235638

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) sdenTA/AbiEii(toxin)
Location 4301777..4303217 Replicon chromosome
Accession NZ_CP092070
Organism Pectobacterium sp. PL64

Toxin (Protein)


Gene name sdenT Uniprot ID -
Locus tag HP572_RS19355 Protein ID WP_240584067.1
Coordinates 4301777..4302664 (-) Length 296 a.a.

Antitoxin (Protein)


Gene name sdenA Uniprot ID -
Locus tag HP572_RS19360 Protein ID WP_240584068.1
Coordinates 4302693..4303217 (-) Length 175 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HP572_RS19335 (HP572_19335) 4297762..4298583 + 822 WP_014913737.1 M55 family metallopeptidase -
HP572_RS19340 (HP572_19340) 4298643..4299590 + 948 WP_240584065.1 isoaspartyl peptidase/L-asparaginase -
HP572_RS19345 (HP572_19345) 4299803..4300711 + 909 WP_039474568.1 LysR family transcriptional regulator -
HP572_RS19350 (HP572_19350) 4300810..4301673 + 864 WP_240584066.1 YicC/YloC family endoribonuclease -
HP572_RS19355 (HP572_19355) 4301777..4302664 - 888 WP_240584067.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
HP572_RS19360 (HP572_19360) 4302693..4303217 - 525 WP_240584068.1 hypothetical protein Antitoxin
HP572_RS19365 (HP572_19365) 4303338..4303661 + 324 Protein_3794 YicC family protein -
HP572_RS19370 (HP572_19370) 4304274..4304540 + 267 WP_240584069.1 hypothetical protein -
HP572_RS19375 (HP572_19375) 4304696..4306114 + 1419 WP_240584070.1 Fic family protein -
HP572_RS19380 (HP572_19380) 4306147..4306287 + 141 WP_226308310.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
HP572_RS19385 (HP572_19385) 4306440..4306997 + 558 WP_240584071.1 hypothetical protein -
HP572_RS19390 (HP572_19390) 4307043..4307588 - 546 WP_240584072.1 hypothetical protein -
HP572_RS19395 (HP572_19395) 4307715..4308101 + 387 WP_240584073.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(36-265)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 296 a.a.        Molecular weight: 33978.94 Da        Isoelectric Point: 5.7136

>T235638 WP_240584067.1 NZ_CP092070:c4302664-4301777 [Pectobacterium sp. PL64]
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIMDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFKPSAFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKISIVKEANRPDLPRQKMHIDVCAIPSFDIEKRPLINHYDIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIVWIKQRGIDLSKTLVEKKLTARQKQTEDFRQALSIQLAKLMSEDE
VRDDFNMEMSRFIPKPIKERTLDNPEYWAYVQGEVHAIASELLNDGAPKNPFDMG

Download         Length: 888 bp

>T235638 NZ_LR134315:876802-877215 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGACGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATCAAGATGA

Antitoxin


Download         Length: 175 a.a.        Molecular weight: 19368.48 Da        Isoelectric Point: 9.0504

>AT235638 WP_240584068.1 NZ_CP092070:c4303217-4302693 [Pectobacterium sp. PL64]
MAKSDELLNALAKAVNAGGGIHSVTELAFMQGVPCDSAFRKFLADCVKKGLLRRVVKGFYESVITPPEPETAIYKIIKKL
RSGTLNYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIEFTHTKKPVEQIAPNLYYDPDIKMYRAYKEQAIA
DLKHCQRNLHMLES

Download         Length: 525 bp

>AT235638 NZ_LR134315:876555-876821 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References