Detailed information of TA system TA235548

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): hipBA/HipA-HipB
• Location: 5028803..5030391
• Replicon: chromosome
• Accession: NZ_CP092039
• Organism: Pectobacterium brasiliense strain 130

Toxin (Protein)

• Gene name: hipA
• Uniprot ID: -
• Locus tag: MBA20_RS22195
• Protein ID: WP_119870763.1
• Coordinates: 5029072..5030391 (+)
• Length: 440 a.a.

Antitoxin (Protein)

• Gene name: hipB
• Uniprot ID: -
• Locus tag: MBA20_RS22190
• Protein ID: WP_103943261.1
• Coordinates: 5028803..5029072 (+)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• HipA, N-terminal subdomain 1 (4-103)

Antitoxin

• Cro/C1-type helix-turn-helix domain (14-66)

Sequences

Toxin

Protein

• Length: 440 a.a.
• Molecular weight: 49397.67 Da
• Isoelectric Point: 6.6897

>T235548 WP_119870763.1 NZ_CP092039:5029072-5030391 [Pectobacterium brasiliense]
MAALDVYMNGYRVGILTKTGSGAHHFSYDTNWLGLLGSRPISLSMPLRHQPYQGDEVYNFFDNLLPDNPDIRRRIVARHH
TDSTQPFDLLAKVGQDSVGALQLVPQGTPVHDIKKIEYKTLSEQQLENILTGYLSDAPLGMIDTEDDFRISIAGAQEKTA
LLYLDDRWCLPLNVTPTTHIIKLPIGKIESHSYSIDMSDSVENEYLCLLIAKAFGLPVPHCFMINAGKIKALAVERFDRK
YASDVSWIMRLPQEDFCQVLNVPSALKYENHGGPGISAIMSFLLGSVYPERDRYRFMQTQVLFWLLAATDGHAKNFSLFI
ESEGRYRLTPFYDILSMYPAMGGRGIDRREAKLAMGLTGSRGKKYAIEQIFPRHFFQTAKVVGFARESMENILAEFAQTV
DTVMTTVGSQLPVDFPTHISEAILAGLQARSRRLMSGWE

Nucleotide

• Length: 1320 bp

>T235548 NZ_LR134303:c2447536-2447237 [Shewanella putrefaciens]
ATGAATAATAAACGCTATAAACTGAGTAGGTTAGCTCAGGCTCACCTACTAAAGATTAAAGACTACACCCTTCAACACTT
TTCTGAGTCGCAGTGGCACAAATACAAACAAAGCCTAATATCCGGCTTGCAAATGTTAGCCAATCACCCCGGATTAGGCA
GAAGCTGCAACGATATTTACCCCAACGGTTTCTACTTTCCTATCGGTAAACACACAGCCTACTTCACCAAAGAAGACGAC
TTTATCCTTATCGTTGCCCTGTTAGGTCAACCACAACTACCCCAAAATCATCTGAAATAG

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 10062.40 Da
• Isoelectric Point: 9.7281

>AT235548 WP_103943261.1 NZ_CP092039:5028803-5029072 [Pectobacterium brasiliense]
MMKITNSKQLSSYLKDVRITQKLSQGKVASKVGIRQDTVSSFEQHPDSTKLETFFKILSALNLELTVTPRNVDTTNNEAS
VASSWKEEW

Nucleotide

• Length: 270 bp

>AT235548 NZ_LR134303:c2447787-2447545 [Shewanella putrefaciens]
ATGCAAACATTAACCGCCAATGACGCCAAACGAAATTTCGGTGAGTTGCTGCTAAACGCTCAACGTGAACCCATCAAGAT
CAGCAAAAACAGTAAAGATGTGGTTGTGGTCATGTCTATCCACGATTACGAACAGCTTGAGGCGATGAAAGCCGACTATC
TGAAGCACTGTTTCAACGCAGCCAAAGAAGATTTAGCGAAGGGCAATGTGGTTGATGGTGAAGATTTTCTTAACGCCCTG
TAG