Detailed information of TA system TA235631

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 303220..303745
• Replicon: chromosome
• Accession: NZ_CP092070
• Organism: Pectobacterium sp. PL64

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HP572_RS01360
• Protein ID: WP_240584377.1
• Coordinates: 303220..303504 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HP572_RS01365
• Protein ID: WP_240584376.1
• Coordinates: 303494..303745 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HP572_RS01335 (HP572_01335)	299017..299799	-	783	WP_240584569.1	transporter substrate-binding domain-containing protein	-
HP572_RS01340 (HP572_01340)	300168..300746	-	579	WP_240584570.1	hypothetical protein	-
HP572_RS01345 (HP572_01345)	301002..302189	-	1188	WP_240584571.1	hypothetical protein	-
HP572_RS01350 (HP572_01350)	302191..302499	-	309	Protein_261	tyrosine-type recombinase/integrase	-
HP572_RS01355 (HP572_01355)	302480..302709	-	230	Protein_262	hypothetical protein	-
HP572_RS01360 (HP572_01360)	303220..303504	-	285	WP_240584377.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HP572_RS01365 (HP572_01365)	303494..303745	-	252	WP_240584376.1	prevent-host-death protein	Antitoxin
HP572_RS01370 (HP572_01370)	304228..304557	+	330	WP_240584572.1	DUF1493 family protein	-
HP572_RS01380 (HP572_01380)	305266..305748	-	483	WP_010282425.1	SsrA-binding protein SmpB	-
HP572_RS01385 (HP572_01385)	305904..306350	+	447	WP_010282427.1	type II toxin-antitoxin system RatA family toxin	-
HP572_RS01390 (HP572_01390)	306331..306621	+	291	WP_039274990.1	RnfH family protein	-
HP572_RS01395 (HP572_01395)	306860..307195	-	336	WP_120358274.1	outer membrane protein assembly factor BamE	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10982.86 Da
• Isoelectric Point: 9.6745

>T235631 WP_240584377.1 NZ_CP092070:c303504-303220 [Pectobacterium sp. PL64]
MSYKLEFEEHALKEFKKLGAPVREQFTIKLKEVLQNPHVPANRLHGMADCYKIELRSAGYRLVYQVLEHEIVVLVLAVGK
RERSDVYKTAKDRL

Nucleotide

• Length: 285 bp

>T235631 NZ_LR134313:c1850784-1850308 [Neisseria canis]
ATGGAAAAATTGACAGCTCCCCAACTTCTGAGTGAAATGCATGTGATAGATGGCTTTGATTGTGGTATCGCATCGCTCAA
CGAGTGGTTGGTAAAAAATGCCCTTAAAAATCAATACAGCAATGCAAGCCGTACTTTTGTTGTCTGTGATCAAGAACAAA
CTGTTTTAGGTTATTACTGCTTGGCAGCAGGCTCTCTAACCCATGAAGAAGCAATCGGAGCGATTCGTCGAAATATGCCC
TCTCCTATTCCCATTATTGTTTTAGGTAGATTGGCCGTCGATTTTCGTGCACAGGGTAAAGAGCTGGGTAAAAGTCTACT
GCGCGATGCCGTATTAAGATCCCAAAATATCAGTCAGCAATTAGGGGCGCGGGCATTATTAGTACACGCCATCAGTGAAG
AAGCTAAACGGTTTTATCTGAAATACGGATTCAAATCCTCCGAGCTATCACCTTATACACTTATGAGAAAATTATAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9077.47 Da
• Isoelectric Point: 9.8522

>AT235631 WP_240584376.1 NZ_CP092070:c303745-303494 [Pectobacterium sp. PL64]
MSVQPILANAAVSISDFKKSPNAALKKANGKPVAVLTNGRISGYYVSPETWEALADYQEDIELAKIARSRMKGKRVKVDL
DEL

Nucleotide

• Length: 252 bp

>AT235631 NZ_LR134313:c1851056-1850790 [Neisseria canis]
ATGTTGAAAACAGCACCAATTAATTTGAGGGCACTGGAAAGTCAAAAAAAACTGATTGATCAAGCTGCCGCCCTATCGGG
GAAAACACGTTCAGAATTTATCTTAGAAGCTTCTTGTTCTGCCGCAGAAAACACCCTATTGGAAAAAACCTTTTTCATTC
TGCCAATAGATAAATACAAGCAATTCATTAATCTATTAGAACAGCCGACTGACAACAATGAAGGCTTCGAGAGACTTATG
CAGACAACCCCGGTTTGGGAGCGTTGA