Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | VII | Classification (family/domain) | HepT-MntA/HepT(toxin) |
Location | 971586..972385 | Replicon | chromosome |
Accession | NZ_CP092070 | ||
Organism | Pectobacterium sp. PL64 |
Toxin (Protein)
Gene name | hepT | Uniprot ID | - |
Locus tag | HP572_RS04260 | Protein ID | WP_102116605.1 |
Coordinates | 971586..972005 (-) | Length | 140 a.a. |
Antitoxin (Protein)
Gene name | mntA | Uniprot ID | - |
Locus tag | HP572_RS04265 | Protein ID | WP_240584843.1 |
Coordinates | 972002..972385 (-) | Length | 128 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HP572_RS04240 (HP572_04240) | 966688..967329 | + | 642 | WP_010281304.1 | uridine kinase | - |
HP572_RS04245 (HP572_04245) | 967437..968018 | + | 582 | WP_005974037.1 | dCTP deaminase | - |
HP572_RS04250 (HP572_04250) | 968082..969917 | + | 1836 | WP_240584842.1 | outer membrane assembly protein AsmA | - |
HP572_RS04255 (HP572_04255) | 970182..971534 | + | 1353 | WP_039287778.1 | anaerobic C4-dicarboxylate transporter DcuC | - |
HP572_RS04260 (HP572_04260) | 971586..972005 | - | 420 | WP_102116605.1 | DUF86 domain-containing protein | Toxin |
HP572_RS04265 (HP572_04265) | 972002..972385 | - | 384 | WP_240584843.1 | nucleotidyltransferase domain-containing protein | Antitoxin |
HP572_RS04270 (HP572_04270) | 972521..974107 | - | 1587 | WP_205552438.1 | TerC family protein | - |
HP572_RS04275 (HP572_04275) | 974836..975888 | + | 1053 | WP_240584844.1 | UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase | - |
HP572_RS04280 (HP572_04280) | 976033..977169 | + | 1137 | WP_240584845.1 | polysaccharide export protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 140 a.a. Molecular weight: 16072.40 Da Isoelectric Point: 6.8627
>T235633 WP_102116605.1 NZ_CP092070:c972005-971586 [Pectobacterium sp. PL64]
MTDILLNKSSTIQRCLRRIREEFDTEEGFRQNFTKQDSVILNIQRACEAAIDIANYLIRIKQLGIPQSSRDSFALLAANQ
IITIDLSDNLQKMVGLRNIAVHDYQALNLDIVIHVISHRLSDFERFIKEIARYSDSQHL
MTDILLNKSSTIQRCLRRIREEFDTEEGFRQNFTKQDSVILNIQRACEAAIDIANYLIRIKQLGIPQSSRDSFALLAANQ
IITIDLSDNLQKMVGLRNIAVHDYQALNLDIVIHVISHRLSDFERFIKEIARYSDSQHL
Download Length: 420 bp
>T235633 NZ_LR134314:1067095-1067430 [Streptococcus pyogenes]
TTGGACTATAAGAAATATCAGATTATCTATGCTCCTGATGTTTTAGAGAAGCTAAAAGAAATTCGTGATTATATTTCTCA
AAACTATTCCTCAACATCAGGTCAGCGTAAAATGGAGCAAATCATTAGCGACATAGAAAAACTCGAGGTTTTCCCAGAAG
TTGGTTTTGATGCCGATGAAAAATATGGTTCAAAAATCATCCATTATCACAGCACTAAAGGTTATACCTTAAGTAAAGAT
TATATTGTCCTATACCATATCGAGGGGGAAGAAAATAGGGTCGTTATTGATTACTTGCTTCCTACTCAAAGCGACTATAT
AAAGTTATTCAAATAA
TTGGACTATAAGAAATATCAGATTATCTATGCTCCTGATGTTTTAGAGAAGCTAAAAGAAATTCGTGATTATATTTCTCA
AAACTATTCCTCAACATCAGGTCAGCGTAAAATGGAGCAAATCATTAGCGACATAGAAAAACTCGAGGTTTTCCCAGAAG
TTGGTTTTGATGCCGATGAAAAATATGGTTCAAAAATCATCCATTATCACAGCACTAAAGGTTATACCTTAAGTAAAGAT
TATATTGTCCTATACCATATCGAGGGGGAAGAAAATAGGGTCGTTATTGATTACTTGCTTCCTACTCAAAGCGACTATAT
AAAGTTATTCAAATAA
Antitoxin
Download Length: 128 a.a. Molecular weight: 14372.55 Da Isoelectric Point: 4.7434
>AT235633 WP_240584843.1 NZ_CP092070:c972385-972002 [Pectobacterium sp. PL64]
MFDEIVLTLKKQMPDIKMIYLFGSQATGNARADSDVDIAIMATRALDPVERWELSHQLAKTVGHDVDLIDLLQASTVLKM
EIVRNGKLLYDAEATAGEFEMTTLSMYQHLQKERADIIRSFNQDLKA
MFDEIVLTLKKQMPDIKMIYLFGSQATGNARADSDVDIAIMATRALDPVERWELSHQLAKTVGHDVDLIDLLQASTVLKM
EIVRNGKLLYDAEATAGEFEMTTLSMYQHLQKERADIIRSFNQDLKA
Download Length: 384 bp
>AT235633 NZ_LR134314:1066818-1067105 [Streptococcus pyogenes]
ATGACTACAGTAAAAAAAAACAGAGCGGTTACCTTTCAAGCTAATAAAGAATTGGTAAGCGAAGCAATGACAGTATTAAA
CAAAAAAAATTTAACCTTATCATCTGCTTTAAGATTATTCCTACAAAATGTCGTTGTCACAAACGAGGTTGACTTATTGA
CGGAAGAGGAGTTAGAGAAAGAAAAACTTTTCAAACAATTTCAAGCTGAAATCAACAAAAATATTGAGGATGTTCGTCAA
GGGAAGTTTTATACCTCTGAAGAAGTGAGGGCTGAACTTGGACTATAA
ATGACTACAGTAAAAAAAAACAGAGCGGTTACCTTTCAAGCTAATAAAGAATTGGTAAGCGAAGCAATGACAGTATTAAA
CAAAAAAAATTTAACCTTATCATCTGCTTTAAGATTATTCCTACAAAATGTCGTTGTCACAAACGAGGTTGACTTATTGA
CGGAAGAGGAGTTAGAGAAAGAAAAACTTTTCAAACAATTTCAAGCTGAAATCAACAAAAATATTGAGGATGTTCGTCAA
GGGAAGTTTTATACCTCTGAAGAAGTGAGGGCTGAACTTGGACTATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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