Detailed information of TA system TA023531

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-CC2985
• Location: 2185840..2186387
• Replicon: chromosome
• Accession: NC_011989
• Organism: Agrobacterium vitis S4

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: AVI_RS10395
• Protein ID: WP_015916319.1
• Coordinates: 2186085..2186387 (+)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: B9JXB9
• Locus tag: AVI_RS10390
• Protein ID: WP_015916318.1
• Coordinates: 2185840..2186088 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AVI_RS29075	2181670..2183322	-	1653	WP_139192551.1	precorrin-8X methylmutase	-
AVI_RS10375	2183322..2184653	-	1332	WP_015916316.1	sirohydrochlorin chelatase	-
AVI_RS10385	2184990..2185775	+	786	WP_015916317.1	TSUP family transporter	-
AVI_RS10390	2185840..2186088	+	249	WP_015916318.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
AVI_RS10395	2186085..2186387	+	303	WP_015916319.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
AVI_RS10400	2186422..2187066	-	645	WP_015916320.1	cob(I)yrinic acid a,c-diamide adenosyltransferase	-
AVI_RS10405	2187063..2190845	-	3783	WP_015916321.1	cobaltochelatase subunit CobN	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-93)

Antitoxin

• Antitoxin ParD (3-72)

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 11690.42 Da
• Isoelectric Point: 10.2325

>T23531 WP_015916319.1 NC_011989:2186085-2186387 [Agrobacterium vitis S4]
MSGKSYRVTEIARLDVEDIGRYTNKTWGKRQRNDYLRALFIRFEFLAEFPYSGQKHDHIREGLFGFSEGAHVIFYRINAG
GIDILRVLHQRMSLVTAPIK

Nucleotide

• Length: 303 bp

>T23531 NC_011989:2186085-2186387 [Agrobacterium vitis S4]
ATGAGCGGCAAAAGCTATCGGGTCACTGAAATAGCACGTCTCGATGTCGAGGATATCGGTCGTTACACCAACAAAACCTG
GGGCAAGCGTCAGAGAAACGATTATCTACGAGCCTTGTTCATCAGGTTCGAGTTTCTCGCTGAATTTCCCTATTCTGGAC
AAAAGCATGACCACATCAGGGAAGGCCTTTTCGGTTTTTCCGAGGGCGCGCATGTGATCTTTTACCGGATCAATGCCGGT
GGGATCGACATCCTCCGTGTCCTTCATCAGCGCATGAGCCTGGTAACAGCCCCGATCAAATAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9571.62 Da
• Isoelectric Point: 4.8894

>AT23531 WP_015916318.1 NC_011989:2185840-2186088 [Agrobacterium vitis S4]
MATTSLTLGPHWEGFIKQQISSGRYASASEVVRDALRELEEREEKLKILRHQIDKGWQQADRGEFAEDWSLQSLNEKLDR
EQ

Nucleotide

• Length: 249 bp

>AT23531 NC_011989:2185840-2186088 [Agrobacterium vitis S4]
ATGGCAACAACCAGCCTGACACTTGGCCCGCATTGGGAAGGCTTCATCAAGCAGCAGATAAGCAGTGGCCGCTACGCCTC
TGCGAGCGAAGTGGTGCGAGACGCGCTCCGCGAGTTGGAGGAGCGGGAAGAAAAGCTGAAAATTTTGCGCCATCAGATCG
ACAAGGGCTGGCAACAAGCAGATCGTGGAGAATTTGCTGAGGATTGGTCGCTCCAGTCACTCAATGAAAAACTCGACCGC
GAACAATGA

Structures

Antitoxin

• AlphaFold DB: B9JXB9