Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 827966..828629 | Replicon | chromosome |
Accession | NZ_CP092014 | ||
Organism | Edwardsiella ictaluri strain 13 TAL-140 K3 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | C5BAS3 |
Locus tag | MAY91_RS04010 | Protein ID | WP_015872556.1 |
Coordinates | 827966..828382 (-) | Length | 139 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | - |
Locus tag | MAY91_RS04015 | Protein ID | WP_049640283.1 |
Coordinates | 828363..828629 (-) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
MAY91_RS03990 (MAY91_03980) | 823889..825623 | - | 1735 | Protein_768 | single-stranded-DNA-specific exonuclease RecJ | - |
MAY91_RS03995 (MAY91_03985) | 825628..826344 | - | 717 | WP_015872553.1 | bifunctional protein-disulfide isomerase/oxidoreductase DsbC | - |
MAY91_RS04000 (MAY91_03990) | 826372..827271 | - | 900 | WP_015872554.1 | site-specific tyrosine recombinase XerD | - |
MAY91_RS04005 (MAY91_03995) | 827429..827941 | + | 513 | WP_015872555.1 | flavodoxin FldB | - |
MAY91_RS04010 (MAY91_04000) | 827966..828382 | - | 417 | WP_015872556.1 | protein YgfX | Toxin |
MAY91_RS04015 (MAY91_04005) | 828363..828629 | - | 267 | WP_049640283.1 | FAD assembly factor SdhE | Antitoxin |
MAY91_RS04020 (MAY91_04010) | 828977..829972 | + | 996 | WP_049640284.1 | tRNA-modifying protein YgfZ | - |
MAY91_RS04025 (MAY91_04015) | 830013..830837 | - | 825 | WP_015872559.1 | shikimate 5-dehydrogenase | - |
MAY91_RS04030 (MAY91_04020) | 830999..831871 | - | 873 | WP_015872560.1 | nucleoside-specific channel-forming protein Tsx | - |
MAY91_RS04035 (MAY91_04025) | 832480..833129 | + | 650 | Protein_777 | hemolysin III family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 139 a.a. Molecular weight: 16145.89 Da Isoelectric Point: 11.3233
>T235488 WP_015872556.1 NZ_CP092014:c828382-827966 [Edwardsiella ictaluri]
VALWRCNVHASWRTQVMFLLGHGALVLAILLAPWPENYSVFWLILLVAVIFECIRSQRLIARNSGELQRLAPQVWHWQLR
EWRLARRPWVSDLGALLILQSTHGTPCRRRLWLAADSMSREEWGQLRRALLDTGDDRV
VALWRCNVHASWRTQVMFLLGHGALVLAILLAPWPENYSVFWLILLVAVIFECIRSQRLIARNSGELQRLAPQVWHWQLR
EWRLARRPWVSDLGALLILQSTHGTPCRRRLWLAADSMSREEWGQLRRALLDTGDDRV
Download Length: 417 bp
>T235488 NZ_LR134295:713600-713896 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCACTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCACTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10306.88 Da Isoelectric Point: 6.4543
>AT235488 WP_049640283.1 NZ_CP092014:c828629-828363 [Edwardsiella ictaluri]
MDINNKARVHWACRRGMRELDIAIMPFFEHEYDALNDADKQTFVRLLSCDDPELFKWLMNQGKPGDTDLARMITLIQTRN
KERGPLAL
MDINNKARVHWACRRGMRELDIAIMPFFEHEYDALNDADKQTFVRLLSCDDPELFKWLMNQGKPGDTDLARMITLIQTRN
KERGPLAL
Download Length: 267 bp
>AT235488 NZ_LR134295:713898-714293 [Escherichia coli]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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