Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 1552076..1552717 Replicon chromosome
Accession NZ_CP091983
Organism Burkholderia vietnamiensis strain FDAARGOS_721

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FOC29_RS07915 Protein ID WP_011881500.1
Coordinates 1552076..1552414 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FOC29_RS07920 Protein ID WP_011881499.1
Coordinates 1552418..1552717 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOC29_RS07905 (FOC29_07900) 1548617..1550050 - 1434 WP_011881502.1 aldehyde dehydrogenase family protein -
FOC29_RS07910 (FOC29_07905) 1550079..1551719 - 1641 WP_011881501.1 acetolactate synthase large subunit -
FOC29_RS07915 (FOC29_07910) 1552076..1552414 + 339 WP_011881500.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FOC29_RS07920 (FOC29_07915) 1552418..1552717 + 300 WP_011881499.1 putative addiction module antidote protein Antitoxin
FOC29_RS07925 (FOC29_07920) 1552798..1554084 - 1287 WP_014724584.1 DUF445 domain-containing protein -
FOC29_RS07930 (FOC29_07925) 1554273..1555493 - 1221 WP_059462396.1 anthranilate 1,2-dioxygenase system ferredoxin--NAD(+) reductase -
FOC29_RS07935 (FOC29_07930) 1555483..1555809 - 327 WP_011881496.1 anthranilate 1,2-dioxygenase ferredoxin subunit AndAb -
FOC29_RS07940 (FOC29_07935) 1555836..1556321 - 486 WP_034194948.1 anthranilate 1,2-dioxygenase small subunit AndAd -
FOC29_RS07945 (FOC29_07940) 1556339..1557610 - 1272 WP_014724582.1 anthranilate 1,2-dioxygenase large subunit AndAc -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(16-106)

Antitoxin

Uncharacterized protein HI1420

(6-93)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12642.42 Da        Isoelectric Point: 9.4958

>T235342 WP_011881500.1 NZ_CP091983:1552076-1552414 [Burkholderia vietnamiensis]
MVDISSNVPYSAPTYSIRTTEVFDTWFAGLQDRVARRRIQARIDRLSMGNPGDWKSAGSPVVEMRIDHGPGYRVYYVRRA
TIWVILLCGGDKSTQQADIRAAHAMLGRLDLE

Download         Length: 339 bp

>T235342 NZ_LR134239:3312860-3313078 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10548.87 Da        Isoelectric Point: 6.0633

>AT235342 WP_011881499.1 NZ_CP091983:1552418-1552717 [Burkholderia vietnamiensis]
MDKISTRPWDSAAHLETDDDIADYFDACLQEGGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGAKARA

Download         Length: 300 bp

>AT235342 NZ_LR134239:3312460-3312834 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTAAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References