Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4992305..4992830 Replicon chromosome
Accession NZ_CP092070
Organism Pectobacterium sp. PL64

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HP572_RS22490 Protein ID WP_240584377.1
Coordinates 4992546..4992830 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HP572_RS22485 Protein ID WP_240584376.1
Coordinates 4992305..4992556 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HP572_RS22455 (HP572_22455) 4987345..4987569 + 225 WP_015841426.1 hypothetical protein -
HP572_RS22460 (HP572_22460) 4987578..4987892 + 315 Protein_4396 ash family protein -
HP572_RS22465 (HP572_22465) 4987925..4988122 + 198 WP_121266703.1 host cell division inhibitor Icd-like protein -
HP572_RS22470 (HP572_22470) 4988115..4988327 + 213 WP_240585808.1 hypothetical protein -
HP572_RS22475 (HP572_22475) 4988338..4990665 + 2328 WP_240584374.1 phage/plasmid primase, P4 family -
HP572_RS22480 (HP572_22480) 4990990..4991952 + 963 WP_240584375.1 hypothetical protein -
HP572_RS22485 (HP572_22485) 4992305..4992556 + 252 WP_240584376.1 prevent-host-death protein Antitoxin
HP572_RS22490 (HP572_22490) 4992546..4992830 + 285 WP_240584377.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HP572_RS22495 (HP572_22495) 4993531..4993959 + 429 WP_240584378.1 GNAT family N-acetyltransferase -
HP572_RS22500 (HP572_22500) 4994050..4995171 + 1122 WP_240584379.1 cupin domain-containing protein -
HP572_RS22505 (HP572_22505) 4995458..4996595 + 1138 Protein_4405 lipase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10982.86 Da        Isoelectric Point: 9.6745

>T235642 WP_240584377.1 NZ_CP092070:4992546-4992830 [Pectobacterium sp. PL64]
MSYKLEFEEHALKEFKKLGAPVREQFTIKLKEVLQNPHVPANRLHGMADCYKIELRSAGYRLVYQVLEHEIVVLVLAVGK
RERSDVYKTAKDRL

Download         Length: 285 bp

>T235642 NZ_LR134315:1766705-1766956 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9077.47 Da        Isoelectric Point: 9.8522

>AT235642 WP_240584376.1 NZ_CP092070:4992305-4992556 [Pectobacterium sp. PL64]
MSVQPILANAAVSISDFKKSPNAALKKANGKPVAVLTNGRISGYYVSPETWEALADYQEDIELAKIARSRMKGKRVKVDL
DEL

Download         Length: 252 bp

>AT235642 NZ_LR134315:1766953-1767207 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References