235545

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 4573414..4573945 Replicon chromosome
Accession NZ_CP092039
Organism Pectobacterium brasiliense strain 130

Toxin (Protein)


Gene name stbE Uniprot ID A0A086EVU3
Locus tag MBA20_RS20060 Protein ID WP_039282785.1
Coordinates 4573414..4573701 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID A0A1V2R9J2
Locus tag MBA20_RS20065 Protein ID WP_039282788.1
Coordinates 4573691..4573945 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MBA20_RS20040 (MBA20_20040) 4568855..4570246 + 1392 WP_039282780.1 outer membrane channel protein TolC -
MBA20_RS20045 (MBA20_20045) 4570517..4571191 + 675 WP_010280216.1 DUF1190 family protein -
MBA20_RS20050 (MBA20_20050) 4571203..4572363 + 1161 WP_039462681.1 glutathionylspermidine synthase family protein -
MBA20_RS20055 (MBA20_20055) 4572431..4573216 - 786 WP_119871053.1 4,5-DOPA dioxygenase extradiol -
MBA20_RS20060 (MBA20_20060) 4573414..4573701 - 288 WP_039282785.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MBA20_RS20065 (MBA20_20065) 4573691..4573945 - 255 WP_039282788.1 plasmid stabilization protein Antitoxin
MBA20_RS20075 (MBA20_20075) 4574770..4575657 - 888 WP_039556326.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
MBA20_RS20080 (MBA20_20080) 4575719..4577737 + 2019 WP_039282794.1 penicillin-binding protein activator -
MBA20_RS20085 (MBA20_20085) 4577695..4578090 + 396 WP_072036118.1 YraN family protein -
MBA20_RS20090 (MBA20_20090) 4578154..4578744 + 591 WP_005975525.1 DnaA initiator-associating protein DiaA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11011.96 Da        Isoelectric Point: 10.7694

>T235545 WP_039282785.1 NZ_CP092039:c4573701-4573414 [Pectobacterium brasiliense]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQIYSDTKGRSA

Download         Length: 288 bp

>T235545 NZ_LR134302:c3924769-3924587 [Achromobacter spanius]
ATGAACAGCCGCGAGATCATCAGACAGCTTCGCCAAGCGGGCTGGGTATTCCGACATGCGAAAGGCTCGCATCACATTTT
CGTCCACCCGCAAAAAGCTGGGCATATCAGCGTGCCTCACCCCAAGAAAGACTTGGGGATCGGACTGGTTACGAAACTGC
TGACGCAAGCCGGCCTGAAGTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9208.38 Da        Isoelectric Point: 3.7947

>AT235545 WP_039282788.1 NZ_CP092039:c4573945-4573691 [Pectobacterium brasiliense]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAVFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Download         Length: 255 bp

>AT235545 NZ_LR134302:c3924537-3924145 [Achromobacter spanius]
ATGAAATATCCAATCGCCATTGAACCCGGCAGCGAGACGCAAGCGTGGGGCGTCGTCGTGCCGGATCTGCCGGGCTGCTT
TTCCGCCGCCGACTCAGGCATAGACGAAGCTATCGAGAACGCAAAAGAAGCGATCGAGCTGTGGATTGAAACCGCGTTGG
ATAGCGGCACACCCGTACCCGTTGCCACCAGCATTGCGGGTCACCAAGCGAATCCGGAATTCGCGGGCTGGGTTTGGGCC
ATTGTTGAAATCGATCCGGCCGTCATGGACGACACCATCGAACGCATCAACATCACGCTGCCCCGCCGAATCCTTGCAAG
GATCGACGCCAAAGCGCGTGCGGCGGGAGAAAGCCGATCTGGCTACATCGCTCATCTGGCATTGACGCACTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A086EVU3

Antitoxin

Source ID Structure
AlphaFold DB A0A1V2R9J2

References