Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 3730482..3731518 Replicon chromosome
Accession NZ_CP092039
Organism Pectobacterium brasiliense strain 130

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag MBA20_RS16215 Protein ID WP_119871526.1
Coordinates 3730482..3731057 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag MBA20_RS16220 Protein ID WP_119871525.1
Coordinates 3731057..3731518 (-) Length 154 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MBA20_RS16195 (MBA20_16195) 3728345..3728740 - 396 WP_014914413.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
MBA20_RS16200 (MBA20_16200) 3728727..3729182 - 456 WP_230857130.1 YgdB family protein -
MBA20_RS16205 (MBA20_16205) 3729179..3729805 - 627 WP_119871528.1 prepilin peptidase-dependent protein -
MBA20_RS16210 (MBA20_16210) 3729799..3730302 - 504 WP_119871527.1 prepilin peptidase-dependent protein -
MBA20_RS16215 (MBA20_16215) 3730482..3731057 - 576 WP_119871526.1 PIN domain-containing protein Toxin
MBA20_RS16220 (MBA20_16220) 3731057..3731518 - 462 WP_119871525.1 helix-turn-helix domain-containing protein Antitoxin
MBA20_RS16225 (MBA20_16225) 3731741..3732535 - 795 WP_039312476.1 thymidylate synthase -
MBA20_RS16230 (MBA20_16230) 3732572..3733438 - 867 WP_010286783.1 prolipoprotein diacylglyceryl transferase -
MBA20_RS16235 (MBA20_16235) 3733665..3735911 - 2247 WP_039283946.1 phosphoenolpyruvate--protein phosphotransferase -
MBA20_RS16240 (MBA20_16240) 3735924..3736457 - 534 WP_010282870.1 RNA pyrophosphohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-115)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21493.91 Da        Isoelectric Point: 4.7230

>T235539 WP_119871526.1 NZ_CP092039:c3731057-3730482 [Pectobacterium brasiliense]
MNHSPYPVVLDACVIYPSLLRDLLMHLGLTGLYQPKWTVLIQEEWQRNLLLNNADVTMDKLRNIEHLMNKALPDANVTGF
EQLIPALVLPDADDRHVLAAAIRANAEVIVTANLKDFPATSLSEFGVEAMHPDEFIADLFDLNSALVLKAVRTSRTAFRK
PPFDVDEYLDCLLRQGLPMTVKELDAYRALI

Download         Length: 576 bp

>T235539 NZ_LR134302:c246035-245124 [Achromobacter spanius]
ATGAATCCCGCCTTCTCGATACGTGCAAGGCTGCTCACCCATGCCAAACGACACGGGGACGACTTTCAGCGGGTGCTGAC
TCGTTACGCCATTGAGCGACTGCTGTTCCGCCTTAGTCAGACGAAGGTGGGAGAACATTACGTGCTGAAGGGTGCAATGT
TGTTCGTGACTTGGCCCAGATACGTCTTCCGCCCGACCGGCGATCTGGATCTATTGGGGCAGGGAAATTCAGAACCTGCG
GCTCTCGTGGAACTCTTCACTCGCATCTGCCAGGTCGAATGCGTCGCCGACGGTATTGTTTTTGATGCGGCCATGGTGAG
GGTCGAGGCGGTTCGCGAAGCCGACAAGTACCACGGATCTCGCATTAGCCTCGCCGCAGACTTGGCGGGGGCAAGGATCC
CAGTCCAGATTGACGTCGGTTTCGGTGACCGAGTCTATCCGGAACCGAAGCGCGAAATATTTCCGAGCTTAGTGCCTGAC
GTCCCGCATGCCAGCATTTTGATGTATCCACCCGAGACGGTAGTCGCCGAGAAATTTGAGGCGATGATCAGGTTCGGCGA
AACCAATACCCGAATTAAGGACTATTACGACGTATGGGTCACCACTAGGATCTTTCCGTTCGATATGGCCAATGTAGTCG
AGGCCGTCGGTGGAACTCTTCGGCGCCGCGAGACGGCTATTCCGACGGAAATGCCGATGGGGCTTACCAGTACGTTTGCC
GCGATTGTTGATGAACGTGGTCTGTGGTCGGGTTTTCTACGTCGGACCTCCCCAACTCTAACGCCGCCGTCGTTTCCAGA
CCTTCAATCCGAATTGCGAAGTTTTTTCCGCTTAGTTATTGAGGGCCTCAATATGTCCGAAGGTGCTCGAGGAGTGTGGG
ACACGGACGGTAGAGTTTGGCGGAACCGTTAG

Antitoxin


Download         Length: 154 a.a.        Molecular weight: 17277.78 Da        Isoelectric Point: 6.2253

>AT235539 WP_119871525.1 NZ_CP092039:c3731518-3731057 [Pectobacterium brasiliense]
MKNTPLNSLSLPAPKEMEAAIRGQRQLATYLSTKLETQEISIQDAHDIAHRIELPTSALTLLMSILGELAAGNAVQIVPV
QAELTTQEAANILNVSRPHMVKLLEEGHLPFHKTGRHRRVLFADLMQYKEQRENESMQAMQELTDRSQEFGFY

Download         Length: 462 bp

>AT235539 NZ_LR134302:c246655-246041 [Achromobacter spanius]
ATGTCCGAATATCCCATTTCTAATCGCGAACGAGTCCTTCAGCTAGTGAGGGACAGAGGAATCGCGCGCGCGCGTGACCT
TACGGCTGCGGGCATTCCCCTCGCATATCTAAAACGCCTGACCGACAGTGGCGACCTTATCCGTTTGGGTCGCGGTCTCT
ACCAAACACCGGATCGCGTCGGCGAAGATGCCGCCCATGATCTCGCCGAGGCGGCCCGCCGAGTGCCTAAGGGAGTCATT
AGCCTGATCAGTGCTCTTCGCTGGCACGAAGTGACGACGCAACTGCCGAATGCCGTCTGGATGACCATTCCCCACAAGTC
CCGTGTACCTAAGTCAACCGGTCTGAGACTAGAAATTGTGCGCGCCACGGGCGAGACCCTGACCGCCGGCGTCGAATACG
TCGACGTGGAAGGGGTGGCTGTGCCCGTTTACTGCGTTGCCAAGACGGTGGCAGATTGTTTCAAGCATCGGCGTCATGTA
GGTGAGGATGTGGCTATCGAAGCCCTGCGTGACGCCCTGCATCAGCGCAAGGCTACCCCTAGTGACCTTATGAAATTTGC
TGCGATTAACCGGGTCGCCGGTCTAATGGCACCGTATATCAGGGCGATGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References