Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 971586..972385 Replicon chromosome
Accession NZ_CP092070
Organism Pectobacterium sp. PL64

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag HP572_RS04260 Protein ID WP_102116605.1
Coordinates 971586..972005 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag HP572_RS04265 Protein ID WP_240584843.1
Coordinates 972002..972385 (-) Length 128 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HP572_RS04240 (HP572_04240) 966688..967329 + 642 WP_010281304.1 uridine kinase -
HP572_RS04245 (HP572_04245) 967437..968018 + 582 WP_005974037.1 dCTP deaminase -
HP572_RS04250 (HP572_04250) 968082..969917 + 1836 WP_240584842.1 outer membrane assembly protein AsmA -
HP572_RS04255 (HP572_04255) 970182..971534 + 1353 WP_039287778.1 anaerobic C4-dicarboxylate transporter DcuC -
HP572_RS04260 (HP572_04260) 971586..972005 - 420 WP_102116605.1 DUF86 domain-containing protein Toxin
HP572_RS04265 (HP572_04265) 972002..972385 - 384 WP_240584843.1 nucleotidyltransferase domain-containing protein Antitoxin
HP572_RS04270 (HP572_04270) 972521..974107 - 1587 WP_205552438.1 TerC family protein -
HP572_RS04275 (HP572_04275) 974836..975888 + 1053 WP_240584844.1 UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase -
HP572_RS04280 (HP572_04280) 976033..977169 + 1137 WP_240584845.1 polysaccharide export protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(13-130)

Antitoxin

Polymerase beta, nucleotidyltransferase

(5-93)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16072.40 Da        Isoelectric Point: 6.8627

>T235633 WP_102116605.1 NZ_CP092070:c972005-971586 [Pectobacterium sp. PL64]
MTDILLNKSSTIQRCLRRIREEFDTEEGFRQNFTKQDSVILNIQRACEAAIDIANYLIRIKQLGIPQSSRDSFALLAANQ
IITIDLSDNLQKMVGLRNIAVHDYQALNLDIVIHVISHRLSDFERFIKEIARYSDSQHL

Download         Length: 420 bp

>T235633 NZ_LR134314:1067095-1067430 [Streptococcus pyogenes]
TTGGACTATAAGAAATATCAGATTATCTATGCTCCTGATGTTTTAGAGAAGCTAAAAGAAATTCGTGATTATATTTCTCA
AAACTATTCCTCAACATCAGGTCAGCGTAAAATGGAGCAAATCATTAGCGACATAGAAAAACTCGAGGTTTTCCCAGAAG
TTGGTTTTGATGCCGATGAAAAATATGGTTCAAAAATCATCCATTATCACAGCACTAAAGGTTATACCTTAAGTAAAGAT
TATATTGTCCTATACCATATCGAGGGGGAAGAAAATAGGGTCGTTATTGATTACTTGCTTCCTACTCAAAGCGACTATAT
AAAGTTATTCAAATAA

Antitoxin


Download         Length: 128 a.a.        Molecular weight: 14372.55 Da        Isoelectric Point: 4.7434

>AT235633 WP_240584843.1 NZ_CP092070:c972385-972002 [Pectobacterium sp. PL64]
MFDEIVLTLKKQMPDIKMIYLFGSQATGNARADSDVDIAIMATRALDPVERWELSHQLAKTVGHDVDLIDLLQASTVLKM
EIVRNGKLLYDAEATAGEFEMTTLSMYQHLQKERADIIRSFNQDLKA

Download         Length: 384 bp

>AT235633 NZ_LR134314:1066818-1067105 [Streptococcus pyogenes]
ATGACTACAGTAAAAAAAAACAGAGCGGTTACCTTTCAAGCTAATAAAGAATTGGTAAGCGAAGCAATGACAGTATTAAA
CAAAAAAAATTTAACCTTATCATCTGCTTTAAGATTATTCCTACAAAATGTCGTTGTCACAAACGAGGTTGACTTATTGA
CGGAAGAGGAGTTAGAGAAAGAAAAACTTTTCAAACAATTTCAAGCTGAAATCAACAAAAATATTGAGGATGTTCGTCAA
GGGAAGTTTTATACCTCTGAAGAAGTGAGGGCTGAACTTGGACTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References