1888147 - 969 WP_004151446.1 VirK/YbjX family protein -
MDE60_RS09070 (MDE60_09060) 1888304..1888957 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
MDE60_RS09075 (MDE60_09065) 1888954..1889145 - 192 WP_002911395.1 YebW family protein -
MDE60_RS09080 (MDE60_09070) 1889243..1889482 - 240 WP_002911393.1 YebV family protein -
MDE60_RS09085 (MDE60_09075) 1889598..1891031 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T235678 NZ_CP092077:1886454-1886556 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT235678 NZ_CP092077:c1886563-1886418 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References