Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 3565384..3566024 Replicon chromosome
Accession NZ_CP092070
Organism Pectobacterium sp. PL64

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag HP572_RS15990 Protein ID WP_205551551.1
Coordinates 3565384..3565800 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag HP572_RS15995 Protein ID WP_095700536.1
Coordinates 3565797..3566024 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HP572_RS15970 (HP572_15970) 3561028..3562362 + 1335 WP_240583722.1 type I-F CRISPR-associated protein Csy1 -
HP572_RS15975 (HP572_15975) 3562359..3563291 + 933 WP_240583723.1 type I-F CRISPR-associated protein Csy2 -
HP572_RS15980 (HP572_15980) 3563305..3564315 + 1011 WP_240583724.1 type I-F CRISPR-associated protein Csy3 -
HP572_RS15985 (HP572_15985) 3564325..3564879 + 555 WP_240583725.1 type I-F CRISPR-associated endoribonuclease Cas6/Csy4 -
HP572_RS15990 (HP572_15990) 3565384..3565800 - 417 WP_205551551.1 type II toxin-antitoxin system VapC family toxin Toxin
HP572_RS15995 (HP572_15995) 3565797..3566024 - 228 WP_095700536.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
HP572_RS16000 (HP572_16000) 3567113..3567532 - 420 WP_240583726.1 secondary thiamine-phosphate synthase enzyme YjbQ -
HP572_RS16005 (HP572_16005) 3567548..3570382 - 2835 WP_240583727.1 excinuclease ABC subunit UvrA -
HP572_RS16010 (HP572_16010) 3570457..3570651 + 195 WP_182912385.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-129)

Antitoxin

SpoVT-AbrB domain

(7-55)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15205.74 Da        Isoelectric Point: 9.3444

>T235637 WP_205551551.1 NZ_CP092070:c3565800-3565384 [Pectobacterium sp. PL64]
VSRLFMLDTNICSFIMREHPTAVIDKLQQCTLRRDRIVVSAITYAEMRFGAVGKKASPRHMQLVDAFCRRLDAVLPWDSA
AVDATTKIKIALAAAGTPIGPNDTAIAGHAISAKAILVTNNLREFERVQGLTLEDWVK

Download         Length: 417 bp

>T235637 NZ_LR134315:679898-680218 [Escherichia coli]
ATGCAAATCTCAACTGTACCGGCCACGTTGCCGGTTTCGTCACGCCTGTCACCTGTGCAGGTCTGGCAGCAACTTTTAAC
GTATCTGCTGGAGCAGCATTACGGCCTGACACTCAACGACACGCCATTCCACGATGATTCAGCTATTCATGAGCACATCG
AAGCGGGAATAACGCTTGCTGATGCGGTGAATTTCTTGGTGGAACGCTATGAACTGATACGTACTGACCGCAAAGGATTC
ACCTGGCAGGAGCAAACGCCGTTCCTGACCGCTACCGATATTCTCAGAGCAAGGCGAGCTACCGGATTAATGAATACTTA
A

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8908.08 Da        Isoelectric Point: 4.5216

>AT235637 WP_095700536.1 NZ_CP092070:c3566024-3565797 [Pectobacterium sp. PL64]
MRIVSVFKNGNNRAIRLPRDMDFEGVNELEIVREGDTIMLRPVKPNWHSFLQEERADADFMTERQDIVEEGRFEL

Download         Length: 228 bp

>AT235637 NZ_LR134315:679495-679830 [Escherichia coli]
ATGAATAAAGACGCGCCCCAAATCTGGGGTCTTAAACGAGATATCACACCATGCTTCGGAGCCCGACTGGTGCAGGAAGG
CAACCGTCTGCATTTTCTGGCAGACCGGGCAGGATTCACCGGCTCATTCAGCGAGATGCTTGCCCTACAACTGGATGAAG
CCTTCGCGCATTTTGTCGCACATCTGGAGCTGATGCTGCTCTCCGGCGAGTTGAATCCCCGGTGCGCACACTGTGCCACG
TTGTACCGTAACGGACTGACTTGTGAAGCCGATACGCTGGGCAGTCATGGGTACGTGTATATCGCAATTTATCCATCAAA
TCAGGTTAAAGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References