Detailed information of TA system TA023535

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 3096568..3097244
• Replicon: chromosome
• Accession: NC_011989
• Organism: Agrobacterium vitis S4

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: AVI_RS14735
• Protein ID: WP_015917096.1
• Coordinates: 3096568..3096966 (-)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: AVI_RS14740
• Protein ID: WP_139191371.1
• Coordinates: 3096963..3097244 (-)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AVI_RS14725	3092635..3094569	-	1935	WP_015917094.1	HAMP domain-containing protein	-
AVI_RS14730	3094925..3096379	-	1455	WP_015917095.1	glutamate synthase subunit beta	-
AVI_RS31150	3096391..3096549	-	159	WP_156583032.1	hypothetical protein	-
AVI_RS14735	3096568..3096966	-	399	WP_015917096.1	type II toxin-antitoxin system VapC family toxin	Toxin
AVI_RS14740	3096963..3097244	-	282	WP_139191371.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
AVI_RS14745	3097290..3102011	-	4722	WP_015917098.1	glutamate synthase large subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (3-123)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 14727.95 Da
• Isoelectric Point: 5.7917

>T23535 WP_015917096.1 NC_011989:c3096966-3096568 [Agrobacterium vitis S4]
MSYLFDTNAISEFIRNPDGKTAKKVAALKEGELRTSLIVAAELRYGAAKKGSERLVRLIETVLSEFEVMPWEAPADVHYA
ALRDSLSRRGQPIGDMDMLIAAHALALDAVLVTDNEREFSRVPGLKIENWLR

Nucleotide

• Length: 399 bp

>T23535 NC_011989:c3096966-3096568 [Agrobacterium vitis S4]
ATGAGTTACCTGTTCGATACCAACGCGATTTCGGAATTCATCCGAAATCCAGATGGCAAAACCGCGAAAAAGGTCGCTGC
GCTTAAAGAGGGTGAATTGAGAACGAGCCTGATCGTGGCGGCCGAACTGAGATACGGGGCAGCCAAGAAGGGCTCAGAGC
GTTTGGTCCGGCTCATCGAGACAGTTTTGTCCGAATTCGAGGTTATGCCTTGGGAGGCGCCGGCCGATGTTCACTATGCT
GCGCTCAGGGACAGTCTGAGCCGCCGTGGGCAACCGATAGGCGATATGGATATGCTGATTGCGGCACATGCCCTCGCCTT
GGATGCTGTGCTTGTGACGGATAATGAAAGAGAATTTTCCCGGGTTCCGGGATTGAAGATCGAGAATTGGCTGCGATAG

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10563.97 Da
• Isoelectric Point: 4.3224

>AT23535 WP_139191371.1 NC_011989:c3097244-3096963 [Agrobacterium vitis S4]
MEVAMFPISKERRAKIFMNGRSRAVRIPSDFDLSGDEVVIRQEADGVITIQSARQKRSPGGLIEWLRQAEPLGQDFPEID
DQPLQEIDLDLPE

Nucleotide

• Length: 282 bp

>AT23535 NC_011989:c3097244-3096963 [Agrobacterium vitis S4]
ATGGAGGTGGCGATGTTTCCGATATCAAAGGAGCGTAGGGCAAAGATATTCATGAACGGGAGAAGTCGTGCTGTGCGGAT
ACCAAGCGACTTCGATCTCTCCGGAGATGAAGTCGTCATCCGACAGGAGGCGGATGGCGTAATCACCATTCAATCCGCTC
GCCAGAAGCGCTCACCAGGCGGGTTGATAGAGTGGCTTCGGCAAGCGGAACCGCTCGGCCAAGACTTTCCTGAGATAGAT
GATCAGCCTCTTCAGGAGATTGATCTGGATCTTCCCGAATGA