Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 233423..233991 Replicon chromosome
Accession NZ_CP091975
Organism Vibrio sp. DW001

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag L3V77_RS01110 Protein ID WP_275135385.1
Coordinates 233707..233991 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L3V77_RS01105 Protein ID WP_275135384.1
Coordinates 233423..233704 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L3V77_RS01095 (L3V77_01095) 230328..231494 + 1167 WP_275135382.1 nucleotide sugar dehydrogenase -
L3V77_RS01100 (L3V77_01100) 231660..232991 + 1332 WP_275135383.1 MBL fold metallo-hydrolase -
L3V77_RS01105 (L3V77_01105) 233423..233704 + 282 WP_275135384.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
L3V77_RS01110 (L3V77_01110) 233707..233991 + 285 WP_275135385.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L3V77_RS01115 (L3V77_01115) 234185..234820 + 636 WP_275135386.1 TetR/AcrR family transcriptional regulator -
L3V77_RS01120 (L3V77_01120) 234829..235788 + 960 WP_275135387.1 DHH family phosphoesterase -
L3V77_RS01125 (L3V77_01125) 235850..236854 + 1005 WP_275135388.1 NAD-dependent epimerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-44)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11379.11 Da        Isoelectric Point: 5.5966

>T235299 WP_275135385.1 NZ_CP091975:233707-233991 [Vibrio sp. DW001]
MKLKWEHQSLDDRYDIFEYLYEFNALAAEKTDSTIVNRAMLLLEHPFMGIEREDRRGRYLIIPEISMLLSYEFDGDLIRI
HRVIHTKQMFPEKS

Download         Length: 285 bp

>T235299 NZ_LR134236:2675101-2675208 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10963.16 Da        Isoelectric Point: 5.7711

>AT235299 WP_275135384.1 NZ_CP091975:233423-233704 [Vibrio sp. DW001]
METRVQFRIDEQTKSLAQKAIERKGGTLSDACRKLAEDLAQEQRQFENHDSWLTDQINTAFDKYDQGEAKFFSHDEAERI
MEDRKNKIRNKAL

Download         Length: 282 bp

>AT235299 NZ_LR134236:c2675054-2674988 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References