Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 303220..303745 Replicon chromosome
Accession NZ_CP092070
Organism Pectobacterium sp. PL64

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HP572_RS01360 Protein ID WP_240584377.1
Coordinates 303220..303504 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HP572_RS01365 Protein ID WP_240584376.1
Coordinates 303494..303745 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HP572_RS01335 (HP572_01335) 299017..299799 - 783 WP_240584569.1 transporter substrate-binding domain-containing protein -
HP572_RS01340 (HP572_01340) 300168..300746 - 579 WP_240584570.1 hypothetical protein -
HP572_RS01345 (HP572_01345) 301002..302189 - 1188 WP_240584571.1 hypothetical protein -
HP572_RS01350 (HP572_01350) 302191..302499 - 309 Protein_261 tyrosine-type recombinase/integrase -
HP572_RS01355 (HP572_01355) 302480..302709 - 230 Protein_262 hypothetical protein -
HP572_RS01360 (HP572_01360) 303220..303504 - 285 WP_240584377.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HP572_RS01365 (HP572_01365) 303494..303745 - 252 WP_240584376.1 prevent-host-death protein Antitoxin
HP572_RS01370 (HP572_01370) 304228..304557 + 330 WP_240584572.1 DUF1493 family protein -
HP572_RS01380 (HP572_01380) 305266..305748 - 483 WP_010282425.1 SsrA-binding protein SmpB -
HP572_RS01385 (HP572_01385) 305904..306350 + 447 WP_010282427.1 type II toxin-antitoxin system RatA family toxin -
HP572_RS01390 (HP572_01390) 306331..306621 + 291 WP_039274990.1 RnfH family protein -
HP572_RS01395 (HP572_01395) 306860..307195 - 336 WP_120358274.1 outer membrane protein assembly factor BamE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10982.86 Da        Isoelectric Point: 9.6745

>T235631 WP_240584377.1 NZ_CP092070:c303504-303220 [Pectobacterium sp. PL64]
MSYKLEFEEHALKEFKKLGAPVREQFTIKLKEVLQNPHVPANRLHGMADCYKIELRSAGYRLVYQVLEHEIVVLVLAVGK
RERSDVYKTAKDRL

Download         Length: 285 bp

>T235631 NZ_LR134313:c1850784-1850308 [Neisseria canis]
ATGGAAAAATTGACAGCTCCCCAACTTCTGAGTGAAATGCATGTGATAGATGGCTTTGATTGTGGTATCGCATCGCTCAA
CGAGTGGTTGGTAAAAAATGCCCTTAAAAATCAATACAGCAATGCAAGCCGTACTTTTGTTGTCTGTGATCAAGAACAAA
CTGTTTTAGGTTATTACTGCTTGGCAGCAGGCTCTCTAACCCATGAAGAAGCAATCGGAGCGATTCGTCGAAATATGCCC
TCTCCTATTCCCATTATTGTTTTAGGTAGATTGGCCGTCGATTTTCGTGCACAGGGTAAAGAGCTGGGTAAAAGTCTACT
GCGCGATGCCGTATTAAGATCCCAAAATATCAGTCAGCAATTAGGGGCGCGGGCATTATTAGTACACGCCATCAGTGAAG
AAGCTAAACGGTTTTATCTGAAATACGGATTCAAATCCTCCGAGCTATCACCTTATACACTTATGAGAAAATTATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9077.47 Da        Isoelectric Point: 9.8522

>AT235631 WP_240584376.1 NZ_CP092070:c303745-303494 [Pectobacterium sp. PL64]
MSVQPILANAAVSISDFKKSPNAALKKANGKPVAVLTNGRISGYYVSPETWEALADYQEDIELAKIARSRMKGKRVKVDL
DEL

Download         Length: 252 bp

>AT235631 NZ_LR134313:c1851056-1850790 [Neisseria canis]
ATGTTGAAAACAGCACCAATTAATTTGAGGGCACTGGAAAGTCAAAAAAAACTGATTGATCAAGCTGCCGCCCTATCGGG
GAAAACACGTTCAGAATTTATCTTAGAAGCTTCTTGTTCTGCCGCAGAAAACACCCTATTGGAAAAAACCTTTTTCATTC
TGCCAATAGATAAATACAAGCAATTCATTAATCTATTAGAACAGCCGACTGACAACAATGAAGGCTTCGAGAGACTTATG
CAGACAACCCCGGTTTGGGAGCGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References