235636

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 3052936..3053599 Replicon chromosome
Accession NZ_CP092070
Organism Pectobacterium sp. PL64

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag HP572_RS13745 Protein ID WP_010279985.1
Coordinates 3052936..3053280 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag HP572_RS13750 Protein ID WP_039538898.1
Coordinates 3053282..3053599 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HP572_RS13720 (HP572_13720) 3048103..3048402 - 300 Protein_2703 YciI family protein -
HP572_RS13725 (HP572_13725) 3048442..3049065 - 624 WP_240583507.1 FMN-dependent NADH-azoreductase -
HP572_RS13730 (HP572_13730) 3049100..3049873 - 774 WP_240583508.1 alpha/beta hydrolase -
HP572_RS13735 (HP572_13735) 3050038..3051066 + 1029 WP_240583509.1 helix-turn-helix domain-containing protein -
HP572_RS13740 (HP572_13740) 3051177..3052646 + 1470 WP_240583510.1 SEL1-like repeat protein -
HP572_RS13745 (HP572_13745) 3052936..3053280 + 345 WP_010279985.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HP572_RS13750 (HP572_13750) 3053282..3053599 + 318 WP_039538898.1 helix-turn-helix transcriptional regulator Antitoxin
HP572_RS13755 (HP572_13755) 3053688..3053903 - 216 WP_010279992.1 helix-turn-helix transcriptional regulator -
HP572_RS13760 (HP572_13760) 3054500..3054982 + 483 WP_240583511.1 hypothetical protein -
HP572_RS13765 (HP572_13765) 3054979..3055326 + 348 WP_240583512.1 TIR domain-containing protein -
HP572_RS13770 (HP572_13770) 3056031..3057581 + 1551 WP_240583513.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(34-86)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12373.09 Da        Isoelectric Point: 9.7825

>T235636 WP_010279985.1 NZ_CP092070:3052936-3053280 [Pectobacterium sp. PL64]
MKSLYWVGSSKKDLQSLPADVQDVFGYALHVAQTGGKHTQAKPLKGFGGAGVLEVVEDYIGDTYRAVYTVKFGEAVYVLH
AFQKKSSSGIATPKPDMNTIRERLKTAENHAKGA

Download         Length: 345 bp

>T235636 NZ_LR134315:636845-637159 [Escherichia coli]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11448.48 Da        Isoelectric Point: 10.6133

>AT235636 WP_039538898.1 NZ_CP092070:3053282-3053599 [Pectobacterium sp. PL64]
MSQDIEVSSGNVYADLGNLHAEDMLVKAQLATLISSIIKSRRLTQAEAAKLLGMPQPKLSNLLRGQFRGISETKMLECLT
KLGRDIQIVVGKPRRTPGSVKVVFA

Download         Length: 318 bp

>AT235636 NZ_LR134315:637156-637572 [Escherichia coli]
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACACCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTGCTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTGCCGGAAATTGGCAGTAAATCTATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAATTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References