Detailed information of TA system TA023529

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 1645317..1645931
• Replicon: chromosome
• Accession: NC_011989
• Organism: Agrobacterium vitis S4

Toxin (Protein)

• Gene name: relE
• Uniprot ID: B9JVZ6
• Locus tag: AVI_RS07820
• Protein ID: WP_015915847.1
• Coordinates: 1645680..1645931 (-)
• Length: 84 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: AVI_RS07815
• Protein ID: WP_041696517.1
• Coordinates: 1645317..1645670 (-)
• Length: 118 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AVI_RS07795	1642952..1644448	+	1497	WP_015915844.1	hypothetical protein	-
AVI_RS29005	1644464..1645069	+	606	WP_015915845.1	hypothetical protein	-
AVI_RS07810	1645073..1645312	+	240	WP_041696515.1	hypothetical protein	-
AVI_RS07815	1645317..1645670	-	354	WP_041696517.1	helix-turn-helix transcriptional regulator	Antitoxin
AVI_RS07820	1645680..1645931	-	252	WP_015915847.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
AVI_RS07825	1646017..1646625	+	609	WP_139192395.1	hypothetical protein	-
AVI_RS07830	1646622..1646864	+	243	WP_041696518.1	hypothetical protein	-
AVI_RS07835	1646861..1647298	+	438	WP_015915849.1	hypothetical protein	-
AVI_RS31045	1647327..1647485	+	159	WP_156753142.1	hypothetical protein	-
AVI_RS29010	1647482..1647868	+	387	WP_015915850.1	hypothetical protein	-
AVI_RS07845	1647964..1649505	-	1542	WP_015915851.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1647482..1657146	9664
	-	inside	Prophage	-	-	1611015..1645931	34916

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Cro/C1-type helix-turn-helix domain (62-116)

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 9378.93 Da
• Isoelectric Point: 10.5646

>T23529 WP_015915847.1 NC_011989:c1645931-1645680 [Agrobacterium vitis S4]
MKKIAYSKSSLKVLRRLPTNEAKRIAQKIEQYASDPQSMANNVKALTGSPYIRLRVGDWRVIMDDQGSVLEILKIGPRGS
VYE

Nucleotide

• Length: 252 bp

>T23529 NC_011989:c1645931-1645680 [Agrobacterium vitis S4]
ATGAAAAAGATCGCATACAGCAAATCATCATTGAAGGTTCTTCGCCGCCTGCCAACCAATGAGGCAAAGCGGATTGCCCA
GAAGATCGAGCAATATGCGAGCGATCCGCAGTCCATGGCGAACAACGTAAAGGCACTGACCGGCTCGCCTTACATCCGGT
TGCGGGTCGGTGATTGGCGGGTGATCATGGACGATCAAGGCAGCGTCCTTGAAATCCTCAAGATCGGCCCGCGTGGTAGC
GTCTACGAATAG

Antitoxin

Protein

• Length: 118 a.a.
• Molecular weight: 12663.47 Da
• Isoelectric Point: 4.3233

>AT23529 WP_041696517.1 NC_011989:c1645670-1645317 [Agrobacterium vitis S4]
MQTIITPNGETLVVLPLAEYESLIDHSDIAAADKVKADIAAGDDELVPAEVVNQLLAGEHPVKVWRMFRKMTARELAEQA
GISAPYVSEIESGKKDGSFATMKKIAEALRVDLDDLA

Nucleotide

• Length: 354 bp

>AT23529 NC_011989:c1645670-1645317 [Agrobacterium vitis S4]
ATGCAGACCATCATTACCCCGAACGGCGAAACGCTGGTCGTGCTGCCCCTGGCAGAATACGAAAGCCTGATCGACCACAG
CGACATTGCAGCAGCCGATAAGGTCAAGGCGGATATCGCCGCAGGTGACGACGAGCTTGTTCCCGCCGAAGTCGTCAACC
AGCTTCTTGCCGGTGAACACCCGGTCAAGGTCTGGCGCATGTTTCGCAAGATGACGGCGCGGGAATTGGCCGAACAGGCC
GGTATCAGCGCGCCCTATGTTTCCGAGATCGAGAGCGGCAAGAAGGACGGAAGCTTTGCGACGATGAAGAAGATCGCAGA
GGCTCTTCGTGTCGATCTGGACGATCTGGCGTAG

Structures

Toxin

• AlphaFold DB: B9JVZ6