Detailed information of TA system TA235544

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 4479184..4479711
• Replicon: chromosome
• Accession: NZ_CP092039
• Organism: Pectobacterium brasiliense strain 130

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: MBA20_RS19635
• Protein ID: WP_119871082.1
• Coordinates: 4479184..4479459 (-)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: MBA20_RS19640
• Protein ID: WP_119871081.1
• Coordinates: 4479463..4479711 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MBA20_RS19610 (MBA20_19610)	4474342..4475574	+	1233	WP_119871085.1	FtsX-like permease family protein	-
MBA20_RS19615 (MBA20_19615)	4475564..4477099	+	1536	WP_119871084.1	SUMF1/EgtB/PvdO family nonheme iron enzyme	-
MBA20_RS19620 (MBA20_19620)	4477122..4477826	+	705	WP_014913963.1	hypothetical protein	-
MBA20_RS19625 (MBA20_19625)	4477837..4478319	+	483	WP_014913962.1	hypothetical protein	-
MBA20_RS19630 (MBA20_19630)	4478624..4479136	-	513	WP_119871083.1	AAA family ATPase	-
MBA20_RS19635 (MBA20_19635)	4479184..4479459	-	276	WP_119871082.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
MBA20_RS19640 (MBA20_19640)	4479463..4479711	-	249	WP_119871081.1	ribbon-helix-helix domain-containing protein	Antitoxin
MBA20_RS19645 (MBA20_19645)	4479821..4479991	-	171	WP_230857149.1	DUF4942 domain-containing protein	-
MBA20_RS19650 (MBA20_19650)	4480025..4483273	-	3249	WP_119871080.1	DEAD/DEAH box helicase family protein	-
MBA20_RS19655 (MBA20_19655)	4483270..4484619	-	1350	WP_199679142.1	restriction endonuclease subunit S	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	4479184..4493878	14694

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (9-43)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 11046.26 Da
• Isoelectric Point: 5.1631

>T235544 WP_119871082.1 NZ_CP092039:c4479459-4479184 [Pectobacterium brasiliense]
MEIRWTQKAQDDLERIYGFASQYSRQHADEVLDRLIIGTTGLADYPRIGVSQTRYEPREVRKILFDDYEVHYEIQHDTSY
IVDLWHKREDR

Nucleotide

• Length: 276 bp

>T235544 NZ_LR134302:c3738862-3738287 [Achromobacter spanius]
ATGAGGCATTCCCCATTCACCGCCGTCTACGACGCGTGCGTTCTATATCCCGCGCCACTGCGGGATTTCCTGATGTGGCT
CGGCCTGTCTGGCCGCTTCCGGGCGCGGTGGAGCCAAGCCATTCATGAGGAGTGGAAACGCAACCTGTTGATCAACCGCC
CCGATCTCACCCGGGTTCAGGTCGACAGGACGTCGGATCTCATGGACCGGGCAATTCCGGACGGCTTGGTGGAGGGCTAC
GAAGCGCTCGTGGCAGGCCTGACATTGCCCGATCCGGACGACCGGCACGTCCTGGCTGCGGCGATTCGCTGCGGTGCGAG
CGTGATTGTGACGTTCAACGAACGGGATTTCCCGAACGATCTGCTGGCTCCGTACGGCATCGAATCGCAGCACCCCGATG
AGTTTGTGGACAACCTACTGGATCTGGACGCGGCCGCCGTGGTGTCGGCTGCGCAGCGCCAGCGTGCCCAACTCAAGCAT
CCGCCGATCGAGGTGGACCGCTATCTCGAAATCCTGCTGCGCCAGGGCCTTGTGCAAACGACCAAGGTGCTGGCGACCTA
TCGCACCATTCTCTGA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9090.52 Da
• Isoelectric Point: 10.0121

>AT235544 WP_119871081.1 NZ_CP092039:c4479711-4479463 [Pectobacterium brasiliense]
MGQPAKQTISAQIPAELAAAVERLAIELDRSKSWVIKEALTAMIEERERRHQRILKGLADVDAGRVVSHADVIDFANKLK
KS

Nucleotide

• Length: 249 bp

>AT235544 NZ_LR134302:c3739329-3738859 [Achromobacter spanius]
ATGACCACCGCCACTGCCCAATCCAAGATGACCCTTCCCGCCGCGGGAGAGGTGAAGGCAGCCGTCCAGGGTCAACGTGC
CTTGGCGGCTTACCTCGCAACCCAGTTCGAGACGCAGCACATCCAGATCTTTGATGACCACAAACAGGCTCATCAGGTGG
AACTGCCTACCTCGGCTTTACGCCTGCTGGTCGACATCCTGGCCGAGTTGGCCGATGGCAATGCAGTAAAGGTGGTGCCC
GTCCATGCAGAGCTGACGACCCAAGAGGCGGCGGACTTGCTCAACGTGTCCCGTCCCCATTTCGTCAAGCTGCTCGAAGA
TGGGGTGTTGGCATTTCATCGCACCGGCAAGCACCGCAGGGTGAGGTTCGCCGATCTGATGCAGTACAAGGAAGCGCGCG
AGCGCGCCAGTGAGCAGGCGATGGCCGAACTCGCTCAGCAGTCGCAAGAGTTGGGAATGGGATACGAATGA