Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 4424157..4424740 Replicon chromosome
Accession NZ_CP092039
Organism Pectobacterium brasiliense strain 130

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag MBA20_RS19415 Protein ID WP_119871112.1
Coordinates 4424157..4424462 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MBA20_RS19420 Protein ID WP_119871111.1
Coordinates 4424450..4424740 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MBA20_RS19400 (MBA20_19400) 4420573..4421532 + 960 WP_039279295.1 ABC transporter permease -
MBA20_RS19405 (MBA20_19405) 4421525..4422391 + 867 WP_010285293.1 ABC transporter permease -
MBA20_RS19410 (MBA20_19410) 4422388..4424097 + 1710 WP_119871113.1 ABC transporter ATP-binding protein -
MBA20_RS19415 (MBA20_19415) 4424157..4424462 - 306 WP_119871112.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MBA20_RS19420 (MBA20_19420) 4424450..4424740 - 291 WP_119871111.1 ribbon-helix-helix protein, CopG family Antitoxin
MBA20_RS19425 (MBA20_19425) 4424802..4425656 - 855 WP_119871110.1 helix-turn-helix domain-containing protein -
MBA20_RS19430 (MBA20_19430) 4425681..4426520 - 840 WP_014913998.1 HTH-type transcriptional activator RhaS -
MBA20_RS19435 (MBA20_19435) 4426857..4428347 + 1491 WP_119871109.1 rhamnulokinase -
MBA20_RS19440 (MBA20_19440) 4428344..4429606 + 1263 WP_039282588.1 L-rhamnose isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-96)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11602.42 Da        Isoelectric Point: 9.4590

>T235543 WP_119871112.1 NZ_CP092039:c4424462-4424157 [Pectobacterium brasiliense]
MPQVIVSERARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVVLYRHDE
LTDRVVILTVKHQKEAGYQNP

Download         Length: 306 bp

>T235543 NZ_LR134302:3582598-3582975 [Achromobacter spanius]
ATGATCTTGGTTGACACGTCGATCTGGATCGATCATCTGGGGGCAAGCGAACCCCGGCTTGAACAGTTGCTCCACAATGA
ATTTGTCCTGATGCACCCGTTCATCGTTGGCGAACTGGCGCTCGGATCGCTGAATAAGCGGGACATGGTGTTGGGCGCAC
TGACGCTTTTGCCACAGGCGGTTCGGGCGAGCCACGACGAGGCAATCCACTTTCTTCATGCCGAACGGCTATTTGGAAAA
GGCATCGGCTATGTCGACCTGCATCTGCTTGCATCGACCCGCCTGACGCCCGGTGCTTCGCTGTGGACCAAAGACAAGCG
GCTGGGATCTCTTGCCAAGACCTTGAACCTGTCTGTCGAGCCCCCGCTATATCATTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11100.17 Da        Isoelectric Point: 4.7845

>AT235543 WP_119871111.1 NZ_CP092039:c4424740-4424450 [Pectobacterium brasiliense]
MADTPRQTTTLRIDQDIKERLKTLADDRHSSAHALMLEAITEYVEREEKRSQYRKEALAAWEEYQSTGEHITADETVTWL
ESWGSGHEQDAPACHK

Download         Length: 291 bp

>AT235543 NZ_LR134302:3582402-3582611 [Achromobacter spanius]
ATGCGTACCACAGTGACGCTCGATGACGATTTGCTCGAGAAAGCGCGAATCTATACGGGCATACAGGAAACCTCTGCGCT
TGTGCAGCAGGCGCTGACGAACCTGGTGCAGAAAGAGGCGGCCAAGCGCCTGGCCAAACTGGGCGGCAGTTCACCCAAAT
TGAAGCCGACGCCACGGCGGCAAACGGAGACACCCGATGATCTTGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References