235536

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 1334924..1335587 Replicon chromosome
Accession NZ_CP092039
Organism Pectobacterium brasiliense strain 130

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag MBA20_RS05945 Protein ID WP_119870726.1
Coordinates 1335243..1335587 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag MBA20_RS05940 Protein ID WP_119870727.1
Coordinates 1334924..1335241 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MBA20_RS05920 (MBA20_05920) 1331461..1333038 + 1578 WP_014916196.1 glutamine-hydrolyzing GMP synthase -
MBA20_RS05925 (MBA20_05925) 1333199..1333546 - 348 WP_119870730.1 TIR domain-containing protein -
MBA20_RS05930 (MBA20_05930) 1333543..1334025 - 483 WP_119870729.1 hypothetical protein -
MBA20_RS05935 (MBA20_05935) 1334622..1334837 + 216 WP_119870728.1 helix-turn-helix transcriptional regulator -
MBA20_RS05940 (MBA20_05940) 1334924..1335241 - 318 WP_119870727.1 helix-turn-helix transcriptional regulator Antitoxin
MBA20_RS05945 (MBA20_05945) 1335243..1335587 - 345 WP_119870726.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MBA20_RS05950 (MBA20_05950) 1335812..1336840 - 1029 WP_119870725.1 helix-turn-helix domain-containing protein -
MBA20_RS05955 (MBA20_05955) 1337008..1337781 + 774 WP_119870724.1 alpha/beta hydrolase -
MBA20_RS05960 (MBA20_05960) 1337817..1338437 + 621 WP_119870723.1 FMN-dependent NADH-azoreductase -
MBA20_RS05965 (MBA20_05965) 1338477..1338785 + 309 WP_014916188.1 YciI family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(34-86)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12393.08 Da        Isoelectric Point: 9.7825

>T235536 WP_119870726.1 NZ_CP092039:c1335587-1335243 [Pectobacterium brasiliense]
MKSLYWVGSSKKDLQSLPADVQDVFGYALHVAQTGGKHTQAKPLKGFGGAGVLEVVEDYIGDTYRAVYTVKFGEAVYVLH
TFQKKSSSGIATPKSDMNTIRERLKTAENHAKGA

Download         Length: 345 bp

>T235536 NZ_LR134300:c4602384-4602106 [Pseudomonas fluorescens]
CTGATTCTGACCTTTCGCTGCGACGAGACTCGTCAGCTTTTTGAGACGGGTCTTTCGAGGCGGTGGGGAGCGATCCTCAC
AGTCGCTACGCGTAAGCTCGCAATGCTTCATGCGGCTACGGAGCTTCGAGACTTGCGCTCTCCACCTGGAAACCGGTTGG
AGCCGTTGCAGGGAAAGCGGGTGGGCCAACATAGCATCAGGATCAATGACCAGTGGCGTGTCTGTTTCGTCTGGACGGAT
GCGGGTCCCGAAGAAGTCGAAATAGTTGATTACCACTGA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11419.48 Da        Isoelectric Point: 10.6133

>AT235536 WP_119870727.1 NZ_CP092039:c1335241-1334924 [Pectobacterium brasiliense]
MSLDIEVSSGNVYADLGNVHAEDMLVKAQLATLISSIIKSRRLTQAEAAKLLGMPQPKLSNLLRGQFRGISETKMLECLT
KLGRDIQIVVGKPRRTPGSVKVVFA

Download         Length: 318 bp

>AT235536 NZ_LR134300:c4602094-4601789 [Pseudomonas fluorescens]
ATGGCTACCAATGGTATGCGCCCCATCCATCCCGGGGAAATATTGCGCGATGAGTTTCTGATGGAGTTGGATATCTCTCC
AGCTGCTCTAGCACGCGCTTTGAAAGTCTCCGCTCCGACAGTGAACGATATCGTTCGTGAGCAGCGTGGTATCTCCGCAG
ATATGGCGATTCGTCTGGGGCGTTACTTTGATACGTCCGCTCAGTTCTGGATGAATCTCCAGAGTGAGTATTCGTTAGCA
ACTGCTTATGCGGCGAATGGCAAGCAGATCGAACATGAGATTGAGCCGCTGCTTGCTCACGGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References